Jacob Lund
Jacob Lund
Verified email at novonordisk.com
Title
Cited by
Cited by
Year
Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death
M Nyegaard, MT Overgaard, MT Søndergaard, M Vranas, ER Behr, ...
The American Journal of Human Genetics 91 (4), 703-712, 2012
3462012
ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity
J Lund, OH Olsen, ES Sørensen, HR Stennicke, HH Petersen, ...
Journal of Biological Chemistry 288 (29), 21367-21375, 2013
212013
Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex
J Lund, MT Søndergaard, CA Conover, MT Overgaard
J Mol Endocrinol 52 (3), 345-55, 2014
182014
Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors
J Lund, L Troeberg, H Kjeldal, OH Olsen, H Nagase, ES Sørensen, ...
Journal of Biological Chemistry 290 (10), 6620-6629, 2015
112015
Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo
SL Kjellev, H Østergaard, PJ Greisen, MB Hermit, K Thorn, BG Hansen, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
72019
Modulation of the activated protein C pathway in severe haemophilia A patients: The effects of thrombomodulin and a factor V‐stabilizing fab
DF Brophy, EJ Martin, BM Mohammed, JC Barrett, JG Kuhn, ME Nolte, ...
Haemophilia 23 (6), 941-947, 2017
42017
Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma
J Lund, AM Elimar Bitsch, M Grønbech Rasch, M Enoksson, L Troeberg, ...
MAbs 10 (1), 118-128, 2018
22018
A FVIIIa-mimetic bispecific antibody (Mim8) ameliorates bleeding upon severe vascular challenge in hemophilia A mice
H Østergaard, J Lund, S Kjellev, A Henriksen, N Lorenzen, E Johansson, ...
Blood, 2021
2021
Factor x binders enhancing fx activation
J Lund, K Thorn, MN Harndahl, MA Buyse, E De Tavernier, S Steffensen
US Patent App. 16/764,124, 2021
2021
Prolonging coagulant activity of factor Xa under hemophilic conditions by site-specific N-glycosylation of the surface-exposed autolysis loop
AC Bonde, J Lund, JJ Hansen, JR Winther, S Zahn, P Tiainen, OH Olsen, ...
bioRxiv, 2021
2021
Mette Nyegaard,* Michael T. Overgaard, 2, 8 Mads T. Søndergaard, 2 Marta Vranas, Elijah R. Behr, 3
LL Hildebrandt, J Lund, PL Hedley, AJ Camm, G Wettrell, I Fosdal, ...
The American Journal of Human Genetics 91, 703-712, 2012
2012
Development of Real Time Proteolytic Assays using Fluorescent Protein Substrates
SH Jensen, J Lund, MT Overgaard
2011
Heparin binding properties of the IGF-II/IGFBP-2 complex
J Lund, MT Søndergaard, SH Jensen, F Aasted, EK Andresen, ...
2010
OR6, 35 Heparin binding properties of the IGF-II/IGFBP-2 complex
J Lund, MT Søndergaard, SH Jensen, F Aasted, EK Andresen, ...
Growth Hormone & IGF Research, S15-S16, 2010
2010
A Novel Anabolic Therapy for Osteoporosis
J Lund, MB Brøndum, MT Søndergaard, MT Overgaard
2009
Two-Dimensional Shape Sensitivity Analysis: A Fixed Basis Function Finite Element Approach
JS Hansen, J Lund
Two-Dimensional Shape Sensitivity Analysis, 2000
2000
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Articles 1–16