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Buvana Ravishankar
Buvana Ravishankar
FLX BIO, Inc.
Geverifieerd e-mailadres voor flxbio.com
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Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen
TL McGaha, Y Chen, B Ravishankar, N Van Rooijen, MCI Karlsson
Blood, The Journal of the American Society of Hematology 117 (20), 5403-5412, 2011
2282011
Tolerance to apoptotic cells is regulated by indoleamine 2, 3-dioxygenase
B Ravishankar, H Liu, R Shinde, P Chandler, B Baban, M Tanaka, ...
Proceedings of the National Academy of Sciences 109 (10), 3909-3914, 2012
2082012
The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity
B Ravishankar, H Liu, R Shinde, K Chaudhary, W Xiao, J Bradley, ...
Proceedings of the National Academy of Sciences 112 (34), 10774-10779, 2015
1512015
Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans
R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ...
Nature immunology 19 (6), 571-582, 2018
1452018
Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses
L Huang, L Li, H Lemos, PR Chandler, G Pacholczyk, B Baban, ...
The Journal of Immunology 191 (7), 3509-3513, 2013
1292013
Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance
B Ravishankar, R Shinde, H Liu, K Chaudhary, J Bradley, HP Lemos, ...
Proceedings of the National Academy of Sciences 111 (11), 4215-4220, 2014
1142014
NRF2 activation promotes aggressive lung cancer and associates with poor clinical outcomes
A Singh, A Daemen, D Nickles, SM Jeon, O Foreman, K Sudini, F Gnad, ...
Clinical Cancer Research 27 (3), 877-888, 2021
962021
Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells
L Huang, HP Lemos, L Li, MH Li, PR Chandler, B Baban, TL McGaha, ...
The Journal of Immunology 188 (10), 4913-4920, 2012
762012
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors
TJ Hagenbeek, JD Webster, NM Kljavin, MT Chang, T Pham, HJ Lee, ...
Science signaling 11 (547), eaaj1757, 2018
752018
Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy
K Chaudhary, R Shinde, H Liu, JP Gnana-Prakasam, ...
The Journal of Immunology 194 (12), 5713-5724, 2015
442015
O death where is thy sting? Immunologic tolerance to apoptotic self
B Ravishankar, TL McGaha
Cellular and molecular life sciences 70, 3571-3589, 2013
192013
Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy
JJ Jackson, GM Shibuya, B Ravishankar, L Adusumilli, D Bradford, ...
Journal of Medicinal Chemistry 65 (19), 12895-12924, 2022
42022
Heterologous protein incites abnormal plasma cell accumulation and autoimmunity in MRL-MpJ mice
TL McGaha, Z Ma, B Ravishankar, K Gabunia, M Mcmenamin, MP Madaio
Autoimmunity 45 (4), 279-289, 2012
42012
Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment
B Ravishankar, L Adusumilli, DP Pookot, E Hunag, R Sreenivasan, ...
Proceedings of the American Association for Cancer Research Annual Meeting …, 2019
12019
Early events in immunologic tolerance to apoptotic cells are dependent on marginal zone macrophage CCL22 production.(P4081)
B Ravishankar, P Chandler, T McGaha
The Journal of Immunology 190 (1_Supplement), 127.12-127.12, 2013
12013
Innate and adaptive tolerance to apoptotic cells is controlled by an IDO-dependent mechanism.(123.49)
B Ravishankar, H Liu, R Shinde, P Chandler, T McGaha
The Journal of Immunology 188 (1_Supplement), 123.49-123.49, 2012
12012
Targeting the stress response kinase GCN2 to restore immunity in the tumor microenvironment
L Marshall, B Ravishankar, L Adusumilli, M Zibinsky, D Pookot, E Huang, ...
Cancer Research 81 (13), 2021
2021
Apoptotic cell driven ROS burst drives AhR dependent immunologic tolerance and suppression of lupus
RS Shinde, K Hezaveh, L Utsch, S Lamorte, B Ravishankar, H Liu, ...
The Journal of Immunology 198 (1_Supplement), 224.15-224.15, 2017
2017
The role of GCN2 in type-2 mucosal inflammation within the lung (IRM7P. 483)
J Bradley, H Liu, B Ravishankar, L Huang, A Perdue, J Urban, T McGaha
The Journal of Immunology 192 (1_Supplement), 126.8-126.8, 2014
2014
Role of splenic macrophages in the initiation of tolerance to apoptotic cell associated antigens
B Ravishankar
Georgia Regents University, 2014
2014
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Artikelen 1–20