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Ken Op de Beeck
Ken Op de Beeck
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Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies
N Boeckx, R Koukakis, KO De Beeck, C Rolfo, G Van Camp, S Siena, ...
Annals of Oncology 28 (8), 1862-1868, 2017
2172017
Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell
KO de Beeck, J Schacht, G Van Camp
Hearing research 281 (1-2), 18-27, 2011
1822011
The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein
KO De Beeck, G Van Camp, S Thys, N Cools, I Callebaut, K Vrijens, ...
European Journal of Human Genetics 19 (9), 965-973, 2011
1302011
Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1
T Vandamme, M Peeters, F Dogan, P Pauwels, E Van Assche, M Beyens, ...
Journal of molecular endocrinology 54 (2), 137-147, 2015
1082015
The genetic landscape of malignant pleural mesothelioma: results from massively parallel sequencing
M Hylebos, G Van Camp, JP Van Meerbeeck, KO De Beeck
Journal of Thoracic Oncology 11 (10), 1615-1626, 2016
962016
Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer
L Croes, M Beyens, E Fransen, J Ibrahim, W Vanden Berghe, A Suls, ...
Clinical epigenetics 10, 1-13, 2018
942018
Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors
T Vandamme, M Beyens, KO de Beeck, F Dogan, PM van Koetsveld, ...
British journal of cancer 114 (6), 650-658, 2016
872016
Pharmacological Levels of Withaferin A (Withania somnifera) Trigger Clinically Relevant Anticancer Effects Specific to Triple Negative Breast Cancer Cells
K Szarc vel Szic, K Op de Beeck, D Ratman, A Wouters, IM Beck, ...
PloS one 9 (2), e87850, 2014
782014
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer
C Deben, A Wouters, KO de Beeck, J van Den Bossche, J Jacobs, ...
Oncotarget 6 (26), 22666, 2015
772015
DFNA5, a gene involved in hearing loss and cancer: a review
K Op de Beeck, L Van Laer, G Van Camp
Annals of Otology, Rhinology & Laryngology 121 (3), 197-207, 2012
752012
GSDME and its role in cancer: From behind the scenes to the front of the stage
E De Schutter, L Croes, J Ibrahim, P Pauwels, K Op de Beeck, ...
International Journal of Cancer 148 (12), 2872-2883, 2021
672021
Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins
C Boeckx, KO de Beeck, A Wouters, V Deschoolmeester, R Limame, ...
Cancer letters 354 (2), 365-377, 2014
672014
Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway
K Heyninck, L Sabbe, CS Chirumamilla, KS vel Szic, P Vander Veken, ...
Biochemical pharmacology 109, 48-61, 2016
662016
Krüppel-like factors in cancer progression: three fingers on the steering wheel
R Limame, KO de Beeck, F Lardon, O De Wever, P Pauwels
Oncotarget 5 (1), 29, 2014
652014
Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer
J Ibrahim, K Op de Beeck, E Fransen, L Croes, M Beyens, A Suls, ...
Cancer medicine 8 (5), 2133-2145, 2019
552019
The predictive value of primary tumor location in patients with metastatic colorectal cancer: a systematic review
N Boeckx, K Janssens, G Van Camp, M Rasschaert, K Papadimitriou, ...
Critical Reviews in Oncology/Hematology 121, 1-10, 2018
552018
APR-246 (PRIMA-1MET) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines
C Deben, F Lardon, A Wouters, KO de Beeck, J Van den Bossche, ...
Cancer letters 375 (2), 313-322, 2016
552016
The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways
S Van Rossom, K Op de Beeck, V Hristovska, J Winderickx, G Van Camp
Frontiers in cellular neuroscience 9, 231, 2015
482015
Effect of primary tumor location on second-or later-line treatment outcomes in patients with RAS wild-type metastatic colorectal cancer and all treatment lines in patients with …
N Boeckx, R Koukakis, KO de Beeck, C Rolfo, G Van Camp, S Siena, ...
Clinical colorectal cancer 17 (3), 170-178. e3, 2018
472018
DFNA5 promoter methylation a marker for breast tumorigenesis
L Croes, KO de Beeck, P Pauwels, WV Berghe, M Peeters, E Fransen, ...
Oncotarget 8 (19), 31948, 2017
452017
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Artikelen 1–20