Ron Kopito
Ron Kopito
Professor of Biology, Stanford University
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Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence, RM Sampat, RR Kopito
Science 292 (5521), 1552-1555, 2001
Aggresomes: a cellular response to misfolded proteins
JA Johnston, CL Ward, RR Kopito
The Journal of cell biology 143 (7), 1883-1898, 1998
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
Trends in cell biology 10 (12), 524-530, 2000
Degradation of CFTR by the ubiquitin-proteasome pathway
CL Ward, S Omura, RR Kopito
Cell 83 (1), 121-127, 1995
Misfolded proteins partition between two distinct quality control compartments
D Kaganovich, R Kopito, J Frydman
Nature 454 (7208), 1088-1095, 2008
Subversion of cellular autophagosomal machinery by RNA viruses
WT Jackson, TH Giddings Jr, MP Taylor, S Mulinyawe, M Rabinovitch, ...
PLoS Biol 3 (5), e156, 2005
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
A Iwata, BE Riley, JA Johnston, RR Kopito
Journal of Biological Chemistry 280 (48), 40282-40292, 2005
Prion-like transmission of protein aggregates in neurodegenerative diseases
P Brundin, R Melki, R Kopito
Nature reviews Molecular cell biology 11 (4), 301-307, 2010
Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
JA Johnston, MJ Dalton, ME Gurney, RR Kopito
Proceedings of the National Academy of Sciences 97 (23), 12571-12576, 2000
ER quality control: the cytoplasmic connection
RR Kopito
Cell 88 (4), 427-430, 1997
Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation
S Sato, CL Ward, ME Krouse, JJ Wine, RR Kopito
Journal of Biological Chemistry 271 (2), 635-638, 1996
Primary structure and transmembrane orientation of the murine anion exchange protein
RR Kopito, HF Lodish
Nature 316 (6025), 234-238, 1985
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins.
CL Ward, RR Kopito
Journal of Biological Chemistry 269 (41), 25710-25718, 1994
Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation
EJ Bennett, NF Bence, R Jayakumar, RR Kopito
Molecular cell 17 (3), 351-365, 2005
Global changes to the ubiquitin system in Huntington's disease
EJ Bennett, TA Shaler, B Woodman, KY Ryu, TS Zaitseva, CH Becker, ...
Nature 448 (7154), 704-708, 2007
Biosynthesis and degradation of CFTR
RR Kopito
Physiological reviews 79 (1), S167-S173, 1999
OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1–SEL1L ubiquitin ligase complex for ERAD
JC Christianson, TA Shaler, RE Tyler, RR Kopito
Nature cell biology 10 (3), 272-282, 2008
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
PH Ren, JE Lauckner, I Kachirskaia, JE Heuser, R Melki, RR Kopito
Nature cell biology 11 (2), 219-225, 2009
Conformational disease
RR Kopito, D Ron
Nature cell biology 2 (11), E207-E209, 2000
Defining human ERAD networks through an integrative mapping strategy
JC Christianson, JA Olzmann, TA Shaler, ME Sowa, EJ Bennett, ...
Nature cell biology 14 (1), 93-105, 2012
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