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Alexander Koch
Alexander Koch
Senior Bioinformatics Scientist @ BioLizard
Geverifieerd e-mailadres voor alexanderkoch.be - Homepage
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Analysis of DNA methylation in cancer: location revisited
A Koch, SC Joosten, Z Feng, TC de Ruijter, MX Draht, V Melotte, ...
Nature Reviews Clinical Oncology 15 (7), 459-466, 2018
5432018
Alterations of immune response of non-small cell lung cancer with azacytidine
J Wrangle, W Wang, A Koch, H Easwaran, HP Mohammad, F Vendetti, ...
Oncotarget 4 (11), 2067, 2013
4052013
MEXPRESS: visualizing expression, DNA methylation and clinical TCGA data
A Koch, T De Meyer, J Jeschke, W Van Criekinge
BMC genomics 16 (1), 1-6, 2015
3102015
Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near …
G Menschaert, W Van Criekinge, T Notelaers, A Koch, J Crappé, ...
Molecular & cellular proteomics 12 (7), 1780-1790, 2013
2002013
MEXPRESS update 2019
A Koch, J Jeschke, W Van Criekinge, M van Engeland, T De Meyer
Nucleic acids research 47 (W1), W561-W565, 2019
1882019
PROTEOFORMER: deep proteome coverage through ribosome profiling and MS integration
J Crappé, E Ndah, A Koch, S Steyaert, D Gawron, S De Keulenaer, ...
Nucleic acids research 43 (5), e29-e29, 2015
1602015
Epigenetics in renal cell cancer: mechanisms and clinical applications
SC Joosten, KM Smits, MJ Aarts, V Melotte, A Koch, VC Tjan-Heijnen, ...
Nature Reviews Urology 15 (7), 430-451, 2018
1452018
DNA methylation–based immune response signature improves patient diagnosis in multiple cancers
J Jeschke, M Bizet, C Desmedt, E Calonne, S Dedeurwaerder, S Garaud, ...
The Journal of clinical investigation 127 (8), 3090-3102, 2017
1252017
A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation …
A Koch, D Gawron, S Steyaert, E Ndah, J Crappé, S De Keulenaer, ...
Proteomics 14 (23-24), 2688-2698, 2014
812014
Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen
J Jeschke, L Van Neste, SC Glöckner, M Dhir, MF Calmon, V Deregowski, ...
Epigenetics 7 (7), 701-709, 2012
752012
Nervous NDRGs: the N-myc downstream–regulated gene family in the central and peripheral nervous system
SL Schonkeren, M Massen, R van der Horst, A Koch, N Vaes, V Melotte
neurogenetics 20 (4), 173-186, 2019
452019
Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review
MXG Draht, D Goudkade, A Koch, HI Grabsch, MP Weijenberg, ...
Clinical epigenetics 10 (1), 1-16, 2018
402018
The role of enteric neurons in the development and progression of colorectal cancer
G Rademakers, N Vaes, S Schonkeren, A Koch, KA Sharkey, V Melotte
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (2), 420-434, 2017
402017
Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors
J Jeschke, E Collignon, C Al Wardi, M Krayem, M Bizet, Y Jia, S Garaud, ...
Nature Cancer 2 (6), 611-628, 2021
372021
Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients
T Seremet, A Koch, Y Jansen, M Schreuer, S Wilgenhof, V Del Marmol, ...
Journal of translational medicine 14 (1), 1-14, 2016
322016
Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC
G Rademakers, M Massen, A Koch, MX Draht, N Buekers, KAD Wouters, ...
Clinical Epigenetics 13 (1), 1-12, 2021
272021
Development of a prognostic risk model for clear cell renal cell carcinoma by systematic evaluation of DNA methylation markers
SC Joosten, SNO Odeh, A Koch, N Buekers, MJB Aarts, M Baldewijns, ...
Clinical Epigenetics 13 (1), 1-11, 2021
162021
Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2
N Vaes, SL Schonkeren, G Rademakers, AM Holland, A Koch, MJ Gijbels, ...
EMBO reports 22 (6), e51913, 2021
152021
A combined literature and in silico analysis enlightens the role of the NDRG family in the gut
N Vaes, SL Schonkeren, E Brosens, A Koch, CJ McCann, N Thapar, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (10), 2140-2151, 2018
152018
ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer
TG Keulers, A Koch, MW van Gisbergen, LMO Barbeau, MI Zonneveld, ...
Autophagy, 1-17, 2022
122022
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Artikelen 1–20