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John Chappell
John Chappell
Associate Professor, Fralin Biomedical Research Institute at VTC
Geverifieerd e-mailadres voor vt.edu
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Local guidance of emerging vessel sprouts requires soluble Flt-1.
JC Chappell, SM Taylor, N Ferrara, VL Bautch
Developmental Cell 17 (3), 377-386, 2009
2652009
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
NC Kappas, G Zeng, JC Chappell, JB Kearney, S Hazarika, KG Kallianos, ...
The Journal of cell biology 181 (5), 847-858, 2008
2172008
Influence of injection site, microvascular pressureand ultrasound variables on microbubble-mediated delivery of microspheres to muscle
J Song, JC Chappell, M Qi, EJ VanGieson, S Kaul, RJ Price
Journal of the American College of Cardiology 39 (4), 726-731, 2002
1622002
Regulation of blood vessel sprouting
JC Chappell, DM Wiley, VL Bautch
Seminars in cell & developmental biology 22 (9), 1005-1011, 2011
1062011
Targeted delivery of nanoparticles bearing fibroblast growth factor‐2 by ultrasonic microbubble destruction for therapeutic arteriogenesis
JC Chappell, J Song, CW Burke, AL Klibanov, RJ Price
Small 4 (10), 1769-1777, 2008
1002008
Hypoxia, angiogenesis, and metabolism in the hereditary kidney cancers
JC Chappell, LB Payne, WK Rathmell
The Journal of clinical investigation 129 (2), 442-451, 2019
832019
Vascular development: genetic mechanisms and links to vascular disease
JC Chappell, VL Bautch
Current topics in developmental biology 90, 43-72, 2010
732010
Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation
J Darden, LB Payne, H Zhao, JC Chappell
Angiogenesis 22, 167-183, 2019
692019
Flt-1 (vascular endothelial growth factor receptor-1) is essential for the vascular endothelial growth factor–notch feedback loop during angiogenesis
JC Chappell, KP Mouillesseaux, VL Bautch
Arteriosclerosis, thrombosis, and vascular biology 33 (8), 1952-1959, 2013
622013
How blood vessel networks are made and measured
JC Chappell, DM Wiley, VL Bautch
Cells Tissues Organs 195 (1-2), 94-107, 2011
622011
The pericyte microenvironment during vascular development
LB Payne, H Zhao, CC James, J Darden, D McGuire, S Taylor, JW Smyth, ...
Microcirculation 26 (8), e12554, 2019
572019
Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation
JC Chappell, JG Cluceru, JE Nesmith, KP Mouillesseaux, VB Bradley, ...
Cardiovascular research 111 (1), 84-93, 2016
572016
Blood vessel anastomosis is spatially regulated by Flt1 during angiogenesis
JE Nesmith, JC Chappell, JG Cluceru, VL Bautch
Development 144 (5), 889-896, 2017
542017
Specific labeling of synaptic schwann cells reveals unique cellular and molecular features
R Castro, T Taetzsch, SK Vaughan, K Godbe, J Chappell, RE Settlage, ...
Elife 9, e56935, 2020
532020
Ultrasound-microbubble-induced neovascularization in mouse skeletal muscle
JC Chappell, AL Klibanov, RJ Price
Ultrasound in medicine & biology 31 (10), 1411-1422, 2005
492005
Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients
YL Hashambhoy, JC Chappell, SM Peirce, VL Bautch, F Mac Gabhann
Frontiers in physiology 2, 10062, 2011
482011
Targeted therapeutic applications of acoustically active microspheres in the microcirculation
JC Chappell, RJ Price
Microcirculation 13 (1), 57-70, 2006
462006
Ultrasonic microbubble destruction stimulates therapeutic arteriogenesis via the CD18-dependent recruitment of bone marrow–derived cells
JC Chappell, J Song, AL Klibanov, RJ Price
Arteriosclerosis, thrombosis, and vascular biology 28 (6), 1117-1122, 2008
412008
Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks
J Walpole, JC Chappell, JG Cluceru, F Mac Gabhann, VL Bautch, ...
Integrative biology 7 (9), 987-997, 2015
382015
Microvascular bioengineering: a focus on pericytes
H Zhao, JC Chappell
Journal of Biological Engineering 13 (1), 26, 2019
352019
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Artikelen 1–20