Imran Shah
Imran Shah
Computational Systems Biologist, US EPA
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The BioPAX community standard for pathway data sharing
E Demir, MP Cary, S Paley, K Fukuda, C Lemer, I Vastrik, G Wu, ...
Nature biotechnology 28 (9), 935-942, 2010
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
RS Judson, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
Environmental health perspectives 118 (4), 485-492, 2010
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
AJ Williams, CM Grulke, J Edwards, AD McEachran, K Mansouri, ...
Journal of cheminformatics 9 (1), 61, 2017
Computational toxicology—a state of the science mini review
RJ Kavlock, G Ankley, J Blancato, M Breen, R Conolly, D Dix, K Houck, ...
Toxicological sciences 103 (1), 14-27, 2008
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
In Vitro and Modelling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Programme
R Judson, K Houck, M Martin, T Knudsen, RS Thomas, N Sipes, I Shah, ...
Basic & clinical pharmacology & toxicology 115 (1), 69-76, 2014
PathMiner: predicting metabolic pathways by heuristic search
DC McShan, S Rao, I Shah
Bioinformatics 19 (13), 1692-1698, 2003
Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury
M Vinken, B Landesmann, M Goumenou, S Vinken, I Shah, H Jaeschke, ...
toxicological sciences 136 (1), 97-106, 2013
Predicting Hepatotoxicity Using ToxCast in Vitro Bioactivity and Chemical Structure
J Liu, K Mansouri, RS Judson, MT Martin, H Hong, M Chen, X Xu, ...
Chemical research in toxicology 28 (4), 738-751, 2015
Toxicokinetic triage for environmental chemicals
JF Wambaugh, BA Wetmore, R Pearce, C Strope, R Goldsmith, JP Sluka, ...
Toxicological Sciences 147 (1), 55-67, 2015
Predicting enzyme function from sequence: a systematic appraisal
I Shah, L Hunter
Proceedings/... International Conference on Intelligent Systems for …, 1997
A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model
R Judson, F Elloumi, RW Setzer, Z Li, I Shah
BMC bioinformatics 9 (1), 241, 2008
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis
NC Kleinstreuer, DJ Dix, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
toxicological sciences 131 (1), 40-55, 2013
Simulating microdosimetry in a virtual hepatic lobule
J Wambaugh, I Shah
PLoS Comput Biol 6 (4), e1000756, 2010
Using nuclear receptor activity to stratify hepatocarcinogens
I Shah, K Houck, RS Judson, RJ Kavlock, MT Martin, DM Reif, ...
PLoS One 6 (2), e14584, 2011
Benchmark studies on face recognition
S Gutta, J Huang, D Singh, I Shah, B Takács, H Wechsler
Proceedings of the International Workshop on Automatic Face-and Gesture …, 1995
Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information
I Shah, J Liu, RS Judson, RS Thomas, G Patlewicz
Regulatory Toxicology and Pharmacology 79, 12-24, 2016
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ...
Toxicological Sciences 169 (2), 317-332, 2019
Using ToxCast™ data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure
I Shah, RW Setzer, J Jack, KA Houck, RS Judson, TB Knudsen, J Liu, ...
Environmental health perspectives 124 (7), 910-919, 2016
Current approaches and future role of high content imaging in safety sciences and drug discovery
E Van Vliet, M Daneshian, M Beilmann, A Davies, E Fava, R Fleck, Y Julé, ...
Alternatives to Animal Experimentation: ALTEX 31 (4), 479-493, 2014
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