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Denis Franchimont
Denis Franchimont
Geverifieerd e-mailadres voor erasme.ulb.ac.be
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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
51342012
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, ...
Nature genetics 40 (8), 955-962, 2008
32242008
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ...
Nature genetics 42 (12), 1118-1125, 2010
31322010
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ...
Nature genetics 43 (3), 246-252, 2011
17012011
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis
D Franchimont, S Vermeire, H El Housni, M Pierik, K Van Steen, T Gustot, ...
Gut 53 (7), 987-992, 2004
7932004
Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
J Galon, D Franchimont, N Hiroi, G Frey, A Boettner, M Ehrhart-Bornstein, ...
The FASEB journal 16 (1), 61-71, 2002
7562002
Novel Crohn Disease Locus Identified by Genome-Wide Association Maps to a Gene Desert on 5p13.1 and Modulates Expression of PTGER4
C Libioulle, E Louis, S Hansoul, C Sandor, F Farnir, D Franchimont, ...
PLoS genetics 3 (4), e58, 2007
6842007
Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial
D Laharie, A Bourreille, J Branche, M Allez, Y Bouhnik, J Filippi, F Zerbib, ...
The Lancet 380 (9857), 1909-1915, 2012
6432012
International IBD Genetics Consortium (IIBDGC). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ...
Nature 491 (7422), 119-124, 2012
6212012
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
AC Villani, M Lemire, G Fortin, E Louis, MS Silverberg, C Collette, N Baba, ...
Nature genetics 41 (1), 71-76, 2009
5762009
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
S Buch, F Stickel, E Trepo, M Way, A Herrmann, HD Nischalke, M Brosch, ...
Nature genetics 47 (12), 1443-1448, 2015
5432015
Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies
D Franchimont
Annals of the New York Academy of Sciences 1024 (1), 124-137, 2004
5012004
Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled …
BG Feagan, WJ Sandborn, G D'Haens, J Panés, A Kaser, M Ferrante, ...
The Lancet 389 (10080), 1699-1709, 2017
4552017
Stratification of pancreatic ductal adenocarcinomas based on tumor and microenvironment features
F Puleo, R Nicolle, Y Blum, J Cros, L Marisa, P Demetter, E Quertinmont, ...
Gastroenterology 155 (6), 1999-2013. e3, 2018
4282018
Multicenter randomized-controlled clinical trial of probiotics (Lactobacillus johnsonii, LA1) on early endoscopic recurrence of Crohn's disease after ileo-caecal …
A Van Gossum, O Dewit, E Louis, G de Hertogh, F Baert, F Fontaine, ...
Inflammatory bowel diseases 13 (2), 135-142, 2007
3742007
Predicting relapse in Crohn’s disease: a biopsychosocial model
A Bitton, PL Dobkin, MD Edwardes, MJ Sewitch, JB Meddings, S Rawal, ...
Gut 57 (10), 1386-1392, 2008
3352008
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
3292015
Results from the 2nd Scientific Workshop of the ECCO (I): Impact of mucosal healing on the course of inflammatory bowel disease
L Peyrin-Biroulet, M Ferrante, F Magro, S Campbell, D Franchimont, ...
Journal of Crohn's and Colitis 5 (5), 477-483, 2011
3292011
Infliximab reduces endoscopic, but not clinical, recurrence of Crohn’s disease after ileocolonic resection
M Regueiro, BG Feagan, B Zou, J Johanns, MA Blank, M Chevrier, ...
Gastroenterology 150 (7), 1568-1578, 2016
3182016
Tumor necrosis factor α decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor
D Franchimont, H Martens, MT Hagelstein, E Louis, W Dewe, ...
The Journal of Clinical Endocrinology & Metabolism 84 (8), 2834-2839, 1999
3161999
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