Adrian V. Lee
Adrian V. Lee
Professor of Pharmacology, University of Pittsburgh
Geverifieerd e-mailadres voor pitt.edu - Homepage
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An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ...
Cell 173 (2), 400-416. e11, 2018
9692018
Estrogen receptor–positive, progesterone receptor–negative breast cancer: association with growth factor receptor expression and tamoxifen resistance
G Arpino, H Weiss, AV Lee, R Schiff, S De Placido, CK Osborne, ...
Journal of the National Cancer Institute 97 (17), 1254-1261, 2005
5452005
Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy
X Cui, R Schiff, G Arpino, CK Osborne, AV Lee
Journal of clinical oncology 23 (30), 7721-7735, 2005
5292005
Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expression in Vitro and in Vivo
AV Lee, JG Jackson, JL Gooch, SG Hilsenbeck, E Coronado-Heinsohn, ...
Molecular endocrinology 13 (5), 787-796, 1999
4151999
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases
S Liu, M Umezu-Goto, M Murph, Y Lu, W Liu, F Zhang, S Yu, LC Stephens, ...
Cancer cell 15 (6), 539-550, 2009
3832009
Crosstalk between the insulin-like growth factors and estrogens in breast cancer
D Yee, AV Lee
Journal of mammary gland biology and neoplasia 5 (1), 107-115, 2000
2792000
Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis
CJ Creighton, A Casa, ZW Lazard, S Huang, A Tsimelzon, SG Hilsenbeck, ...
Journal of clinical oncology 26 (25), 4078, 2008
2682008
Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway …
X Cui, P Zhang, W Deng, S Oesterreich, Y Lu, GB Mills, AV Lee
Molecular endocrinology 17 (4), 575-588, 2003
2642003
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer
CJ Creighton, X Fu, BT Hennessy, AJ Casa, Y Zhang, ...
Breast cancer research 12 (3), 1-12, 2010
2632010
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an …
HJ Kim, BC Litzenburger, X Cui, DA Delgado, BC Grabiner, X Lin, ...
Molecular and cellular biology 27 (8), 3165-3175, 2007
2482007
Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells
AV Lee, CN Weng, JG Jackson, D Yee
Journal of Endocrinology 152 (1), 39-47, 1997
2441997
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor
JM Carboni, AV Lee, DL Hadsell, BR Rowley, FY Lee, DK Bol, ...
Cancer research 65 (9), 3781-3787, 2005
2302005
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice
SQ Kuang, L Liao, H Zhang, AV Lee, BW O’Malley, J Xu
Cancer research 64 (5), 1875-1885, 2004
2242004
Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival.
RL Rocha, SG Hilsenbeck, JG Jackson, CL VanDenBerg, C n Weng, ...
Clinical Cancer Research 3 (1), 103-109, 1997
2181997
MCF-7 cells—changing the course of breast cancer research and care for 45 years
AV Lee, S Oesterreich, NE Davidson
JNCI: Journal of the National Cancer Institute 107 (7), 2015
2172015
Re-expression of estrogen receptor α in estrogen receptor α-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth
S Oesterreich, P Zhang, RL Guler, X Sun, EM Curran, WV Welshons, ...
Cancer research 61 (15), 5771-5777, 2001
1942001
Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2
RK Dearth, X Cui, HJ Kim, DL Hadsell, AV Lee
Cell cycle 6 (6), 705-713, 2007
1922007
A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells
D Sachdev, JS Hartell, AV Lee, X Zhang, D Yee
Journal of Biological Chemistry 279 (6), 5017-5024, 2004
1922004
Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2
RK Dearth, X Cui, HJ Kim, I Kuiatse, NA Lawrence, X Zhang, J Divisova, ...
Molecular and cellular biology 26 (24), 9302-9314, 2006
1892006
Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions
DL Kleinberg, TL Wood, PA Furth, AV Lee
Endocrine reviews 30 (1), 51-74, 2009
1722009
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Artikelen 1–20