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Udai Bhan Pandey
Udai Bhan Pandey
Professor, Department of Pediatrics and Neurology, University of Pittsburgh Medical Center
Geverifieerd e-mailadres voor pitt.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13163*2021
Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery
UB Pandey, CD Nichols
Pharmacological reviews 63 (2), 411-436, 2011
14332011
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
UB Pandey, Z Nie, Y Batlevi, BA McCray, GP Ritson, NB Nedelsky, ...
Nature 447 (7146), 860-864, 2007
14262007
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
JY Lee, H Koga, Y Kawaguchi, W Tang, E Wong, YS Gao, UB Pandey, ...
The EMBO journal 29 (5), 969-980, 2010
8452010
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death
X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...
Neuron 84 (6), 1213-1225, 2014
5562014
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
4182018
RNA binding antagonizes neurotoxic phase transitions of TDP-43
JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ...
Neuron 102 (2), 321-338. e8, 2019
3902019
Methods to assay Drosophila behavior
CD Nichols, J Becnel, UB Pandey
JoVE (Journal of Visualized Experiments), e3795, 2012
3362012
A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43
NA Lanson, A Maltare, H King, R Smith, JH Kim, JP Taylor, TE Lloyd, ...
Human Molecular Genetics 20 (13), 2510, 2011
2302011
RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
JG Daigle, NA Lanson Jr, RB Smith, I Casci, A Maltare, J Monaghan, ...
Human molecular genetics 22 (6), 1193-1205, 2013
2242013
Autophagy dysregulation in ALS: when protein aggregates get out of hand
N Ramesh, UB Pandey
Frontiers in molecular neuroscience 10, 263, 2017
1852017
HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration
UB Pandey, Y Batlevi, EH Baehrecke, JP Taylor
Autophagy 3 (6), 643, 2007
1492007
Stress granules at the intersection of autophagy and ALS
Z Monahan, F Shewmaker, UB Pandey
Brain research 1649, 189-200, 2016
1352016
RNP-granule assembly via ataxin-2 disordered domains is required for long-term memory and neurodegeneration
B Bakthavachalu, J Huelsmeier, IP Sudhakaran, J Hillebrand, A Singh, ...
Neuron 98 (4), 754-766. e4, 2018
1122018
Histone Deacetylases Suppress CGG Repeat–Induced Neurodegeneration Via Transcriptional Silencing in Models of Fragile X Tremor Ataxia Syndrome
PK Todd, SY Oh, A Krans, UB Pandey, NA Di Prospero, KT Min, JP Taylor, ...
PLoS Genetics 6 (12), e1001240, 2010
1072010
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy
L Marrone, HCA Drexler, J Wang, P Tripathi, T Distler, P Heisterkamp, ...
Acta neuropathologica 138, 67-84, 2019
1062019
Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy
C Scaramuzzino, I Casci, S Parodi, PMJ Lievens, MJ Polanco, C Milioto, ...
Neuron 85 (1), 88-100, 2015
1012015
A fruitful endeavor: modeling ALS in the fruit fly
I Casci, UB Pandey
Brain research 1607, 47-74, 2015
1002015
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo
C Scaramuzzino, J Monaghan, C Milioto, NA Lanson Jr, A Maltare, ...
PloS one 8 (4), e61576, 2013
1002013
Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models
EN Anderson, L Gochenaur, A Singh, R Grant, K Patel, S Watkins, JY Wu, ...
Human molecular genetics 27 (8), 1366-1381, 2018
972018
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