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Michael Holinstat
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Normal platelet function
M Holinstat
Cancer and Metastasis Reviews 36, 195-198, 2017
4542017
RhoA interaction with inositol 1, 4, 5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry: role in signaling increased endothelial permeability
D Mehta, GU Ahmmed, BC Paria, M Holinstat, T Voyno-Yasenetskaya, ...
Journal of Biological Chemistry 278 (35), 33492-33500, 2003
2442003
Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
LM Simon, LC Edelstein, S Nagalla, AB Woodley, ES Chen, X Kong, L Ma, ...
Blood, The Journal of the American Society of Hematology 123 (16), e37-e45, 2014
2422014
Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1
JN McLaughlin, L Shen, M Holinstat, JD Brooks, E DiBenedetto, ...
Journal of biological chemistry 280 (26), 25048-25059, 2005
2322005
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c
LC Edelstein, LM Simon, RT Montoya, M Holinstat, ES Chen, A Bergeron, ...
Nature medicine 19 (12), 1609-1616, 2013
2282013
Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability
M Holinstat, N Knezevic, M Broman, AM Samarel, AB Malik, D Mehta
Journal of Biological Chemistry 281 (4), 2296-2305, 2006
2042006
Protein kinase Cα-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement
M Holinstat, D Mehta, T Kozasa, RD Minshall, AB Malik
Journal of Biological Chemistry 278 (31), 28793-28798, 2003
2002003
Protein kinase Cα-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement
M Holinstat, D Mehta, T Kozasa, RD Minshall, AB Malik
Journal of Biological Chemistry 278 (31), 28793-28798, 2003
2002003
Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells
GU Ahmmed, D Mehta, S Vogel, M Holinstat, BC Paria, C Tiruppathi, ...
Journal of Biological Chemistry 279 (20), 20941-20949, 2004
1992004
Anti-inflammatory ω-3 endocannabinoid epoxides
DR McDougle, JE Watson, AA Abdeen, R Adili, MP Caputo, JE Krapf, ...
Proceedings of the National Academy of Sciences 114 (30), E6034-E6043, 2017
1782017
Platelet signaling and disease: targeted therapy for thrombosis and other related diseases
J Yeung, W Li, M Holinstat
Pharmacological reviews 70 (3), 526-548, 2018
1742018
PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation
M Holinstat, B Voss, ML Bilodeau, JN McLaughlin, J Cleator, HE Hamm
Journal of Biological Chemistry 281 (36), 26665-26674, 2006
1412006
Micro RNA s in platelet production and activation
LC Edelstein, SE McKenzie, C Shaw, MA Holinstat, SP Kunapuli, PF Bray
Journal of Thrombosis and Haemostasis 11, 340-350, 2013
1232013
Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race
LC Edelstein, LM Simon, CR Lindsay, X Kong, R Teruel-Montoya, ...
Blood, The Journal of the American Society of Hematology 124 (23), 3450-3458, 2014
1192014
PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis
B Voss, JN McLaughlin, M Holinstat, R Zent, HE Hamm
Molecular pharmacology 71 (5), 1399-1406, 2007
1112007
Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function
D Mehta, C Tiruppathi, R Sandoval, RD Minshall, M Holinstat, AB Malik
The Journal of physiology 539 (3), 779-789, 2002
1062002
Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids
R Adili, M Hawley, M Holinstat
Prostaglandins & other lipid mediators 139, 10-18, 2018
1022018
MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression
R Teruel-Montoya, X Kong, S Abraham, L Ma, SP Kunapuli, M Holinstat, ...
PloS one 9 (7), e102259, 2014
1012014
Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation1 [S]
KN Ikei, J Yeung, PL Apopa, J Ceja, J Vesci, TR Holman, M Holinstat
Journal of lipid research 53 (12), 2546-2559, 2012
1012012
Interaural level difference processing in the lateral superior olive and the inferior colliculus
TJ Park, A Klug, M Holinstat, B Grothe
Journal of Neurophysiology 92 (1), 289-301, 2004
1012004
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