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David G. Kugler
David G. Kugler
Cartography Biosciences
Geverifieerd e-mailadres voor cartography.bio
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Cutting edge: interleukin 17 signals through a heteromeric receptor complex
D Toy, D Kugler, M Wolfson, TV Bos, J Gurgel, J Derry, J Tocker, ...
The Journal of Immunology 177 (1), 36-39, 2006
7082006
Cutting edge: caspase-1 independent IL-1β production is critical for host resistance to Mycobacterium tuberculosis and does not require TLR signaling in vivo
KD Mayer-Barber, DL Barber, K Shenderov, SD White, MS Wilson, ...
The Journal of Immunology 184 (7), 3326-3330, 2010
5762010
Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
H Blumberg, H Dinh, ES Trueblood, J Pretorius, D Kugler, N Weng, ...
The Journal of experimental medicine 204 (11), 2603-2614, 2007
4332007
Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities
EA Rickel, LA Siegel, BRP Yoon, JB Rottman, DG Kugler, DA Swart, ...
The journal of immunology 181 (6), 4299-4310, 2008
3982008
IL-10 production by CD4+ effector T cells: a mechanism for self-regulation
D Jankovic, DG Kugler, A Sher
Mucosal immunology 3 (3), 239-246, 2010
2652010
miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression
TM Escobar, C Kanellopoulou, DG Kugler, G Kilaru, CK Nguyen, ...
Immunity 40 (6), 865-879, 2014
2082014
Anti–B-cell maturation antigen chimeric antigen receptor T cell function against multiple myeloma is enhanced in the presence of lenalidomide
M Works, N Soni, C Hauskins, C Sierra, A Baturevych, JC Jones, W Curtis, ...
Molecular cancer therapeutics 18 (12), 2246-2257, 2019
732019
β8 integrin expression and activation of TGF-β by intestinal dendritic cells are determined by both tissue microenvironment and cell lineage
M Boucard-Jourdin, D Kugler, ML Endale Ahanda, S This, J De Calisto, ...
The Journal of immunology 197 (5), 1968-1978, 2016
632016
CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection
DG Kugler, PR Mittelstadt, JD Ashwell, A Sher, D Jankovic
Journal of Experimental Medicine 210 (10), 1919-1927, 2013
582013
Inflammatory Th17 cells express integrin αvβ3 for pathogenic function
F Du, AV Garg, K Kosar, S Majumder, DG Kugler, GH Mir, M Maggio, ...
Cell reports 16 (5), 1339-1351, 2016
442016
Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes
DG Kugler, FA Flomerfelt, DL Costa, K Laky, O Kamenyeva, PR Mittelstadt, ...
Journal of Experimental Medicine 213 (13), 3041-3056, 2016
352016
Expamers: a new technology to control T cell activation
MP Poltorak, P Graef, C Tschulik, M Wagner, V Cletiu, S Dreher, B Borjan, ...
Scientific Reports 10 (1), 17832, 2020
252020
Processes for generating engineered cells and compositions thereof
M Westoby, AW Briggs, DG Kugler, L Germeroth, C Stemberger, ...
US Patent App. 17/267,000, 2021
42021
Combination of a cell therapy and an immunomodulatory compound
M Ports, M Works, O Baturevych, R Salmon, RJ Hause Jr, TG Johnstone, ...
32020
217 Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25 induced activities
EA Rickel, LA Siegel, BRP Yoon, J Rottman, D Kugler, D Swart, P Anders, ...
Cytokine 3 (43), 291, 2008
32008
Lenalidomide enhances anti-bcma chimeric antigen receptor T cell function against multiple myeloma
M Works, N Soni, C Hauskins, C Sierra, A Baturevych, J Jones, W Curtis, ...
Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 1794 …, 2017
22017
Mechanisms that regulate Th1-mediated immunopathology during Toxoplasma gondii infection
DG Kugler
The Johns Hopkins University, 2013
22013
Caspase-1 independent IL-1β Production is critical for MyD88-mediated host resistance to Mycobacterium tuberculosis (42.13)
K Mayer-Barber, D Barber, K Shenderov, S White, M Wilson, A Cheever, ...
The Journal of Immunology 184 (1_Supplement), 42.13-42.13, 2010
12010
P105 NEX-T CD19 chimeric antigen receptor (CAR) T-cell therapy CC-97540 (BMS-986353): Preclinical and translational evidence of deep B-cell depletion suitable for study in …
G Schett, T Feldman, J Abramson, B Hu, F Müller, A Koegel, J Thorpe, ...
Lupus Science & Medicine 11 (Suppl 1), 2024
2024
Kombination af en celleterapi og en immunomodulerende forbindelse
M Ports, M Works, O Baturevych, R Salmon, RJ Hause Jr, TG Johnstone, ...
2024
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