SCENIC: single-cell regulatory network inference and clustering S Aibar, CB González-Blas, T Moerman, VA Huynh-Thu, H Imrichova, ... Nature methods 14 (11), 1083-1086, 2017 | 4000 | 2017 |
iRegulon: from a gene list to a gene regulatory network using large motif and track collections R Janky, A Verfaillie, H Imrichová, B Van de Sande, L Standaert, ... PLoS computational biology 10 (7), e1003731, 2014 | 843 | 2014 |
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state A Verfaillie, H Imrichova, ZK Atak, M Dewaele, F Rambow, G Hulselmans, ... Nature communications 6 (1), 6683, 2015 | 437 | 2015 |
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion YR Yu, H Imrichova, H Wang, T Chao, Z Xiao, M Gao, M Rincon-Restrepo, ... Nature immunology 21 (12), 1540-1551, 2020 | 378 | 2020 |
Rational discovery of molecular glue degraders via scalable chemical profiling C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ... Nature chemical biology 16 (11), 1199-1207, 2020 | 260 | 2020 |
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells P Laurette, T Strub, D Koludrovic, C Keime, S Le Gras, H Seberg, ... Elife 4, e06857, 2015 | 197 | 2015 |
i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly H Imrichová, G Hulselmans, Z Kalender Atak, D Potier, S Aerts Nucleic acids research 43 (W1), W57-W64, 2015 | 185 | 2015 |
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes J Jacobs, M Atkins, K Davie, H Imrichova, L Romanelli, V Christiaens, ... Nature genetics 50 (7), 1011-1020, 2018 | 151 | 2018 |
Acute BAF perturbation causes immediate changes in chromatin accessibility S Schick, S Grosche, KE Kohl, D Drpic, MG Jaeger, NC Marella, ... Nature genetics 53 (3), 269-278, 2021 | 140 | 2021 |
Selective Mediator dependence of cell-type-specifying transcription MG Jaeger, B Schwalb, SD Mackowiak, T Velychko, A Hanzl, H Imrichova, ... Nature genetics 52 (7), 719-727, 2020 | 107 | 2020 |
Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry P Bouchal, OT Schubert, J Faktor, L Capkova, H Imrichova, K Zoufalova, ... Cell reports 28 (3), 832-843. e7, 2019 | 94 | 2019 |
Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic A Verfaillie, D Svetlichnyy, H Imrichova, K Davie, M Fiers, ZK Atak, ... Genome research 26 (7), 882-895, 2016 | 88 | 2016 |
Combined proteomics and transcriptomics identifies carboxypeptidase B1 and nuclear factor κB (NF-κB) associated proteins as putative biomarkers of metastasis in low grade … P Bouchal, M Dvořáková, T Roumeliotis, Z Bortlíček, I Ihnatová, ... Molecular & Cellular Proteomics 14 (7), 1814-1830, 2015 | 69 | 2015 |
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders A Hanzl, R Casement, H Imrichova, SJ Hughes, E Barone, A Testa, ... Nature chemical biology 19 (3), 323-333, 2023 | 67 | 2023 |
Targeted protein degradation via intramolecular bivalent glues O Hsia, M Hinterndorfer, AD Cowan, K Iso, T Ishida, R Sundaramoorthy, ... Nature 627 (8002), 204-211, 2024 | 54 | 2024 |
Immunoediting instructs tumor metabolic reprogramming to support immune evasion CH Tsai, YM Chuang, X Li, YR Yu, SF Tzeng, ST Teoh, KE Lindblad, ... Cell metabolism 35 (1), 118-133. e7, 2023 | 44 | 2023 |
iRegulon and i‐cisTarget: reconstructing regulatory networks using motif and track enrichment A Verfaillie, H Imrichova, R Janky, S Aerts Current protocols in bioinformatics 52 (1), 2.16. 1-2.16. 39, 2015 | 43 | 2015 |
Discovery of a drug-like, natural product-inspired Dcaf11 ligand Chemotype G Xue, J Xie, M Hinterndorfer, M Cigler, L Dötsch, H Imrichova, P Lampe, ... Nature Communications 14 (1), 7908, 2023 | 28 | 2023 |
Identification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest Models D Svetlichnyy, H Imrichova, M Fiers, Z Kalender Atak, S Aerts PLoS computational biology 11 (11), e1004590, 2015 | 28 | 2015 |
Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks Z Kalender Atak, H Imrichova, D Svetlichnyy, G Hulselmans, V Christiaens, ... Genome Medicine 9, 1-13, 2017 | 16 | 2017 |