| Structural interaction fingerprint (SIFt): a novel method for analyzing three-dimensional protein− ligand binding interactions Z Deng, C Chuaqui, J Singh Journal of medicinal chemistry 47 (2), 337-344, 2004 | 661 | 2004 |
| Structure-and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR) RA Ward, MJ Anderton, S Ashton, PA Bethel, M Box, S Butterworth, ... Journal of medicinal chemistry 56 (17), 7025-7048, 2013 | 281 | 2013 |
| Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI) J Singh, CE Chuaqui, PA Boriack-Sjodin, WC Lee, T Pontz, MJ Corbley, ... Bioorganic & medicinal chemistry letters 13 (24), 4355-4359, 2003 | 231 | 2003 |
| Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain G Akçay, MA Belmonte, B Aquila, C Chuaqui, AW Hird, ML Lamb, ... Nature chemical biology 12 (11), 931-936, 2016 | 201 | 2016 |
| Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1 J Wu, K Mikule, W Wang, N Su, P Petteruti, F Gharahdaghi, E Code, X Zhu, ... ACS chemical biology 8 (10), 2201-2208, 2013 | 167 | 2013 |
| Infrared spectrum and potential energy surface of He–CO CE Chuaqui, RJ Le Roy, ARW McKellar The Journal of chemical physics 101 (1), 39-61, 1994 | 157 | 1994 |
| Interaction profiles of protein kinase− inhibitor complexes and their application to virtual screening C Chuaqui, Z Deng, J Singh Journal of medicinal chemistry 48 (1), 121-133, 2005 | 119 | 2005 |
| SM16, an orally active TGF-β type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model K Fu, MJ Corbley, L Sun, JE Friedman, F Shan, JL Papadatos, D Costa, ... Arteriosclerosis, thrombosis, and vascular biology 28 (4), 665-671, 2008 | 89 | 2008 |
| Knowledge-based design of target-focused libraries using protein− ligand interaction constraints Z Deng, C Chuaqui, J Singh Journal of medicinal chemistry 49 (2), 490-500, 2006 | 84 | 2006 |
| Structural interaction fingerprints: a new approach to organizing, mining, analyzing, and designing protein–small molecule complexes J Singh, Z Deng, G Narale, C Chuaqui Chemical Biology & Drug Design 67 (1), 5-12, 2006 | 80 | 2006 |
| A reliable new potential energy surface for H2–Ar C Bissonnette, CE Chuaqui, KG Crowell, RJ Le Roy, RJ Wheatley, ... The Journal of chemical physics 105 (7), 2639-2653, 1996 | 72 | 1996 |
| Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors W McCoull, RD Abrams, E Anderson, K Blades, P Barton, M Box, ... Journal of Medicinal Chemistry 60 (10), 4386-4402, 2017 | 70 | 2017 |
| Discovery of 1-Methyl-1H-imidazole Derivatives as Potent Jak2 Inhibitors Q Su, S Ioannidis, C Chuaqui, L Almeida, M Alimzhanov, G Bebernitz, ... Journal of medicinal chemistry 57 (1), 144-158, 2014 | 60 | 2014 |
| Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo JE Dowling, M Alimzhanov, L Bao, C Chuaqui, CR Denz, E Jenkins, ... ACS Medicinal Chemistry Letters 7 (3), 300-305, 2016 | 56 | 2016 |
| Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases T Wang, MA Block, S Cowen, AM Davies, E Devereaux, L Gingipalli, ... Bioorganic & medicinal chemistry letters 22 (5), 2063-2069, 2012 | 56 | 2012 |
| Linewidths and shifts of very low temperature CO in He: A challenge for theory or experiment? M Thachuk, CE Chuaqui, RJ Le Roy The Journal of chemical physics 105 (10), 4005-4014, 1996 | 53 | 1996 |
| Discovery of SY-5609: a selective, noncovalent inhibitor of CDK7 JJ Marineau, KB Hamman, S Hu, S Alnemy, J Mihalich, A Kabro, ... Journal of Medicinal Chemistry 65 (2), 1458-1480, 2021 | 52 | 2021 |
| Structure and property based design of pyrazolo [1, 5-a] pyrimidine inhibitors of CK2 kinase with activity in vivo JE Dowling, M Alimzhanov, L Bao, MH Block, C Chuaqui, EL Cooke, ... ACS medicinal chemistry letters 4 (8), 800-805, 2013 | 50 | 2013 |
| Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening B Yang, ML Lamb, T Zhang, EJ Hennessy, G Grewal, L Sha, ... Journal of medicinal chemistry 57 (23), 9958-9970, 2014 | 49 | 2014 |
| Potent and selective inhibitors of CK2 kinase identified through structure-guided hybridization JE Dowling, C Chuaqui, TW Pontz, PD Lyne, NA Larsen, MH Block, ... ACS Medicinal Chemistry Letters 3 (4), 278-283, 2012 | 47 | 2012 |
Marat AlimzhanovEMD SeronoVerified email at emdserono.com
