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Bram De Laere
Bram De Laere
Ghent University and Karolinska Institute
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Efficacy of cabazitaxel in castration-resistant prostate cancer is independent of the presence of AR-V7 in circulating tumor cells
W Onstenk, AM Sieuwerts, J Kraan, M Van, AJM Nieuweboer, ...
European urology 68 (6), 939-945, 2015
2762015
Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
DJE Peeters, B De Laere, GG Van den Eynden, SJ Van Laere, F Rothé, ...
British journal of cancer 108 (6), 1358-1367, 2013
1852013
TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer
B De Laere, S Oeyen, M Mayrhofer, T Whitington, PJ van Dam, ...
Clinical cancer research 25 (6), 1766-1773, 2019
1592019
Comprehensive profiling of the androgen receptor in liquid biopsies from castration-resistant prostate cancer reveals novel intra-AR structural variation and splice variant …
B De Laere, PJ van Dam, T Whitington, M Mayrhofer, EH Diaz, ...
European urology 72 (2), 192-200, 2017
1472017
Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
M Mayrhofer, B De Laere, T Whitington, P Van Oyen, C Ghysel, J Ampe, ...
Genome medicine 10, 1-13, 2018
1292018
Differential impact of RB status on E2F1 reprogramming in human cancer
C McNair, K Xu, AC Mandigo, M Benelli, B Leiby, D Rodrigues, J Lindberg, ...
The Journal of clinical investigation 128 (1), 341-358, 2018
1062018
Evaluation and consequences of heterogeneity in the circulating tumor cell compartment
A Brouwer, B De Laere, D Peeters, M Peeters, R Salgado, L Dirix, ...
Oncotarget 7 (30), 48625, 2016
682016
Consensus statement on circulating biomarkers for advanced prostate cancer.
S Sumanasuriya, AG Omlin, AJ Armstrong, G Attard, KN Chi, CL Bevan, ...
Journal of Clinical Oncology 36 (6_suppl), 299-299, 2018
432018
Prognostic value of low-pass whole genome sequencing of circulating tumor DNA in metastatic castration-resistant prostate cancer
M Nørgaard, MT Bjerre, J Fredsøe, S Vang, JB Jensen, B De Laere, ...
Clinical Chemistry 69 (4), 386-398, 2023
392023
Tissue-and blood-derived genomic biomarkers for metastatic hormone-sensitive prostate cancer: a systematic review
K Van der Eecken, J Vanwelkenhuyzen, MP Deek, PT Tran, E Warner, ...
European Urology Oncology 4 (6), 914-923, 2021
352021
The ProBio trial: molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer
A Crippa, B De Laere, A Discacciati, B Larsson, JT Connor, EE Gabriel, ...
Trials 21, 1-10, 2020
352020
Circulating tumor cells and survival in abiraterone‐and enzalutamide‐treated patients with castration‐resistant prostate cancer
B De Laere, S Oeyen, P Van Oyen, C Ghysel, J Ampe, P Ost, W Demey, ...
The Prostate 78 (6), 435-445, 2018
292018
AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel
AM Sieuwerts, W Onstenk, J Kraan, CM Beaufort, M Van, B De Laere, ...
Molecular Oncology 13 (8), 1795-1807, 2019
262019
Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer
NM Fonseca, C Maurice-Dror, C Herberts, W Tu, W Fan, AJ Murtha, ...
Nature Communications 15 (1), 1828, 2024
212024
Androgen receptor burden and poor response to abiraterone or enzalutamide in TP53 wild-type metastatic castration-resistant prostate cancer
B De Laere, P Rajan, H Grönberg, L Dirix, J Lindberg
JAMA oncology 5 (7), 1060-1062, 2019
202019
An in-depth evaluation of the validity and logistics surrounding the testing of AR-V7 mRNA expression in circulating tumor cells
AM Sieuwerts, B Mostert, M van der Vlugt-Daane, J Kraan, CM Beaufort, ...
The Journal of Molecular Diagnostics 20 (3), 316-325, 2018
182018
Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization
G Renaud, M Nørgaard, J Lindberg, H Grönberg, B De Laere, JB Jensen, ...
Elife 11, e71569, 2022
162022
Toward methodology for detection of cancer-promoting S100A4 protein conformations in subnanomolar concentrations using Raman and SERS
S Abdali, B De Laere, M Poulsen, M Grigorian, E Lukanidin, J Klingelhofer
The Journal of Physical Chemistry C 114 (16), 7274-7279, 2010
152010
Using 68Ga-PSMA-11 PET/CT for therapy response assessment in patients with metastatic castration-resistant prostate cancer: application of EAU/EANM recommendations in clinical …
CS Denis, F Cousin, B De Laere, R Hustinx, BR Sautois, N Withofs
Journal of Nuclear Medicine 63 (12), 1815-1821, 2022
132022
Clinical trial protocol for ProBio: an outcome-adaptive and randomised multiarm biomarker-driven study in patients with metastatic prostate cancer
B De Laere, A Crippa, A Discacciati, B Larsson, J Oldenburg, A Mortezavi, ...
European Urology Focus 8 (6), 1617-1621, 2022
132022
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