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Václav Bazgier
Václav Bazgier
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Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures
D Sehnal, S Bittrich, M Deshpande, R Svobodová, K Berka, V Bazgier, ...
Nucleic acids research 49 (W1), W431-W437, 2021
6692021
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
L Pravda, D Sehnal, D Toušek, V Navrátilová, V Bazgier, K Berka, ...
Nucleic acids research 46 (W1), W368-W373, 2018
2402018
Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners
M Šrejber, V Navrátilová, M Paloncýová, V Bazgier, K Berka, ...
Journal of inorganic biochemistry 183, 117-136, 2018
1522018
Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study
PF Lamie, WAM Ali, V Bazgier, L Rárová
European journal of medicinal chemistry 123, 803-813, 2016
912016
A novel series of highly potent 2, 6, 9-trisubstituted purine cyclin-dependent kinase inhibitors
T Gucky, R Jorda, M Zatloukal, V Bazgier, K Berka, E Reznickova, T Béres, ...
Journal of medicinal chemistry 56 (15), 6234-6247, 2013
582013
Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase
J Nisler, D Kopečný, R Končitíková, M Zatloukal, V Bazgier, K Berka, ...
Plant Molecular Biology 92, 235-248, 2016
562016
Antiallergic effects of pigments isolated from green sea urchin (Strongylocentrotus droebachiensis) shells
ON Pozharitskaya, AN Shikov, MN Makarova, SA Ivanova, VM Kosman, ...
Planta medica, 1698-1704, 2013
512013
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors
CB Baltus, R Jorda, C Marot, K Berka, V Bazgier, V Kryštof, G Prié, ...
European journal of medicinal chemistry 108, 701-719, 2016
452016
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl-N6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute …
T Gucky, E Reznickova, T Radošová Muchová, R Jorda, Z Klejova, ...
Journal of Medicinal Chemistry 61 (9), 3855-3869, 2018
402018
Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor
A Carazo, L Hyrsova, J Dusek, H Chodounska, A Horvatova, K Berka, ...
Toxicology Letters 265, 86-96, 2017
372017
Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo [4, 3-e][1, 2, 4] triazines
M Mojzych, V Šubertová, A Bielawska, K Bielawski, V Bazgier, K Berka, ...
European Journal of Medicinal Chemistry 78, 217-224, 2014
372014
Design, synthesis and biological activities of new brassinosteroid analogues with a phenyl group in the side chain
M Kvasnica, J Oklestkova, V Bazgier, L Rárová, P Korinkova, J Mikulík, ...
Organic & Biomolecular Chemistry 14 (37), 8691-8701, 2016
242016
Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain
M Kvasnica, J Oklestkova, V Bazgier, L Rarova, K Berka, M Strnad
Steroids 85, 58-64, 2014
242014
Synthesis of novel galeterone derivatives and evaluation of their in vitro activity against prostate cancer cell lines
R Jorda, E Řezníčková, U Kiełczewska, J Maj, JW Morzycki, ...
European journal of medicinal chemistry 179, 483-492, 2019
222019
Characterization of a Pyrazolo[4,3‐d]pyrimidine Inhibitor of Cyclin‐Dependent Kinases 2 and 5 and Aurora A With Pro‐Apoptotic and Anti‐Angiogenic Activity In Vitro
E Řezníčková, S Weitensteiner, L Havlíček, R Jorda, T Gucký, K Berka, ...
Chemical Biology & Drug Design 86 (6), 1528-1540, 2015
192015
Novel thiazolidinedione-hydroxamates as inhibitors of Mycobacterium tuberculosis virulence factor Zmp1
V Šlachtová, M Šebela, E Torfs, L Oorts, D Cappoen, K Berka, V Bazgier, ...
European Journal of Medicinal Chemistry 185, 111812, 2020
172020
Synthesis of dihydrotestosterone derivatives modified in the A-ring with (hetero) arylidene, pyrazolo [1, 5-a] pyrimidine and triazolo [1, 5-a] pyrimidine moieties and their …
MA Kiss, M Peřina, V Bazgier, NV May, Á Baji, R Jorda, É Frank
The Journal of Steroid Biochemistry and Molecular Biology 211, 105904, 2021
152021
Synthesis of novel aryl brassinosteroids through alkene cross-metathesis and preliminary biological study
P Korinkova, V Bazgier, J Oklestkova, L Rarova, M Strnad, M Kvasnica
Steroids 127, 46-55, 2017
142017
2, 6, 9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro
E Řezníčková, A Popa, T Gucký, M Zatloukal, L Havlíček, V Bazgier, ...
Bioorganic & medicinal chemistry letters 25 (11), 2298-2301, 2015
142015
MolMeDB: molecules on membranes database
J Juračka, M Šrejber, M Melíková, V Bazgier, K Berka
Database 2019, baz078, 2019
132019
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