| Role of PFKFB3-driven glycolysis in vessel sprouting K De Bock, M Georgiadou, S Schoors, A Kuchnio, BW Wong, ... Cell 154 (3), 651-663, 2013 | 1337 | 2013 |
| Tumour hypoxia causes DNA hypermethylation by reducing TET activity B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ... Nature 537 (7618), 63-68, 2016 | 579 | 2016 |
| Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 552 | 2016 |
| Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis S Schoors, K De Bock, AR Cantelmo, M Georgiadou, B Ghesquière, ... Cell metabolism 19 (1), 37-48, 2014 | 525 | 2014 |
| A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours B Beck, G Driessens, S Goossens, KK Youssef, A Kuchnio, A Caauwe, ... Nature 478 (7369), 399-403, 2011 | 522 | 2011 |
| Metabolism of stromal and immune cells in health and disease B Ghesquière, BW Wong, A Kuchnio, P Carmeliet Nature 511 (7508), 167-176, 2014 | 465 | 2014 |
| Tumor vessel normalization by chloroquine independent of autophagy H Maes, A Kuchnio, A Peric, S Moens, K Nys, K De Bock, A Quaegebeur, ... Cancer cell 26 (2), 190-206, 2014 | 416 | 2014 |
| Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes BW Wong, A Kuchnio, U Bruning, P Carmeliet Trends in biochemical sciences 38 (1), 3-11, 2013 | 162 | 2013 |
| Glycolytic regulation of cell rearrangement in angiogenesis B Cruys, BW Wong, A Kuchnio, D Verdegem, AR Cantelmo, LC Conradi, ... Nature communications 7 (1), 12240, 2016 | 148 | 2016 |
| Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism F Morfoisse, A Kuchnio, C Frainay, A Gomez-Brouchet, MB Delisle, ... Cell reports 6 (1), 155-167, 2014 | 144 | 2014 |
| The Fragile X Protein binds m RNA s involved in cancer progression and modulates metastasis formation R Lucá, M Averna, F Zalfa, M Vecchi, F Bianchi, GL Fata, F Del Nonno, ... EMBO molecular medicine 5 (10), 1523-1536, 2013 | 113 | 2013 |
| Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity JR Hernandez-Fernaud, E Ruengeler, A Casazza, LJ Neilson, E Pulleine, ... Nature communications 8 (1), 14206, 2017 | 100 | 2017 |
| The cancer cell oxygen sensor PHD2 promotes metastasis via activation of cancer-associated fibroblasts A Kuchnio, S Moens, U Bruning, K Kuchnio, B Cruys, B Thienpont, ... Cell reports 12 (6), 992-1005, 2015 | 83 | 2015 |
| Chloroquine anticancer activity is mediated by autophagy-independent effects on the tumor vasculature H Maes, A Kuchnio, P Carmeliet, P Agostinis Molecular & cellular oncology 3 (1), e970097, 2016 | 34 | 2016 |
| Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice F Heindryckx, A Kuchnio, C Casteleyn, S Coulon, K Olievier, I Colle, ... Journal of hepatology 57 (1), 61-68, 2012 | 26 | 2012 |
| How to teach an old dog new tricks: autophagy-independent action of chloroquine on the tumor vasculature H Maes, A Kuchnio, P Carmeliet, P Agostinis Autophagy 10 (11), 2082-2084, 2014 | 21 | 2014 |
| Synthesis of novel aryl (heteroaryl) sulfonyl ureas of possible biological interest F Sączewski, A Kuchnio, M Samsel, M Łobocka, A Kiedrowska, ... Molecules 15 (3), 1113-1126, 2010 | 12 | 2010 |
| The PHD2 oxygen sensor paves the way to metastasis A Kuchnio, M Dewerchin, P Carmeliet Oncotarget 6 (34), 35149-50, 2015 | 11 | 2015 |
| Characterization of JNJ-80948543, a novel CD79bxCD20xCD3 trispecific T-cell redirecting antibody for the treatment of b-cell non-Hodgkin lymphoma A Kuchnio, D Yang, N Vloemans, C Lowenstein, I Cornelissen, R Amorim, ... Blood 140 (Supplement 1), 3105-3106, 2022 | 8 | 2022 |
| Synthesis, Cytotoxicity Testing, and Structure–Activity Relationships of Novel 6‐Chloro‐7‐(4‐phenylimino‐4H‐3,1‐benzoxazin‐2‐yl)‐3‐(substituted)‐1,4,2 … E Pomarnacka, A Kornicka, A Kuchnio, M Heinrichs, R Grünert, ... Archiv der Pharmazie 344 (7), 431-441, 2011 | 3 | 2011 |
