Joanna Holbrook
Joanna Holbrook
SVP Research
Geverifieerd e-mailadres voor cegx.co.uk - Homepage
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Resistin is expressed in human macrophages and directly regulated by PPARγ activators
L Patel, AC Buckels, IJ Kinghorn, PR Murdock, JD Holbrook, C Plumpton, ...
Biochemical and biophysical research communications 300 (2), 472-476, 2003
11672003
Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study
SE Soh, MT Tint, PD Gluckman, KM Godfrey, A Rifkin-Graboi, YH Chan, ...
International journal of epidemiology 43 (5), 1401-1409, 2014
2802014
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
AL Teh, H Pan, L Chen, ML Ong, S Dogra, J Wong, JL MacIsaac, SM Mah, ...
Genome research 24 (7), 1064-1074, 2014
2672014
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
N Kato, M Loh, F Takeuchi, N Verweij, X Wang, W Zhang, TN Kelly, ...
Nature genetics 47 (11), 1282-1293, 2015
2392015
Dynamics of infant gut microbiota are influenced by delivery mode and gestational duration and are associated with subsequent adiposity
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
MBio 6 (1), 2015
2012015
Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family
G Brooke, JD Holbrook, MH Brown, AN Barclay
The Journal of Immunology 173 (4), 2562-2570, 2004
1282004
Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212
J Jing, J Greshock, JD Holbrook, A Gilmartin, X Zhang, E McNeil, ...
Molecular cancer therapeutics 11 (3), 720-729, 2012
1212012
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine
JD Holbrook, JS Parker, KT Gallagher, WS Halsey, AM Hughes, ...
Journal of translational medicine 9 (1), 1-13, 2011
902011
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome
X Lin, IY Lim, Y Wu, AL Teh, L Chen, IM Aris, SE Soh, MT Tint, ...
BMC medicine 15 (1), 1-18, 2017
882017
The translational value of rodent gastrointestinal functions: a cautionary tale
GJ Sanger, JD Holbrook, PLR Andrews
Trends in pharmacological sciences 32 (7), 402-409, 2011
882011
Characterisation of 5‐HT3C, 5‐HT3D and 5‐HT3E receptor subunits: evolution, distribution and function
JD Holbrook, CH Gill, N Zebda, JP Spencer, R Leyland, KH Rance, ...
Journal of neurochemistry 108 (2), 384-396, 2009
842009
Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and …
C Olsson, JD Holbrook, G Bompadre, E Jönsson, CHV Hoyle, GJ Sanger, ...
General and comparative endocrinology 155 (1), 217-226, 2008
812008
Novel region discovery method for Infinium 450K DNA methylation data reveals changes associated with aging in muscle and neuronal pathways
ML Ong, JD Holbrook
Aging cell 13 (1), 142-155, 2014
772014
The role of positive selection in determining the molecular cause of species differences in disease
JJ Vamathevan, S Hasan, RD Emes, H Amrine-Madsen, D Rajagopalan, ...
BMC Evolutionary Biology 8 (1), 1-14, 2008
752008
Global DNA hypermethylation in down syndrome placenta
S Jin, YK Lee, YC Lim, Z Zheng, XM Lin, DPY Ng, JD Holbrook, HY Law, ...
PLoS Genet 9 (6), e1003515, 2013
732013
Measuring the methylome in clinical samples: improved processing of the Infinium Human Methylation450 BeadChip Array
H Pan, L Chen, S Dogra, A Ling Teh, J Hao Tan, YI Lim, YC Lim, S Jin, ...
Epigenetics 7 (10), 1173-1187, 2012
732012
COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology
A Qiu, TA Tuan, ML Ong, Y Li, H Chen, A Rifkin-Graboi, BFP Broekman, ...
American Journal of Psychiatry 172 (2), 163-172, 2015
722015
Bioinformatics and type II G-protein-coupled receptors
SM Foord, S Jupe, J Holbrook
Biochemical Society Transactions 30 (4), 473-479, 2002
692002
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
RC Huang, ES Garratt, H Pan, Y Wu, EA Davis, SJ Barton, GC Burdge, ...
Epigenetics 10 (11), 995-1005, 2015
682015
Rate of establishing the gut microbiota in infancy has consequences for future health
S Dogra, O Sakwinska, SE Soh, C Ngom-Bru, WM Brück, B Berger, ...
Gut Microbes 6 (5), 321-325, 2015
672015
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Artikelen 1–20