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Adam Hagymasi
Adam Hagymasi
Director of Human Immunotherapy Translational Core, UConn Health
Geverifieerd e-mailadres voor uchc.edu
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CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation
HZ Qui, AT Hagymasi, S Bandyopadhyay, MC St Rose, ...
The Journal of Immunology 187 (7), 3555-3564, 2011
1812011
Glycoprotein 96 can chaperone both MHC class I-and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function
ADH Doody, JT Kovalchin, MA Mihalyo, AT Hagymasi, CG Drake, ...
The Journal of immunology 172 (10), 6087-6092, 2004
1772004
Endocannabinoid system acts as a regulator of immune homeostasis in the gut
N Acharya, S Penukonda, T Shcheglova, AT Hagymasi, S Basu, ...
Proceedings of the National Academy of Sciences 114 (19), 5005-5010, 2017
1512017
A novel sphingomyelinase‐like enzyme in Ixodes scapularis tick saliva drives host CD4+ T cells to express IL‐4
FJ ALARCON‐CHAIDEZ, VD Boppana, AT Hagymasi, AJ Adler, SK Wikel
Parasite immunology 31 (4), 210-219, 2009
432009
CD134/CD137 dual costimulation‐elicited IFN‐γ maximizes effector T‐cell function but limits Treg expansion
MC St. Rose, RA Taylor, S Bandyopadhyay, HZ Qui, AT Hagymasi, ...
Immunology and cell biology 91 (2), 173-183, 2013
412013
Dendritic cells program non‐immunogenic prostate‐specific T cell responses beginning at early stages of prostate tumorigenesis
MA Mihalyo, AT Hagymasi, AM Slaiby, EE Nevius, AJ Adler
The Prostate 67 (5), 536-546, 2007
332007
Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation
S Bandyopadhyay, M Long, HZ Qui, AT Hagymasi, AM Slaiby, ...
The Journal of Immunology 181 (11), 7728-7737, 2008
302008
An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection
CA Brennick, MM George, MM Moussa, AT Hagymasi, S Al Seesi, ...
The Journal of clinical investigation 131 (3), 2021
282021
T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-γ expression
M Long, AM Slaiby, AT Hagymasi, MA Mihalyo, AC Lichtler, SL Reiner, ...
The Journal of Immunology 176 (2), 1036-1045, 2006
242006
Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells
AT Hagymasi, AM Slaiby, MA Mihalyo, HZ Qui, DJ Zammit, L Lefrancois, ...
The Journal of Immunology 179 (3), 1524-1531, 2007
232007
Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope
H Ebrahimi-Nik, M Moussa, RP Englander, S Singhaviranon, J Michaux, ...
Nature Communications 12 (1), 6423, 2021
202021
Heat‐Shock Proteins
AT Hagymasi, JP Dempsey, PK Srivastava
Current protocols 2 (11), e592, 2022
192022
Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-γ expression during subsequent immunization to the same antigen
M Long, AM Slaiby, S Wu, AT Hagymasi, MA Mihalyo, S Bandyopadhyay, ...
The Journal of Immunology 179 (9), 5669-5677, 2007
132007
An immunotherapeutic CD137 agonist releases eomesodermin from ThPOK repression in CD4 T cells
P Mittal, R Abblett, JM Ryan, AT Hagymasi, A Agyekum-Yamoah, ...
The Journal of Immunology 200 (4), 1513-1526, 2018
102018
The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cells
MC St Rose, HZ Qui, S Bandyopadhyay, MA Mihalyo, AT Hagymasi, ...
The Journal of Immunology 183 (8), 4975-4983, 2009
82009
GRK2 enforces androgen receptor dependence in the prostate and prostate tumors
AJ Adler, P Mittal, AT Hagymasi, A Menoret, C Shen, F Agliano, KT Wright, ...
Oncogene 39 (11), 2424-2436, 2020
42020
Low avidity CD8+ T cells are less exhausted than their high avidity counterparts and provide superior anti-tumor immunity
S Singhaviranon, J Dempsey, A Hagymasi, I Mandoiu, PK Srivastava
The Journal of Immunology 210 (1_Supplement), 171.10-171.10, 2023
12023
Geneo: a bioinformatics toolbox for genomics-guided neoepitope prediction
S Al Seesi, A Al-Okaily, TV Shcheglova, E Sherafat, FH Alqahtani, ...
Journal of Computational Biology 30 (4), 538-551, 2023
12023
Gp96 can chaperone both MHC class I and class II-restricted epitopes for in vivo presentation, but selectively primes CD8 (+) T-cell effector function
ADH Doody, JT Kovalchin, MA Mihalyo, AT Hagymasi, CG Drake, ...
Immunology 114 (1), 141-141, 2005
12005
Low avidity T cells drive endogenous tumor immunity in mice and humans
P Srivastava, S Singhaviranon, J Dempsey, A Hagymasi, I Mandoiu
2024
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Artikelen 1–20