Rapid covalent-probe discovery by electrophile-fragment screening E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ... Journal of the American Chemical Society 141 (22), 8951-8968, 2019 | 244 | 2019 |
Cell cycle regulatory functions of the KSHV oncoprotein LANA F Wei, J Gan, C Wang, C Zhu, Q Cai Frontiers in microbiology 7, 334, 2016 | 49 | 2016 |
Highlighting the proteasome: using fluorescence to visualize proteasome activity and distribution J Gan, Y Leestemaker, A Sapmaz, H Ovaa Frontiers in Molecular Biosciences 6, 14, 2019 | 39 | 2019 |
Silver nanoparticles selectively induce human oncogenic γ-herpesvirus-related cancer cell death through reactivating viral lytic replication C Wan, J Tai, J Zhang, Y Guo, Q Zhu, D Ling, F Gu, J Gan, C Zhu, Y Wang, ... Cell Death & Disease 10 (6), 392, 2019 | 34 | 2019 |
Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases N Wössner, Z Alhalabi, J González, S Swyter, J Gan, K Schmidtkunz, ... Frontiers in Oncology 10, 657, 2020 | 25 | 2020 |
STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency Y Wang, S Du, C Zhu, C Wang, N Yu, Z Lin, J Gan, Y Guo, X Huang, Y He, ... PLoS pathogens 16 (3), e1008447, 2020 | 19 | 2020 |
Prevalence and correlates of Mycoplasma genitalium infection among prostatitis patients in Shanghai, China X Mo, C Zhu, J Gan, C Wang, F Wei, W Gong, Q Cai Sexual health 13 (5), 474-479, 2016 | 17 | 2016 |
Proteomic profiling identifies the SIM‐associated complex of KSHV‐encoded LANA J Gan, C Wang, Y Jin, Y Guo, F Xu, Q Zhu, L Ding, H Shang, J Wang, ... Proteomics 15 (12), 2023-2037, 2015 | 16 | 2015 |
Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties BT Xin, J Gan, DJ Fernandez, KP Knobeloch, PP Geurink, H Ovaa Organic & Biomolecular Chemistry 17 (48), 10148-10152, 2019 | 13 | 2019 |
Manipulation of ubiquitin/SUMO pathways in human herpesviruses infection J Gan, N Qiao, R Strahan, C Zhu, L Liu, SC Verma, F Wei, Q Cai Reviews in Medical Virology 26 (6), 435-445, 2016 | 13 | 2016 |
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism J Gan, A Pinto-Fernández, D Flierman, JJLL Akkermans, DP O’Brien, ... Proceedings of the National Academy of Sciences 120 (50), e2315163120, 2023 | 4 | 2023 |
IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity S Thomaidou, A Munoz Garcia, S de Lange, J Gan, AR van der Slik, ... Diabetologia 66 (11), 2075-2086, 2023 | 4 | 2023 |
Proteomic Profiling Identifies Kaposi’s Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANASIM-Associated Proteins in Hypoxia X Liu, J Gan, S Du, C Zhu, Y Wang, Y Jia, D Zhang, D Qu, F Wei, ... Msystems 6 (6), e01109-21, 2021 | 2 | 2021 |
Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2 J Gan, J de Vries, JJLL Akkermans, Y Mohammed, RTN Tjokrodirijo, ... ACS Chemical Biology 18 (9), 2003-2013, 2023 | 1 | 2023 |
USP16 is an ISG15 cross-reactive deubiquitinase targeting a subset of metabolic pathway-related proteins J Gan, A Pinto-Fernández, D Flierman, JJLL Akkermans, DP O'Brien, ... bioRxiv, 2023.06. 26.546496, 2023 | 1 | 2023 |
Exploring Ubiquitin and ISG15 Biology with Chemical Tools J Gan Leiden University, 2022 | | 2022 |
Chemical improvement and cellular validation of OTUB2 inhibitors provides evidence for novel OTUB2 (auto-) regulatory mechanisms J Gan, J de Vries, H van Dam, JJLL Akkermans, RTN Tjokrodirijo, ... Exploring Ubiquitin and ISG15 Biology with Chemical Tools, 131, 2022 | | 2022 |
The affair of USP16: an ISG15 cross-reactive deubiquitinase J Gan, A Pinto-Fernández, D Flierman, H van Dam, DP O’Brien, ... Exploring Ubiquitin and ISG15 Biology with Chemical Tools, 95, 2022 | | 2022 |
Development of small molecule inhibitors targeting murine USP18 J Gan, V Pol, H van Dam, R Kooij, DJ Fernandez, KP Knobeloch, ... Exploring Ubiquitin and ISG15 Biology with Chemical Tools, 77, 2022 | | 2022 |
Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain GJ van der Heden van Noort, J Gan, H Ovaa Proceedings of the National Academy of Sciences 116 (16), 7614-7616, 2019 | | 2019 |