| In situ click chemistry: enzyme inhibitors made to their own specifications R Manetsch, A Krasiński, Z Radić, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 126 (40), 12809-12818, 2004 | 607 | 2004 |
| In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors A Krasiński, Z Radić, R Manetsch, J Raushel, P Taylor, KB Sharpless, ... Journal of the American Chemical Society 127 (18), 6686-6692, 2005 | 468 | 2005 |
| Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 246 | 2013 |
| In situ click chemistry: a powerful means for lead discovery KB Sharpless, R Manetsch Expert Opinion on Drug Discovery 1 (6), 525-538, 2006 | 242 | 2006 |
| Endochin Optimization: Structure−Activity and Structure−Property Relationship Studies of 3-Substituted 2-Methyl-4(1H)-quinolones with Antimalarial Activity RM Cross, A Monastyrskyi, TS Mutka, JN Burrows, DE Kyle, R Manetsch Journal of medicinal chemistry 53 (19), 7076-7094, 2010 | 138 | 2010 |
| Antibacterial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines KS Van Horn, WN Burda, R Fleeman, LN Shaw, R Manetsch Journal of Medicinal Chemistry 57 (7), 3075-3093, 2014 | 107 | 2014 |
| Metal‐free cross‐dehydrogenative coupling (CDC): molecular iodine as a versatile catalyst/reagent for CDC reactions PT Parvatkar, R Manetsch, BK Banik Chemistry–An Asian Journal 14 (1), 6-30, 2019 | 103 | 2019 |
| Bcl-XL-Templated Assembly of Its Own Protein−Protein Interaction Modulator from Fragments Decorated with Thio Acids and Sulfonyl Azides X Hu, J Sun, HG Wang, R Manetsch Journal of the American Chemical Society 130 (42), 13820-13821, 2008 | 92 | 2008 |
| Antileishmanial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines KS Van Horn, X Zhu, T Pandharkar, S Yang, B Vesely, M Vanaerschot, ... Journal of medicinal chemistry 57 (12), 5141-5156, 2014 | 83 | 2014 |
| Optimization of 1, 2, 3, 4-tetrahydroacridin-9 (10H)-ones as antimalarials utilizing structure–activity and structure–property relationships RM Cross, JR Maignan, TS Mutka, L Luong, J Sargent, DE Kyle, ... American Chemical Society, 2011 | 83 | 2011 |
| Kinetic target-guided synthesis X Hu, R Manetsch Chemical Society Reviews 39 (4), 1316-1324, 2010 | 78 | 2010 |
| Synthesis, Antimalarial Activity, and Structure–Activity Relationship of 7-(2-Phenoxyethoxy)-4(1H)-quinolones RM Cross, NK Namelikonda, TS Mutka, L Luong, DE Kyle, R Manetsch Journal of medicinal chemistry 54 (24), 8321-8327, 2011 | 71 | 2011 |
| Divergent route to access structurally diverse 4-quinolones via mono or sequential cross-couplings RM Cross, R Manetsch The Journal of Organic Chemistry 75 (24), 8654-8657, 2010 | 71 | 2010 |
| Screening of Protein–Protein Interaction Modulators via Sulfo-Click Kinetic Target-Guided Synthesis SS Kulkarni, X Hu, K Doi, HG Wang, R Manetsch ACS chemical biology 6 (7), 724-732, 2011 | 64 | 2011 |
| Metal-Free Arylation of Ethyl Acetoacetate with Hypervalent Diaryliodonium Salts: An Immediate Access to Diverse 3-Aryl-4(1H)-Quinolones A Monastyrskyi, NK Namelikonda, R Manetsch The Journal of organic chemistry 80 (5), 2513-2520, 2015 | 59 | 2015 |
| Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium RM Cross, DL Flanigan, A Monastyrskyi, AN LaCrue, FE Sáenz, ... Journal of Medicinal Chemistry 57 (21), 8860-8879, 2014 | 42 | 2014 |
| 4(1H)-Quinolones with Liver Stage Activity against Plasmodium berghei AN LaCrue, FE Sáenz, RM Cross, KO Udenze, A Monastyrskyi, S Stein, ... Antimicrobial agents and chemotherapy 57 (1), 417-424, 2013 | 42 | 2013 |
| A catalytic antibody against a tocopherol cyclase inhibitor R Manetsch, L Zheng, MT Reymond, WD Woggon, JL Reymond Chemistry–A European Journal 10 (10), 2487-2506, 2004 | 41 | 2004 |
| A simple base-mediated amidation of aldehydes with azides SS Kulkarni, X Hu, R Manetsch Chemical communications 49 (12), 1193-1195, 2013 | 40 | 2013 |
| SAR refinement of antileishmanial N2, N4-disubstituted quinazoline-2, 4-diamines X Zhu, KS Van Horn, MM Barber, S Yang, MZ Wang, R Manetsch, ... Bioorganic & medicinal chemistry 23 (16), 5182-5189, 2015 | 36 | 2015 |
Dennis E. KyleDirector, Center for Tropical and Emerging Global Diseases, University of GeorgiaVerified email at uga.edu
