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Jeffrey Mewburn
Jeffrey Mewburn
Geverifieerd e-mailadres voor queensu.ca
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Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine
KJ Dunham-Snary, D Wu, EA Sykes, A Thakrar, LRG Parlow, JD Mewburn, ...
Chest 151 (1), 181-192, 2017
4172017
Canine hindlimb blood flow and O2 uptake after inhibition of EDRF/NO synthesis
CE King, MJ Melinyshyn, JD Mewburn, SE Curtis, MJ Winn, SM Cain, ...
Journal of applied physiology 76 (3), 1166-1171, 1994
1371994
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype
Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ...
American journal of respiratory and critical care medicine 195 (4), 515-529, 2017
1352017
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension …
KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ...
Circulation 138 (3), 287-304, 2018
1232018
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ...
Journal of molecular medicine 95, 381-393, 2017
992017
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension
F Potus, MW Pauciulo, EK Cook, N Zhu, A Hsieh, CL Welch, Y Shen, ...
Circulation 141 (24), 1986-2000, 2020
942020
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial …
L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ...
Circulation research 126 (12), 1723-1745, 2020
912020
Histones link inflammation and thrombosis through the induction of Weibel–Palade body exocytosis
A Michels, S Albánez, J Mewburn, K Nesbitt, TJ Gould, PC Liaw, ...
Journal of Thrombosis and Haemostasis 14 (11), 2274-2286, 2016
842016
Sperm‐borne protein, PAWP, initiates zygotic development in Xenopus laevis by eliciting intracellular calcium release
M Aarabi, Z Qin, W Xu, J Mewburn, R Oko
Molecular Reproduction and Development: Incorporating Gamete Research 77 (3 …, 2010
822010
Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction
KJ Dunham-Snary, D Wu, F Potus, EA Sykes, JD Mewburn, RL Charles, ...
Circulation research 124 (12), 1727-1746, 2019
782019
Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
D Wu, A Dasgupta, KH Chen, M Neuber‐Hess, J Patel, TE Hurst, ...
The FASEB Journal 34 (1), 1447-1464, 2020
742020
Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension
L Tian, F Potus, D Wu, A Dasgupta, KH Chen, J Mewburn, P Lima, ...
Frontiers in physiology 9, 369543, 2018
712018
Cysteinyl leukotriene 2 receptor‐mediated vascular permeability via transendothelial vesicle transport
MPW Moos, JD Mewburn, FWK Kan, S Ishii, M Abe, K Sakimura, ...
The FASEB Journal 22 (12), 4352-4362, 2008
562008
Renal and cardiovascular characterization of COX-2 knockdown mice
F Seta, AD Chung, PV Turner, JD Mewburn, Y Yu, CD Funk
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009
502009
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions
M Golder, CM Pruss, C Hegadorn, J Mewburn, K Laverty, K Sponagle, ...
Blood, The Journal of the American Society of Hematology 115 (23), 4862-4869, 2010
482010
Endogenously Generated Omega‐3 Fatty Acids Attenuate Vascular Inflammation and Neointimal Hyperplasia by Interaction With Free Fatty Acid Receptor 4 in Mice
X Li, LL Ballantyne, X Che, JD Mewburn, JX Kang, RM Barkley, ...
Journal of the American Heart Association 4 (4), e001856, 2015
432015
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer
D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ...
Free Radical Biology and Medicine 170, 150-178, 2021
382021
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling
AL Theilmann, LG Hawke, LR Hilton, MKM Whitford, DV Cole, JL Mackeil, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 40 (11), 2605-2618, 2020
372020
Mitochondria in human neutrophils mediate killing of Staphylococcus aureus
KJ Dunham-Snary, BGJ Surewaard, JD Mewburn, RET Bentley, AY Martin, ...
Redox biology 49, 102225, 2022
352022
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation
Y Shida, N Rydz, D Stegner, C Brown, J Mewburn, K Sponagle, ...
Blood, The Journal of the American Society of Hematology 124 (11), 1799-1807, 2014
352014
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