Nicotine induces cell proliferation, invasion and epithelial‐mesenchymal transition in a variety of human cancer cell lines P Dasgupta, W Rizwani, S Pillai, R Kinkade, M Kovacs, S Rastogi, ... International Journal of Cancer 124 (1), 36-45, 2009 | 417 | 2009 |
Nicotine induces cell proliferation by β-arrestin–mediated activation of Src and Rb–Raf-1 pathways P Dasgupta, S Rastogi, S Pillai, D Ordonez-Ercan, M Morris, E Haura, ... The Journal of clinical investigation 116 (8), 2208-2217, 2006 | 369 | 2006 |
Causes, consequences, and therapy of tumors acidosis SR Pillai, M Damaghi, Y Marunaka, EP Spugnini, S Fais, RJ Gillies Cancer and Metastasis Reviews 38, 205-222, 2019 | 244 | 2019 |
Nicotinic acetylcholine receptor signaling in tumor growth and metastasis S Singh, S Pillai, S Chellappan Journal of oncology 2011, 2011 | 151 | 2011 |
Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb–Raf-1 interaction as a novel target for metastatic disease JL Johnson, S Pillai, D Pernazza, SM Sebti, NJ Lawrence, SP Chellappan Cancer research 72 (2), 516-526, 2012 | 106 | 2012 |
ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors P Dasgupta, W Rizwani, S Pillai, R Davis, S Banerjee, K Hug, M Lloyd, ... Journal of the National Cancer Institute 103 (4), 317-333, 2011 | 106 | 2011 |
T-cells produce acidic niches in lymph nodes to suppress their own effector functions H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ... Nature communications 11 (1), 4113, 2020 | 103 | 2020 |
The Rb–E2F transcriptional regulatory pathway in tumor angiogenesis and metastasis C Schaal, S Pillai, SP Chellappan Advances in cancer research 121, 147-182, 2014 | 96 | 2014 |
Tank Binding Kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis S Pillai, J Nguyen, J Johnson, E Haura, D Coppola, S Chellappan Nature Communications 6, 2015 | 94 | 2015 |
ID1 facilitates the growth and metastasis of non-small cell lung cancer in response to nicotinic acetylcholine receptor and epidermal growth factor receptor signaling S Pillai, W Rizwani, X Li, B Rawal, S Nair, MJ Schell, G Bepler, E Haura, ... Molecular and cellular biology 31 (14), 3052-3067, 2011 | 85 | 2011 |
Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma JG Trevino, S Pillai, S Kunigal, S Singh, WJ Fulp, BA Centeno, ... Neoplasia 14 (12), 1102-1114, 2012 | 82 | 2012 |
β-Arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial–mesenchymal transition S Pillai, J Trevino, B Rawal, S Singh, M Kovacs, X Li, M Schell, E Haura, ... Cancer research 75 (6), 1009-1020, 2015 | 81 | 2015 |
Regulation of vascular endothelial growth factor receptors by Rb and E2F1: role of acetylation S Pillai, M Kovacs, S Chellappan Cancer research 70 (12), 4931-4940, 2010 | 79 | 2010 |
Genetic and biochemical alterations in non-small cell lung cancer JL Johnson, S Pillai, SP Chellappan Biochemistry research international 2012, 2012 | 69 | 2012 |
TNF-α-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes R Davis, S Pillai, N Lawrence, SP Chellappan Cell Cycle 11 (1), 109-118, 2012 | 58 | 2012 |
A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice R Kinkade, P Dasgupta, A Carie, D Pernazza, M Carless, S Pillai, ... Cancer research 68 (10), 3810-3818, 2008 | 58 | 2008 |
GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion J Sun, H He, S Pillai, Y Xiong, S Challa, L Xu, S Chellappan, S Yang Journal of Biological Chemistry 288 (52), 36971-36982, 2013 | 55 | 2013 |
α7 nicotinic acetylcholine receptor subunit in angiogenesis and epithelial to mesenchymal transition S Pillai, S Chellappan Current drug targets 13 (5), 671-679, 2012 | 55 | 2012 |
Multiparametric MRI and coregistered histology identify tumor habitats in breast cancer mouse models BV Jardim-Perassi, S Huang, W Dominguez-Viqueira, J Poleszczuk, ... Cancer research 79 (15), 3952-3964, 2019 | 53 | 2019 |
Nicotinic acetylcholine receptors induce c-Kit ligand/stem cell factor and promote stemness in an ARRB1/β-arrestin-1 dependent manner in NSCLC D Perumal, S Pillai, J Nguyen, C Schaal, D Coppola, SP Chellappan Oncotarget 5 (21), 10486, 2014 | 45 | 2014 |