CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ... Nature medicine 24 (1), 20, 2018 | 1243 | 2018 |
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas RG Majzner, S Ramakrishna, KW Yeom, S Patel, H Chinnasamy, ... Nature 603 (7903), 934-941, 2022 | 424 | 2022 |
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer IM Kim, T Ackerson, S Ramakrishna, M Tretiakova, IC Wang, TV Kalin, ... Cancer research 66 (4), 2153-2161, 2006 | 419 | 2006 |
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial JY Spiegel, S Patel, L Muffly, NM Hossain, J Oak, JH Baird, MJ Frank, ... Nature medicine 27 (8), 1419-1431, 2021 | 348 | 2021 |
Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas AH Long, SL Highfill, Y Cui, JP Smith, AJ Walker, S Ramakrishna, ... Cancer immunology research 4 (10), 869-880, 2016 | 294 | 2016 |
Preclinical development of bivalent chimeric antigen receptors targeting both CD19 and CD22 H Qin, S Ramakrishna, S Nguyen, TJ Fountaine, A Ponduri, ... Molecular Therapy-Oncolytics 11, 127-137, 2018 | 235 | 2018 |
The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature IM Kim, S Ramakrishna, GA Gusarova, HM Yoder, RH Costa, ... Journal of Biological Chemistry 280 (23), 22278-22286, 2005 | 181 | 2005 |
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence S Ramakrishna, SL Highfill, Z Walsh, SM Nguyen, H Lei, JF Shern, H Qin, ... Clinical Cancer Research, 2019 | 140 | 2019 |
Delayed cancer diagnoses and high mortality in children during the COVID‐19 pandemic YY Ding, S Ramakrishna, AH Long, CA Phillips, R Montiel‐Esparza, ... Pediatric Blood & Cancer, 2020 | 83 | 2020 |
Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box m1 transcription factor S Ramakrishna, IM Kim, V Petrovic, D Malin, IC Wang, TV Kalin, L Meliton, ... Developmental dynamics: an official publication of the American Association …, 2007 | 78 | 2007 |
Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression D Malin, IM Kim, E Boetticher, TV Kalin, S Ramakrishna, L Meliton, ... Molecular and cellular biology 27 (7), 2486-2498, 2007 | 77 | 2007 |
CD22-Directed CAR T-Cell Therapy Induces Complete Remissions in CD19-Directed CAR-Refractory Large B-Cell Lymphoma JH Baird, MJ Frank, J Craig, S Patel, JY Spiegel, B Sahaf, JS Oak, ... Blood, 2020 | 64 | 2020 |
Functional characterization of evolutionarily conserved DNA regions in forkhead box f1 gene locus IM Kim, Y Zhou, S Ramakrishna, DE Hughes, J Solway, RH Costa, ... Journal of Biological Chemistry 280 (45), 37908-37916, 2005 | 64 | 2005 |
Phase I Trial Using CD19/CD22 Bispecific CAR T Cells in Pediatric and Adult Acute Lymphoblastic Leukemia (ALL) LM Schultz, LS Muffly, JY Spiegel, S Ramakrishna, N Hossain, C Baggott, ... Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | 51 | 2019 |
Prospects and Challenges for Use of CAR T Cell Therapies in Solid Tumors S Ramakrishna, V Barsan, C Mackall Expert Opinion on Biological Therapy, 2020 | 42 | 2020 |
CD22-CAR T cells induce remissions in CD19-CAR naïve and resistant B-ALL TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ... Nature medicine 24 (1), 20, 2018 | 37 | 2018 |
Novel CD19/CD22 bicistronic chimeric antigen receptors outperform single or bivalent cars in eradicating CD19+ CD22+, CD19-, and CD22-pre-B leukemia H Qin, SM Nguyen, S Ramakrishna, S Tarun, L Yang, NP Verdini, W Haso, ... Blood 130 (Supplement 1), 810-810, 2017 | 32 | 2017 |
Combined effects of prenatal inhibition of vasculogenesis and neurogenesis on rat brain development QY Fan, S Ramakrishna, N Marchi, V Fazio, K Hallene, D Janigro Neurobiology of disease 32 (3), 499-509, 2008 | 22 | 2008 |
Immunotherapy for the Treatment of Acute Lymphoblastic Leukemia V Barsan, S Ramakrishna, KL Davis Current Oncology Reports 22 (2), 11, 2020 | 18 | 2020 |
Intensification of lymphodepletion optimizes CAR re-treatment efficacy H Shalabi, NN Shah, TJ Fry, B Yates, C Delbrook, C Yuan, ... Blood 130 (Supplement 1), 3889-3889, 2017 | 11 | 2017 |