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Simon Van Herck
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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
B Hassannia, B Wiernicki, I Ingold, F Qu, S Van Herck, YY Tyurina, ...
The Journal of clinical investigation 128 (8), 3341-3355, 2018
4752018
Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models
F Fenaroli, U Repnik, Y Xu, K Johann, S Van Herck, P Dey, FM Skjeldal, ...
ACS nano 12 (8), 8646-8661, 2018
972018
Delivery of STING agonists for adjuvanting subunit vaccines
S Van Herck, B Feng, L Tang
Advanced drug delivery reviews 179, 114020, 2021
782021
Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles
B Wang, S Van Herck, Y Chen, X Bai, Z Zhong, K Deswarte, ...
Journal of the American Chemical Society 142 (28), 12133-12139, 2020
592020
Zebrafish embryos allow prediction of nanoparticle circulation times in mice and facilitate quantification of nanoparticle–cell interactions
NJK Dal, A Kocere, J Wohlmann, S Van Herck, TA Bauer, J Resseguier, ...
Small 16 (5), 1906719, 2020
532020
Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine
S Jangra, J De Vrieze, A Choi, R Rathnasinghe, G Laghlali, A Uvyn, ...
Angewandte Chemie International Edition 60 (17), 9467-9473, 2021
512021
Lymph-node-targeted immune activation by engineered block copolymer amphiphiles–TLR7/8 agonist conjugates
S Van Herck, K Deswarte, L Nuhn, Z Zhong, JP Portela Catani, Y Li, ...
Journal of the American Chemical Society 140 (43), 14300-14307, 2018
492018
FRET monitoring of intracellular ketal hydrolysis in synthetic nanoparticles
L Nuhn, S Van Herck, A Best, K Deswarte, M Kokkinopoulou, I Lieberwirth, ...
Angewandte Chemie International Edition 57 (33), 10760-10764, 2018
472018
Potent lymphatic translocation and spatial control over innate immune activation by polymer–lipid amphiphile conjugates of small‐molecule TLR7/8 agonists
J De Vrieze, B Louage, K Deswarte, Z Zhong, R De Coen, S Van Herck, ...
Angewandte Chemie International Edition 58 (43), 15390-15395, 2019
432019
A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window
Z Zhang, H Li, S Kasmi, S Van Herck, K Deswarte, BN Lambrecht, ...
Angewandte Chemie International Edition 58 (23), 7866-7872, 2019
432019
A manganese phosphate nanocluster activates the cGAS‐STING pathway for enhanced cancer immunotherapy
M Gao, YQ Xie, K Lei, Y Zhao, A Kurum, S Van Herck, Y Guo, X Hu, ...
Advanced Therapeutics 4 (8), 2100065, 2021
392021
pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated Ester scaffolds: Synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish
A Van Driessche, A Kocere, H Everaert, L Nuhn, S Van Herck, G Griffiths, ...
Chemistry of Materials 30 (23), 8587-8596, 2018
312018
Switchable immune modulator for tumor-specific activation of anticancer immunity
Y Zhao, YQ Xie, S Van Herck, S Nassiri, M Gao, Y Guo, L Tang
Science advances 7 (37), eabg7291, 2021
272021
Transiently thermoresponsive acetal polymers for safe and effective administration of amphotericin B as a vaccine adjuvant
S Van Herck, L Van Hoecke, B Louage, L Lybaert, R De Coen, S Kasmi, ...
Bioconjugate Chemistry 29 (3), 748-760, 2017
232017
Lipid-polyglutamate nanoparticle vaccine platform
D Van Lysebetten, A Malfanti, K Deswarte, K Koynov, B Golba, T Ye, ...
ACS applied materials & interfaces 13 (5), 6011-6022, 2021
222021
Downstream processing from hot-melt extrusion towards tablets: A quality by design approach
W Grymonpré, N Bostijn, S Van Herck, G Verstraete, V Vanhoorne, ...
International Journal of Pharmaceutics 531 (1), 235-245, 2017
212017
Nanomedicine-mediated alteration of the pharmacokinetic profile of small molecule cancer immunotherapeutics
S Van Herck, BG De Geest
Acta Pharmacologica Sinica 41 (7), 881-894, 2020
182020
A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution
FP Garcia, M Rippe, MVP Companhoni, TF Stefanello, B Louage, ...
Biomaterials science 6 (7), 1754-1763, 2018
182018
Uptake of long protein-polyelectrolyte nanotubes by dendritic cells
DG Ramírez-Wong, S Saghazadeh, S Van Herck, BG De Geest, ...
Biomacromolecules 18 (12), 4299-4306, 2017
162017
In Situ Tumor Vaccination with Calcium‐Linked Degradable Coacervate Nanocomplex Co‐Delivering Photosensitizer and TLR7/8 Agonist to Trigger Effective Anti‐Tumor Immune Responses
Y Liu, H Li, H Zhao, Y Hao, S Van Herck, Z Xu, G Wang, X Wang, X Zhang, ...
Advanced Healthcare Materials 11 (12), 2102781, 2022
132022
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