|Thymocyte apoptosis induced by p53-dependent and independent pathways|
AR Clarke, CA Purdie, DJ Harrison, RG Morris, CC Bird, ML Hooper, ...
Nature 362 (6423), 849-852, 1993
|The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.|
J Janson, RH Ashley, D Harrison, S McIntyre, PC Butler
Diabetes 48 (3), 491-498, 1999
|Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema|
CAD Smith, DJ Harrison
The Lancet 350 (9078), 630-633, 1997
|Orphan CpG islands identify numerous conserved promoters in the mammalian genome|
RS Illingworth, U Gruenewald-Schneider, S Webb, ARW Kerr, KD James, ...
PLoS genetics 6 (9), e1001134, 2010
|High-frequency developmental abnormalities in p53-deficient mice|
JF Armstrong, MH Kaufman, DJ Harrison, AR Clarke
Current Biology 5 (8), 931-936, 1995
|Cell death in health and disease: the biology and regulation of apoptosis|
COC Bellamy, RDG Malcolmson, DJ Harrison, AH Wyllie
Seminars in cancer biology 6 (1), 3-16, 1995
|Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene.|
CA Purdie, DJ Harrison, A Peter, L Dobbie, S White, SE Howie, DM Salter, ...
Oncogene 9 (2), 603-609, 1994
|Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes|
CE Nestor, R Ottaviano, J Reddington, D Sproul, D Reinhardt, D Dunican, ...
Genome research 22 (3), 467-477, 2012
|Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion|
PN Newsome, I Johannessen, S Boyle, E Dalakas, KA Mcaulay, ...
Gastroenterology 124 (7), 1891-1900, 2003
|Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system|
A Koussounadis, SP Langdon, IH Um, DJ Harrison, VA Smith
Scientific reports 5 (1), 1-9, 2015
|Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning|
J McWhir, J Selfridge, DJ Harrison, S Squires, DW Melton
Nature genetics 5 (3), 217-224, 1993
|WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis|
JK Guo, AL Menke, MC Gubler, AR Clarke, D Harrison, A Hammes, ...
Human molecular genetics 11 (6), 651-659, 2002
|Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression|
T Latham, L Mackay, D Sproul, M Karim, J Culley, DJ Harrison, L Hayward, ...
Nucleic Acids Research 40 (11), 4794-4803, 2012
|Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members|
T O'CONNOR, LS Ireland, DJ Harrison, JD Hayes
Biochemical journal 343 (2), 487-504, 1999
|Counting alleles to predict recurrence of early-stage colorectal cancers|
W Zhou, SN Goodman, G Galizia, E Lieto, F Ferraraccio, C Pignatelli, ...
The Lancet 359 (9302), 219-225, 2002
|Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases|
SJ Aitken, JS Thomas, SP Langdon, DJ Harrison, D Faratian
Annals of Oncology 21 (6), 1254-1261, 2010
|Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study|
GD Stewart, L Van Neste, P Delvenne, P Delrée, A Delga, SA McNeill, ...
The Journal of urology 189 (3), 1110-1116, 2013
|Induction of γ‐glutamylcysteine synthetase by cigarette smoke is associated with AP‐1 in human alveolar epithelial cells|
I Rahman, CAD Smith, MF Lawson, DJ Harrison, W MacNee
FEBS letters 396 (1), 21-25, 1996
|Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress|
I Rahman, XY Li, K Donaldson, DJ Harrison, W MacNee
American Journal of Physiology-Lung Cellular and Molecular Physiology 269 (3 …, 1995
|New strategies for targeting the hypoxic tumour microenvironment in breast cancer|
C Ward, SP Langdon, P Mullen, AL Harris, DJ Harrison, CT Supuran, ...
Cancer treatment reviews 39 (2), 171-179, 2013