| hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine D Melgari, KE Brack, C Zhang, Y Zhang, A El Harchi, JS Mitcheson, ... Journal of the American Heart Association 4 (4), e001813, 2015 | 91 | 2015 |
| Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide D Melgari, Y Zhang, A El Harchi, CE Dempsey, JC Hancox Journal of Molecular and Cellular Cardiology 86, 42-53, 2015 | 65 | 2015 |
| Rapid characterization of hERG channel kinetics II: temperature dependence CL Lei, M Clerx, KA Beattie, D Melgari, JC Hancox, DJ Gavaghan, ... Biophysical Journal 117 (12), 2455-2470, 2019 | 42 | 2019 |
| Action potential clamp and pharmacology of the variant 1 short QT syndrome T618I hERG K+ channel A El Harchi, D Melgari, YH Zhang, H Zhang, JC Hancox PLoS One 7 (12), e52451, 2012 | 32 | 2012 |
| Distinct calcium/calmodulin-dependent serine protein kinase domains control cardiac sodium channel membrane expression and focal adhesion anchoring A Beuriot, CA Eichel, G Dilanian, F Louault, D Melgari, N Doisne, ... Heart Rhythm 17 (5), 786-794, 2020 | 16 | 2020 |
| Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration D Melgari, C Du, A El Harchi, Y Zhang, JC Hancox Physiological Reports 2 (10), e12165, 2014 | 15 | 2014 |
| hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes JC Hancox, D Melgari, CE Dempsey, KE Brack, J Mitcheson, GA Ng Therapeutic Advances in Drug Safety 6 (4), 177-179, 2015 | 13 | 2015 |
| Investigation of hERG1b influence on hERG channel pharmacology at physiological temperature AE Harchi, D Melgari, H Zhang, JC Hancox Journal of Pharmacology and Pharmacotherapeutics 9 (2), 92-103, 2018 | 12 | 2018 |
| Propranolol attenuates late sodium current in a long QT syndrome type 3-human induced pluripotent stem cell model S Hirose, T Makiyama, D Melgari, Y Yamamoto, Y Wuriyanghai, F Yokoi, ... Frontiers in Cell and Developmental Biology 8, 761, 2020 | 10 | 2020 |
| Microtubule polymerization state and clathrin-dependent internalization regulate dynamics of cardiac potassium channel: microtubule and clathrin control of KV1. 5 channel D Melgari, C Barbier, G Dilanian, C Rücker-Martin, N Doisne, ... Journal of Molecular and Cellular Cardiology 144, 127-139, 2020 | 10 | 2020 |
| T-Type Calcium Channels: A Mixed Blessing D Melgari, A Frosio, S Calamaio, GA Marzi, C Pappone, I Rivolta International Journal of Molecular Sciences 23 (17), 9894, 2022 | 7 | 2022 |
| Novel SCN5A p.Val1667Asp Missense Variant Segregation and Characterization in a Family with Severe Brugada Syndrome and Multiple Sudden Deaths MM Monasky, E Micaglio, G Ciconte, I Rivolta, V Borrelli, A Ghiroldi, ... International Journal of Molecular Sciences 22 (9), 4700, 2021 | 5 | 2021 |
| Automated patch-clamp and induced pluripotent stem cell-derived cardiomyocytes: A synergistic approach in the study of Brugada syndrome D Melgari, S Calamaio, A Frosio, R Prevostini, L Anastasia, C Pappone, ... International Journal of Molecular Sciences 24 (7), 6687, 2023 | 2 | 2023 |
| hERG potassium channel inhibition by ivabradine requires channel gating D Melgari, KE Brack, Y Zhang, A El Harchi, JS Mitcheson, CE Dempsey, ... Journal of molecular and cellular cardiology 87, 126-128, 2015 | 2 | 2015 |
| A novel de novo HCN2 loss‐of‐function variant causing developmental and epileptic encephalopathy treated with a ketogenic diet JC DiFrancesco, F Ragona, C Murano, A Frosio, D Melgari, A Binda, ... Epilepsia 64 (12), e222-e228, 2023 | 1 | 2023 |
| Increased CaV1.2 late current by a CACNA1C p.R412M variant causes an atypical Timothy syndrome without syndactyly J Ozawa, S Ohno, D Melgari, Q Wang, M Fukuyama, F Toyoda, ... Scientific Reports 12 (1), 18984, 2022 | 1 | 2022 |
| Alterations of the Sialylation Machinery in Brugada Syndrome A Ghiroldi, G Ciconte, P Creo, A Tarantino, D Melgari, S D’Imperio, ... International Journal of Molecular Sciences 23 (21), 13154, 2022 | 1 | 2022 |
| Letter by Melgari et al Regarding Article,“Ivabradine: Role in the Chronic Heart Failure Armamentarium” D Melgari, GA Ng, JC Hancox Circulation 134 (13), e296-e297, 2016 | 1 | 2016 |
| Sensitivity of flecainide inhibition of hERG channels to channel inactivation D Melgari, A El Harchi, CE Dempsey, JC Hancox Biophysical Journal 106 (2), 138a, 2014 | 1 | 2014 |
| Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights A Frosio, E Micaglio, I Polsinelli, S Calamaio, D Melgari, R Prevostini, ... International Journal of Molecular Sciences 24 (20), 15089, 2023 | | 2023 |
Jules HancoxProfessor of Cardiac Electrophysiology, University of BristolVerified email at bristol.ac.uk
