Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies N Boeckx, R Koukakis, KO De Beeck, C Rolfo, G Van Camp, S Siena, ... Annals of Oncology 28 (8), 1862-1868, 2017 | 216 | 2017 |
Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell KO de Beeck, J Schacht, G Van Camp Hearing research 281 (1-2), 18-27, 2011 | 181 | 2011 |
The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein KO De Beeck, G Van Camp, S Thys, N Cools, I Callebaut, K Vrijens, ... European Journal of Human Genetics 19 (9), 965-973, 2011 | 129 | 2011 |
Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1 T Vandamme, M Peeters, F Dogan, P Pauwels, E Van Assche, M Beyens, ... Journal of molecular endocrinology 54 (2), 137-147, 2015 | 108 | 2015 |
The genetic landscape of malignant pleural mesothelioma: results from massively parallel sequencing M Hylebos, G Van Camp, JP Van Meerbeeck, KO De Beeck Journal of Thoracic Oncology 11 (10), 1615-1626, 2016 | 95 | 2016 |
Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer L Croes, M Beyens, E Fransen, J Ibrahim, W Vanden Berghe, A Suls, ... Clinical epigenetics 10, 1-13, 2018 | 93 | 2018 |
Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors T Vandamme, M Beyens, KO de Beeck, F Dogan, PM van Koetsveld, ... British journal of cancer 114 (6), 650-658, 2016 | 87 | 2016 |
Pharmacological Levels of Withaferin A (Withania somnifera) Trigger Clinically Relevant Anticancer Effects Specific to Triple Negative Breast Cancer Cells K Szarc vel Szic, K Op de Beeck, D Ratman, A Wouters, IM Beck, ... PloS one 9 (2), e87850, 2014 | 78 | 2014 |
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer C Deben, A Wouters, KO de Beeck, J van Den Bossche, J Jacobs, ... Oncotarget 6 (26), 22666, 2015 | 77 | 2015 |
DFNA5, a gene involved in hearing loss and cancer: a review K Op de Beeck, L Van Laer, G Van Camp Annals of Otology, Rhinology & Laryngology 121 (3), 197-207, 2012 | 75 | 2012 |
GSDME and its role in cancer: From behind the scenes to the front of the stage E De Schutter, L Croes, J Ibrahim, P Pauwels, K Op de Beeck, ... International Journal of Cancer 148 (12), 2872-2883, 2021 | 67 | 2021 |
Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins C Boeckx, KO de Beeck, A Wouters, V Deschoolmeester, R Limame, ... Cancer letters 354 (2), 365-377, 2014 | 67 | 2014 |
Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway K Heyninck, L Sabbe, CS Chirumamilla, KS vel Szic, P Vander Veken, ... Biochemical pharmacology 109, 48-61, 2016 | 65 | 2016 |
Krüppel-like factors in cancer progression: three fingers on the steering wheel R Limame, KO de Beeck, F Lardon, O De Wever, P Pauwels Oncotarget 5 (1), 29, 2014 | 65 | 2014 |
Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer J Ibrahim, K Op de Beeck, E Fransen, L Croes, M Beyens, A Suls, ... Cancer medicine 8 (5), 2133-2145, 2019 | 55 | 2019 |
The predictive value of primary tumor location in patients with metastatic colorectal cancer: a systematic review N Boeckx, K Janssens, G Van Camp, M Rasschaert, K Papadimitriou, ... Critical Reviews in Oncology/Hematology 121, 1-10, 2018 | 55 | 2018 |
APR-246 (PRIMA-1MET) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines C Deben, F Lardon, A Wouters, KO de Beeck, J Van den Bossche, ... Cancer letters 375 (2), 313-322, 2016 | 55 | 2016 |
The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways S Van Rossom, K Op de Beeck, V Hristovska, J Winderickx, G Van Camp Frontiers in cellular neuroscience 9, 231, 2015 | 48 | 2015 |
Effect of primary tumor location on second-or later-line treatment outcomes in patients with RAS wild-type metastatic colorectal cancer and all treatment lines in patients with … N Boeckx, R Koukakis, KO de Beeck, C Rolfo, G Van Camp, S Siena, ... Clinical colorectal cancer 17 (3), 170-178. e3, 2018 | 47 | 2018 |
DFNA5 promoter methylation a marker for breast tumorigenesis L Croes, KO de Beeck, P Pauwels, WV Berghe, M Peeters, E Fransen, ... Oncotarget 8 (19), 31948, 2017 | 43 | 2017 |