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Youmna Kfoury
Youmna Kfoury
Center for Regenrative Medicine, MGH
Geverifieerd e-mailadres voor mgh.harvard.edu
Titel
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Jaar
A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia
N Baryawno, D Przybylski, MS Kowalczyk, Y Kfoury, N Severe, ...
Cell 177 (7), 1915-1932. e16, 2019
6732019
Mesenchymal cell contributions to the stem cell niche
Y Kfoury, DT Scadden
Cell stem cell 16 (3), 239-253, 2015
5702015
Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia
DB Sykes, YS Kfoury, FE Mercier, MJ Wawer, JM Law, MK Haynes, ...
Cell 167 (1), 171-186. e15, 2016
4362016
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
R Palchaudhuri, B Saez, J Hoggatt, A Schajnovitz, DB Sykes, TA Tate, ...
Nature biotechnology 34 (7), 738-745, 2016
2212016
Hematopoietic stem cell niche in health and disease
J Hoggatt, Y Kfoury, DT Scadden
Annual Review of Pathology: Mechanisms of Disease 11, 555-581, 2016
1712016
Proximity-based differential single-cell analysis of the niche to identify stem/progenitor cell regulators
L Silberstein, KA Goncalves, PV Kharchenko, R Turcotte, Y Kfoury, ...
Cell stem cell 19 (4), 530-543, 2016
1582016
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-κB activation
R Nasr, E Chiari, M El-Sabban, R Mahieux, Y Kfoury, M Abdulhay, ...
Blood 107 (10), 4021-4029, 2006
1222006
Stress-induced changes in bone marrow stromal cell populations revealed through single-cell protein expression mapping
N Severe, NM Karabacak, K Gustafsson, N Baryawno, G Courties, ...
Cell stem cell 25 (4), 570-583. e7, 2019
1102019
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Y Kfoury, N Baryawno, N Severe, S Mei, K Gustafsson, T Hirz, T Brouse, ...
Cancer cell 39 (11), 1464-1478. e8, 2021
1082021
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia
H El Hajj, M El-Sabban, H Hasegawa, G Zaatari, J Ablain, ST Saab, ...
Journal of Experimental Medicine 207 (13), 2785-2792, 2010
1032010
Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma
R Nasr, ME El-Sabban, JA Karam, G Dbaibo, Y Kfoury, B Arnulf, ...
Oncogene 24 (3), 419-430, 2005
101*2005
Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome
Y Kfoury, R Nasr, A Favre-Bonvin, M El-Sabban, N Renault, ML Giron, ...
Oncogene 27 (12), 1665-1676, 2008
872008
ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation
Z Dassouki, U Sahin, H El Hajj, F Jollivet, Y Kfoury, ...
Blood, The Journal of the American Society of Hematology 125 (3), 474-482, 2015
752015
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome
Y Kfoury, N Setterblad, M El-Sabban, A Zamborlini, Z Dassouki, H El Hajj, ...
Blood, The Journal of the American Society of Hematology 117 (1), 190-199, 2011
632011
Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide …
GS Dbaibo, Y Kfoury, N Darwiche, S Panjarian, L Kozhaya, R Nasr, ...
haematologica 92 (6), 753-762, 2007
582007
The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation
Y Kfoury, R Nasr, C Journo, R Mahieux, C Pique, A Bazarbachi
Advances in cancer research 113, 85-120, 2012
562012
Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway.
Y Kfoury, R Nasr, O Hermine, A Bazarbachi
Cell death and differentiation 12, 871-877, 2004
54*2004
EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I–associated adult T-cell leukemia …
G Moarbess, H El-Hajj, Y Kfoury, ME El-Sabban, Y Lepelletier, O Hermine, ...
Blood, The Journal of the American Society of Hematology 111 (7), 3770-3777, 2008
492008
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
T Hirz, S Mei, H Sarkar, Y Kfoury, S Wu, BM Verhoeven, AO Subtelny, ...
Nature Communications 14 (1), 663, 2023
452023
Animal models on HTLV-1 and related viruses: what did we learn?
HE Hajj, R Nasr, Y Kfoury, Z Dassouki, R Nasser, G Kchour, O Hermine, ...
Frontiers in microbiology 3, 333, 2012
452012
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Artikelen 1–20