| Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence JE Savage, PR Jansen, S Stringer, K Watanabe, J Bryois, CA De Leeuw, ... Nature genetics 50 (7), 912-919, 2018 | 1075 | 2018 |
| Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function G Davies, M Lam, SE Harris, JW Trampush, M Luciano, WD Hill, ... Nature communications 9 (1), 2098, 2018 | 604 | 2018 |
| Effect of allelic variation at the NACP–Rep1 repeat upstream of the α-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system O Chiba-Falek, RL Nussbaum Human molecular genetics 10 (26), 3101-3109, 2001 | 286 | 2001 |
| GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium JW Trampush, MLZ Yang, J Yu, E Knowles, G Davies, DC Liewald, ... Molecular psychiatry 22 (3), 336-345, 2017 | 284 | 2017 |
| A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing G Davies, SE Harris, CA Reynolds, A Payton, HM Knight, DC Liewald, ... Molecular psychiatry 19 (1), 76-87, 2014 | 194 | 2014 |
| A comparison of the Cambridge Automated Neuropsychological Test Battery (CANTAB) with “traditional” neuropsychological testing instruments PJ Smith, AC Need, ET Cirulli, O Chiba-Falek, DK Attix Journal of clinical and experimental neuropsychology 35 (3), 319-328, 2013 | 193 | 2013 |
| Levels of alpha‐synuclein mRNA in sporadic Parkinson disease patients O Chiba‐Falek, GJ Lopez, RL Nussbaum Movement Disorders 21 (10), 1703-1708, 2006 | 192 | 2006 |
| Downregulation of SNCA expression by targeted editing of DNA methylation: a potential strategy for precision therapy in PD B Kantor, L Tagliafierro, J Gu, ME Zamora, E Ilich, C Grenier, ZY Huang, ... Molecular therapy 26 (11), 2638-2649, 2018 | 158 | 2018 |
| Genome-wide scan of copy number variation in late-onset Alzheimer's disease EL Heinzen, AC Need, KM Hayden, O Chiba-Falek, AD Roses, ... Journal of Alzheimer's Disease 19 (1), 69-77, 2010 | 151 | 2010 |
| Human and mouse α-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element JW Touchman, A Dehejia, O Chiba-Falek, DE Cabin, JR Schwartz, ... Genome research 11 (1), 78-86, 2001 | 151 | 2001 |
| Expansion of the Parkinson disease-associated SNCA- Rep1 allele upregulates human α-synuclein in transgenic mouse brain KD Cronin, D Ge, P Manninger, C Linnertz, A Rossoshek, BM Orrison, ... Human molecular genetics 18 (17), 3274-3285, 2009 | 134 | 2009 |
| Large-scale cognitive GWAS meta-analysis reveals tissue-specific neural expression and potential nootropic drug targets M Lam, JW Trampush, J Yu, E Knowles, G Davies, DC Liewald, JM Starr, ... Cell reports 21 (9), 2597-2613, 2017 | 124 | 2017 |
| Functional analysis of intra-allelic variation at NACP-Rep1 in the α-synuclein gene O Chiba-Falek, JW Touchman, RL Nussbaum Human genetics 113, 426-431, 2003 | 117 | 2003 |
| The molecular basis of disease variability among cystic fibrosis patients carrying the 3849+ 10 kb C→ T mutation O Chiba-Falek, E Kerem, T Shoshani, M Aviram, A Augarten, L Bentur, ... Genomics 53 (3), 276-283, 1998 | 117 | 1998 |
| Regulation of α-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene O Chiba-Falek, JA Kowalak, ME Smulson, RL Nussbaum The American Journal of Human Genetics 76 (3), 478-492, 2005 | 109 | 2005 |
| Pleiotropic meta-analysis of cognition, education, and schizophrenia differentiates roles of early neurodevelopmental and adult synaptic pathways M Lam, WD Hill, JW Trampush, J Yu, E Knowles, G Davies, E Stahl, ... The American Journal of Human Genetics 105 (2), 334-350, 2019 | 104 | 2019 |
| Genetic regulation of α-synuclein mRNA expression in various human brain tissues C Linnertz, L Saucier, D Ge, KD Cronin, JR Burke, JN Browndyke, ... PloS one 4 (10), e7480, 2009 | 102 | 2009 |
| Cystic fibrosis in Jews: frequency and mutation distribution B Kerem, O Chiba-Falek, E Kerem Genetic testing 1 (1), 35-39, 1997 | 93 | 1997 |
| The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes C Linnertz, L Anderson, W Gottschalk, D Crenshaw, MW Lutz, J Allen, ... Alzheimer's & Dementia 10 (5), 541-551, 2014 | 92 | 2014 |
| Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation M Nissim‐Rafinia, M Aviram, SH Randell, L Shushi, E Ozeri, ... EMBO reports 5 (11), 1071-1077, 2004 | 90 | 2004 |
