| The validation of surrogate endpoints in meta-analyses of randomized experiments M Buyse, G Molenberghs, T Burzykowski, D Renard, H Geys Biostatistics 1 (1), 49-67, 2000 | 647 | 2000 |
| Validation of surrogate end points in multiple randomized clinical trials with failure time end points T Burzykowski, G Molenberghs, M Buyse, H Geys, D Renard Journal of the Royal Statistical Society Series C: Applied Statistics 50 (4 …, 2001 | 269 | 2001 |
| Building multivariable regression models with continuous covariates in clinical epidemiology P Royston, W Sauerbrei Methods of information in medicine 44 (04), 561-571, 2005 | 238 | 2005 |
| Topics in modelling of clustered data M Aerts, G Molenberghs, LM Ryan, H Geys Chapman and Hall/CRC, 2002 | 192 | 2002 |
| Pseudolikelihood modeling of multivariate outcomes in developmental toxicology H Geys, G Molenberghs, LM Ryan Journal of the American Statistical Association 94 (447), 734-745, 1999 | 160 | 1999 |
| Statistical challenges in the evaluation of surrogate endpoints in randomized trials G Molenberghs, M Buyse, H Geys, D Renard, T Burzykowski, A Alonso Controlled Clinical Trials 23 (6), 607-625, 2002 | 140 | 2002 |
| A pairwise likelihood approach to estimation in multilevel probit models D Renard, G Molenberghs, H Geys Computational Statistics & Data Analysis 44 (4), 649-667, 2004 | 136 | 2004 |
| Evaluation of surrogate endpoints in randomized experiments with mixed discrete and continuous outcomes G Molenberghs, H Geys, M Buyse Statistics in medicine 20 (20), 3023-3038, 2001 | 117 | 2001 |
| Applying concepts of generalizability theory on clinical trial data to investigate sources of variation and their impact on reliability T Vangeneugden, A Laenen, H Geys, D Renard, G Molenberghs Biometrics 61 (1), 295-304, 2005 | 109 | 2005 |
| Applying linear mixed models to estimate reliability in clinical trial data with repeated measurements T Vangeneugden, A Laenen, H Geys, D Renard, G Molenberghs Controlled Clinical Trials 25 (1), 13-30, 2004 | 88 | 2004 |
| A unifying approach for surrogate marker validation based on Prentice's criteria A Alonso, G Molenberghs, H Geys, M Buyse, T Vangeneugden Statistics in medicine 25 (2), 205-221, 2006 | 83 | 2006 |
| Recommendations on the statistical analysis of the Comet assay J Bright, M Aylott, S Bate, H Geys, P Jarvis, J Saul, R Vonk Pharmaceutical statistics 10 (6), 485-493, 2011 | 78 | 2011 |
| Prentice's approach and the meta-analytic paradigm: a reflection on the role of statistics in the evaluation of surrogate endpoints A Alonso, G Molenberghs, T Burzykowski, D Renard, H Geys, Z Shkedy, ... Biometrics 60 (3), 724-728, 2004 | 78 | 2004 |
| Model averaging using fractional polynomials to estimate a safe level of exposure C Faes, M Aerts, H Geys, G Molenberghs Risk Analysis: An International Journal 27 (1), 111-123, 2007 | 76 | 2007 |
| Validation of surrogate endpoints in multiple randomized clinical trials with discrete outcomes D Renard, H Geys, G Molenberghs, T Burzykowski, M Buyse Biometrical Journal: Journal of Mathematical Methods in Biosciences 44 (8 …, 2002 | 76 | 2002 |
| Modulation of group II metabotropic glutamate receptor (mGlu2) elicits common changes in rat and mice sleep–wake architecture A Ahnaou, FM Dautzenberg, H Geys, H Imogai, A Gibelin, D Moechars, ... European journal of pharmacology 603 (1-3), 62-72, 2009 | 72 | 2009 |
| The concordance between nonclinical and phase I clinical cardiovascular assessment from a cross-company data sharing initiative L Ewart, M Aylott, M Deurinck, M Engwall, DJ Gallacher, H Geys, P Jarvis, ... Toxicological Sciences 142 (2), 427-435, 2014 | 71 | 2014 |
| Pseudo-likelihood inference for clustered binary data H Geys1, G Molenberghs1, LM Ryan2 Communications in statistics-theory and methods 26 (11), 2743-2767, 1997 | 65 | 1997 |
| A high‐dimensional joint model for longitudinal outcomes of different nature C Faes, M Aerts, G Molenberghs, H Geys, G Teuns, L Bijnens Statistics in medicine 27 (22), 4408-4427, 2008 | 56 | 2008 |
| Trend of cervical cancer mortality in Belgium (1954–1994): tentative solution for the certification problem of unspecified uterine cancer M Arbyn, H Geys International journal of cancer 102 (6), 649-654, 2002 | 53 | 2002 |
