Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ... Cell 173 (3), 693-705. e22, 2018 | 289 | 2018 |
Atomic basis of CRM1-cargo recognition, release and inhibition HYJ Fung, YM Chook Seminars in cancer biology 27, 52-61, 2014 | 154 | 2014 |
Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies ZA Hing, HYJ Fung, P Ranganathan, S Mitchell, D El-Gamal, JA Woyach, ... Leukemia 30 (12), 2364-2372, 2016 | 135 | 2016 |
Karyopherin-mediated nucleocytoplasmic transport CE Wing, HYJ Fung, YM Chook Nature reviews Molecular cell biology 23 (5), 307-328, 2022 | 127 | 2022 |
Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization ES Pinarbasi, T Cağatay, HYJ Fung, YC Li, YM Chook, PJ Thomas Scientific reports 8 (1), 7083, 2018 | 120 | 2018 |
IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies HYJ Fung, M Birol, E Rhoades Current opinion in structural biology 49, 36-43, 2018 | 111 | 2018 |
Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination JD Haines, O Herbin, B De La Hera, OG Vidaurre, GA Moy, Q Sun, ... Nature neuroscience 18 (4), 511-520, 2015 | 90 | 2015 |
Structural determinants of nuclear export signal orientation in binding to exportin CRM1 HYJ Fung, SC Fu, CA Brautigam, YM Chook elife 4, e10034, 2015 | 86 | 2015 |
Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals HYJ Fung, SC Fu, YM Chook elife 6, e23961, 2017 | 85 | 2017 |
Correlation of CRM1-NES affinity with nuclear export activity SC Fu, HYJ Fung, T Cağatay, J Baumhardt, YM Chook Molecular biology of the cell 29 (17), 2037-2044, 2018 | 46 | 2018 |
An update to the CRM1 cargo/NES database NESdb HYJ Fung, A Niesman, YM Chook Molecular biology of the cell 32 (6), 467-469, 2021 | 11 | 2021 |
Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice Y Xie, HYJ Fung, EP Newberry, S Kennedy, J Luo, RM Crooke, ... Journal of lipid research 55 (3), 540-548, 2014 | 11 | 2014 |
Structural characterization of tau in fuzzy tau: Tubulin complexes HYJ Fung, KM McKibben, J Ramirez, K Gupta, E Rhoades Structure 28 (3), 378-384. e4, 2020 | 10 | 2020 |
Structure of IMPORTIN-4 bound to the H3–H4–ASF1 histone–histone chaperone complex NE Bernardes, HYJ Fung, Y Li, Z Chen, YM Chook Proceedings of the National Academy of Sciences 119 (38), e2207177119, 2022 | 8 | 2022 |
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP• Kap114• H2A-H2B complex J Jiou, JM Shaffer, NE Bernades, HYJ Fung, J Kikumoto Dias, S D’Arcy, ... Proceedings of the National Academy of Sciences 120 (29), e2301199120, 2023 | 4 | 2023 |
Binding affinity measurement of nuclear export signal peptides to their exporter CRM1 HYJ Fung, YM Chook The Nuclear Pore Complex: Methods and Protocols, 245-256, 2022 | 3 | 2022 |
Molecular basis of RanGTP-activated release of Histones H2A-H2B from Importin-9 JM Shaffer, J Jiou, K Tripathi, OS Olaluwoye, HYJ Fung, YM Chook, ... Structure 31 (8), 903-911. e3, 2023 | 2 | 2023 |
A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders A Gonzalez, HJ Kim, BD Freibaum, HYJ Fung, CA Brautigam, JP Taylor, ... Structure 31 (8), 924-934. e4, 2023 | 1 | 2023 |
Crystallization of Nuclear Export Signals or Small-Molecule Inhibitors Bound to Nuclear Exporter CRM1 HYJ Fung, YM Chook The Nuclear Pore Complex: Methods and Protocols, 285-297, 2022 | 1 | 2022 |
Structural basis for Retriever-SNX17 assembly and endosomal sorting A Singla, DJ Boesch, HYJ Fung, C Ngoka, AS Enriquez, R Song, ... bioRxiv, 2024 | | 2024 |