Tom Kilduff
Tom Kilduff
Center Director, Center for Neuroscience, SRI International
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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
L De Lecea, TS Kilduff, C Peyron, XB Gao, PE Foye, PE Danielson, ...
Proceedings of the National Academy of Sciences 95 (1), 322-327, 1998
Neurons containing hypocretin (orexin) project to multiple neuronal systems
C Peyron, DK Tighe, AN Van Den Pol, L De Lecea, HC Heller, JG Sutcliffe, ...
Journal of Neuroscience 18 (23), 9996-10015, 1998
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
TL Horvath, C Peyron, S Diano, A Ivanov, G Aston‐Jones, TS Kilduff, ...
Journal of Comparative Neurology 415 (2), 145-159, 1999
Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin
AN Van Den Pol, XB Gao, K Obrietan, TS Kilduff, AB Belousov
Journal of Neuroscience 18 (19), 7962-7971, 1998
The hypocretin/orexin ligand–receptor system: implications for sleep and sleep disorders
TS Kilduff, C Peyron
Trends in neurosciences 23 (8), 359-365, 2000
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response
R Winsky-Sommerer, A Yamanaka, S Diano, E Borok, AJ Roberts, ...
Journal of Neuroscience 24 (50), 11439-11448, 2004
Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat
D Gerashchenko, MD Kohls, MA Greco, NS Waleh, R Salin-Pascual, ...
Journal of Neuroscience 21 (18), 7273-7283, 2001
A role for cryptochromes in sleep regulation
JP Wisor, BF O'Hara, A Terao, CP Selby, TS Kilduff, A Sancar, DM Edgar, ...
Bmc Neuroscience 3 (1), 1-14, 2002
Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice
T Tsunematsu, TS Kilduff, ES Boyden, S Takahashi, M Tominaga, ...
Journal of Neuroscience 31 (29), 10529-10539, 2011
Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor
Y Muraki, A Yamanaka, N Tsujino, TS Kilduff, K Goto, T Sakurai
Journal of Neuroscience 24 (32), 7159-7166, 2004
Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation
T Tsunematsu, T Ueno, S Tabuchi, A Inutsuka, KF Tanaka, H Hasuwa, ...
Journal of Neuroscience 34 (20), 6896-6909, 2014
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic-and antidepressant-like activity, improve cognition and control body weight
FG Revel, JL Moreau, B Pouzet, R Mory, A Bradaia, D Buchy, V Metzler, ...
Molecular psychiatry 18 (5), 543-556, 2013
Identification of a population of sleep-active cerebral cortex neurons
D Gerashchenko, JP Wisor, D Burns, RK Reh, PJ Shiromani, T Sakurai, ...
Proceedings of the National Academy of Sciences 105 (29), 10227-10232, 2008
Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function
S Tabuchi, T Tsunematsu, SW Black, M Tominaga, M Maruyama, ...
Journal of Neuroscience 34 (19), 6495-6509, 2014
Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep
A Terao, TL Steininger, K Hyder, A Apte-Deshpande, J Ding, ...
Neuroscience 116 (1), 187-200, 2003
The neurobiology of sleep and wakefulness
MD Schwartz, TS Kilduff
Psychiatric Clinics 38 (4), 615-644, 2015
Circadian and light-induced expression of immediate early gene mRNAs in the rat suprachiasmatic nucleus
EL Sutin, TS Kilduff
Molecular brain research 15 (3-4), 281-290, 1992
Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor
N Tsujino, A Yamanaka, K Ichiki, Y Muraki, TS Kilduff, K Yagami, ...
Journal of Neuroscience 25 (32), 7459-7469, 2005
Immune response gene expression increases in the aging murine hippocampus
A Terao, A Apte-Deshpande, L Dousman, S Morairty, BP Eynon, ...
Journal of neuroimmunology 132 (1-2), 99-112, 2002
Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner
A Yamanaka, Y Muraki, K Ichiki, N Tsujino, TS Kilduff, K Goto, T Sakurai
Journal of neurophysiology 96 (1), 284-298, 2006
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