Robert Kleemann
Robert Kleemann
TNO, Dept. Metabolic Health Research, Leiden, The Netherlands
Geverifieerd e-mailadres voor tno.nl - Homepage
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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
J Bernhagen, R Krohn, H Lue, JL Gregory, A Zernecke, RR Koenen, ...
Nature medicine 13 (5), 587-596, 2007
10702007
Cytokines and atherosclerosis: a comprehensive review of studies in mice
R Kleemann, S Zadelaar, T Kooistra
Cardiovascular research 79 (3), 360-376, 2008
8072008
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
R Kleemann, A Hausser, G Geiger, R Mischke, A Burger-Kentischer, ...
Nature 408 (6809), 211-216, 2000
6422000
Mouse models for atherosclerosis and pharmaceutical modifiers
S Zadelaar, R Kleemann, L Verschuren, J de Vries-Van der Weij, ...
Arteriosclerosis, thrombosis, and vascular biology 27 (8), 1706-1721, 2007
5742007
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
H Lue, R Kleemann, T Calandra, T Roger, J Bernhagen
Microbes and infection 4 (4), 449-460, 2002
4372002
Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis
A Burger-Kentischer, H Goebel, R Seiler, G Fraedrich, HE Schaefer, ...
Circulation 105 (13), 1561-1566, 2002
3182002
Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase
R Kleemann, A Kapurniotu, RW Frank, A Gessner, R Mischke, O Flieger, ...
Journal of molecular biology 280 (1), 85-102, 1998
3031998
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that isá…
S Mandard, F Zandbergen, NS Tan, P Escher, D Patsouris, W Koenig, ...
Journal of Biological Chemistry 279 (33), 34411-34420, 2004
2922004
Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models
R Kleemann, L Verschuren, M Morrison, S Zadelaar, MJ van Erk, ...
Atherosclerosis 218 (1), 44-52, 2011
2772011
Fibrates down-regulate IL-1–stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB–C/EBP-β complex formation
R Kleemann, PP Gervois, L Verschuren, B Staels, HMG Princen, ...
Blood, The Journal of the American Society of Hematology 101 (2), 545-551, 2003
2402003
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis
R Kleemann, L Verschuren, MJ van Erk, Y Nikolsky, NHP Cnubben, ...
Genome biology 8 (9), R200, 2007
2362007
CLINICAL PERSPECTIVE
JHN Lindeman, H Abdul-Hussien, JH van Bockel, R Wolterbeek, ...
Circulation 119 (16), 2209-2216, 2009
2282009
Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-α activator fenofibrate
P Gervois, R Kleemann, A Pilon, F Percevault, W Koenig, B Staels, ...
Journal of Biological Chemistry 279 (16), 16154-16160, 2004
2212004
Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro
R Kleemann, L Verschuren, BJ de Rooij, J Lindeman, MM de Maat, ...
Blood 103 (11), 4188-4194, 2004
2192004
Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol–lowering effect in APOE* 3-Leiden transgenic mice: evidence forá…
R Kleemann, HMG Princen, JJ Emeis, JW Jukema, RD Fontijn, ...
Circulation 108 (11), 1368-1374, 2003
2162003
Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases
H Abdul-Hussien, RGV Soekhoe, E Weber, H Jan, R Kleemann, A Mulder, ...
The American journal of pathology 170 (3), 809-817, 2007
1962007
Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology
W Liang, AL Menke, A Driessen, GH Koek, JH Lindeman, R Stoop, ...
PloS one 9 (12), e115922, 2014
1812014
Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro
K Bellmann, A Wenz, J Radons, V Burkart, R Kleemann, H Kolb
J Clin Invest 95, 2840-2845, 1995
1811995
Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor α agonists via inhibition of CCAAT box/enhancer-binding protein β
P Gervois, N Vu-Dac, R Kleemann, M Kockx, G Dubois, B Laine, V Kosykh, ...
Journal of Biological Chemistry 276 (36), 33471-33477, 2001
1772001
Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats
R Kleemann, H Rothe, V Kolb-Bachofen, Q Xie, C Nathan, S Martin, ...
FEBS letters 328 (1-2), 9-12, 1993
1661993
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Artikelen 1–20