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Jitin Singla
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Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer
S Srihari, J Singla, L Wong, MA Ragan
Biology Direct 10, 2015
742015
Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell
J Singla, KM McClary, KL White, F Alber, A Sali, RC Stevens
Cell 173 (1), 11-19, 2018
672018
De Novo Structural Pattern Mining in Cellular Electron Cryotomograms
M Xu, J Singla, EI Tocheva, YW Chang, RC Stevens, GJ Jensen, F Alber
Structure, 2019
57*2019
Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach
S Srihari, M Kalimutho, S Lal, J Singla, D Patel, PT Simpson, KK Khanna, ...
Molecular BioSystems 12 (3), 963-972, 2016
422016
Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography
KL White, J Singla, V Loconte, JH Chen, A Ekman, L Sun, X Zhang, ...
Science Advances 6 (50), eabc8262, 2020
402020
Soft X-ray tomography to map and quantify organelle interactions at the mesoscale
V Loconte, J Singla, A Li, JH Chen, A Ekman, G McDermott, A Sali, ...
Structure 30 (4), 510-521. e3, 2022
282022
Bayesian metamodeling of complex biological systems across varying representations
B Raveh, L Sun, KL White, T Sanyal, J Tempkin, D Zheng, K Bharath, ...
Proceedings of the National Academy of Sciences 118 (35), e2104559118, 2021
272021
Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography
X Zhang, SD Carter, J Singla, KL White, PC Butler, RC Stevens, ...
Science Advances 6 (50), eabc8258, 2020
262020
Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion
A Li, X Zhang, J Singla, K White, V Loconte, C Hu, C Zhang, S Li, W Li, ...
PLOS ONE 17 (3), e0265567, 2022
102022
A community approach to whole-cell modeling
J Singla, KL White
Current Opinion in Systems Biology 26, 33-38, 2021
92021
A new visual design language for biological structures in a cell
J Singla, K Burdsall, B Cantrell, JR Halsey, A McDowell, C McGregor, ...
Structure 30, 1-13, 2022
32022
An Intensity-based Post-processing Tool for 3D Instance Segmentation of Organelles in Soft X-ray Tomograms
A Li, S Zhang, V Loconte, Y Liu, A Ekman, GJ Thompson, A Sali, ...
32022
Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography
J Singla, KL White, RC Stevens, F Alber
Journal of Structural Biology 213 (2), 2021
32021
Characterization of haloacid dehalogenase superfamily acid phosphatase from Staphylococcus lugdunensis
H Kaur, S Rode, KP Sandra, JK Mahto, MS Alam, DN Gupta, B Kar, ...
Archives of Biochemistry and Biophysics 753, 109888, 2024
22024
Database Evolution, by Scientists, for Scientists: A Case Study
RE Schuler, J Singla, B Vallat, KL White, HM Berman, C Kesselman
2023 IEEE 19th International Conference on e-Science (e-Science), 1-10, 2023
22023
Structure-guided mutations in CDRs for enhancing the affinity of neutralizing SARS-CoV-2 nanobody
V Singh, M Bhutkar, S Choudhary, S Nehul, R Kumar, J Singla, P Kumar, ...
Biochemical and Biophysical Research Communications 734, 150746, 2024
12024
Revealing the Native Molecular Architecture of the Nuclear Periphery using Cryo-Focused-Ion-Beam Milling, Light Microscopy and Electron Tomography
E Villa, R Watanabe, R Buschauer, K Khanna, V Lam, J Singla, F Alber
Microscopy and Microanalysis 23 (S1), 1248-1249, 2017
12017
Mechanistic and structural insights into EstS1 esterase: A potent broad-spectrum phthalate diester degrading enzyme
S Verma, S Choudhary, KA Kumar, JK Mahto, I Mishra, VB Prakash, ...
Structure, 2024
2024
In-silico characterization of a hypothetical protein of Sulfobacillus sp. hq2 for degradation of phthalate diesters
S Verma, A Singh, P Kumar, J Singla
International Journal of Biological Macromolecules 280, 136006, 2024
2024
Bioinformatics Databases and Tools Available for the Development of Antiviral Drugs
A Singh, P Dhaka, P Kumar, S Tomar, J Singla
Advances in Antiviral Research, 41-71, 2024
2024
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Articles 1–20