Douglas Easton
Douglas Easton
Professor of Genetic Epidemiology, University of Cambridge
Geverifieerd e-mailadres voor medschl.cam.ac.uk
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Wellcome Trust Case Control Consortium
Nature 447 (7145), 661, 2007
79762007
Identification of the breast cancer susceptibility gene BRCA2
R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, ...
Nature 378 (6559), 789-792, 1995
43121995
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies
A Antoniou, PDP Pharoah, S Narod, HA Risch, JE Eyfjord, JL Hopper, ...
The American Journal of Human Genetics 72 (5), 1117-1130, 2003
40432003
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
D Ford, DF Easton, M Stratton, S Narod, D Goldgar, P Devilee, DT Bishop, ...
The American Journal of Human Genetics 62 (3), 676-689, 1998
36531998
Patterns of somatic mutation in human cancer genomes
C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ...
Nature 446 (7132), 153-158, 2007
32502007
Genome-wide association study identifies novel breast cancer susceptibility loci
DF Easton, KA Pooley, AM Dunning, PDP Pharoah, D Thompson, ...
Nature 447 (7148), 1087-1093, 2007
25982007
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
R Wooster, SL Neuhausen, J Mangion, Y Quirk, D Ford, N Collins, ...
Science 265 (5181), 2088-2090, 1994
24971994
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
24472004
Risks of cancer in BRCA1-mutation carriers
D Ford, DF Easton, DT Bishop, SA Narod, DE Goldgar
The Lancet 343 (8899), 692-695, 1994
22511994
Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
DF Easton, D Ford, DT Bishop
American journal of human genetics 56 (1), 265, 1995
20251995
Polychemotherapy for early breast cancer: an overview of the randomised trials
Early Breast Cancer Trialists' Collaborative Group
The Lancet 352 (9132), 930-942, 1998
18751998
International network of cancer genome projects
International Cancer Genome Consortium
Nature 464 (7291), 993, 2010
17902010
Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.
DF Easton, DT Bishop, D Ford, GP Crockford
American journal of human genetics 52 (4), 678, 1993
17341993
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
16232012
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
PR Burton, DG Clayton, LR Cardon, N Craddock, P Deloukas, ...
Nature genetics 39 (11), 1329-1337, 2007
12592007
Cancer incidence in BRCA1 mutation carriers
D Thompson, DF Easton
Journal of the National Cancer Institute 94 (18), 1358-1365, 2002
12372002
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations
CHEK2-Breast Cancer Consortium
Nature genetics 31 (1), 55, 2002
12352002
Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers
KB Kuchenbaecker, JL Hopper, DR Barnes, KA Phillips, TM Mooij, ...
Jama 317 (23), 2402-2416, 2017
12062017
Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands
DE Goldgar, DF Easton, LA Cannon-Albright, MH Skolnick
JNCI: Journal of the National Cancer Institute 86 (21), 1600-1608, 1994
11781994
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
T Powles, R Eeles, S Ashley, D Easton, J Chang, M Dowsett, A Tidy, ...
The lancet 352 (9122), 98-101, 1998
11351998
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