Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy AM Bradbury, JN Cochran, VJ McCurdy, AK Johnson, BL Brunson, ... Molecular Therapy 21 (7), 1306-1315, 2013 | 91 | 2013 |
Adeno-associated virus gene therapy in a sheep model of Tay–Sachs disease HL Gray-Edwards, AN Randle, SA Maitland, HR Benatti, SM Hubbard, ... Human Gene Therapy 29 (3), 312-326, 2018 | 88 | 2018 |
Sustained normalization of neurological disease after intracranial gene therapy in a feline model VJ McCurdy, AK Johnson, HL Gray-Edwards, AN Randle, BL Brunson, ... Science translational medicine 6 (231), 231ra48-231ra48, 2014 | 76 | 2014 |
Widespread correction of central nervous system disease after intracranial gene therapy in a feline model of Sandhoff disease VJ McCurdy, HE Rockwell, JR Arthur, AM Bradbury, AK Johnson, ... Gene therapy 22 (2), 181-189, 2015 | 74 | 2015 |
The anti-tumor activity of anti-CTLA-4 is mediated through its induction of IFNγ TJ Paradis, E Floyd, J Burkwit, SH Cole, B Brunson, E Elliott, S Gilman, ... Cancer Immunology, Immunotherapy 50, 125-133, 2001 | 53 | 2001 |
Increased total and high–molecular weight adiponectin after extended-release niacin EP Plaisance, PW Grandjean, BL Brunson, RL Judd Metabolism 57 (3), 404-409, 2008 | 46 | 2008 |
Endothelin-1 inhibits adiponectin secretion through a phosphatidylinositol 4, 5-bisphosphate/actin-dependent mechanism D Bedi, KJ Clarke, JC Dennis, Q Zhong, BL Brunson, EE Morrison, ... Biochemical and biophysical research communications 345 (1), 332-339, 2006 | 41 | 2006 |
Serum concentrations of adiponectin and characterization of adiponectin protein complexes in dogs BL Brunson, Q Zhong, KJ Clarke, D Bedi, TD Braden, E van Santen, ... American journal of veterinary research 68 (1), 57-62, 2007 | 40 | 2007 |
Novel biomarkers of human GM1 gangliosidosis reflect the clinical efficacy of gene therapy in a feline model HL Gray-Edwards, DS Regier, JL Shirley, AN Randle, N Salibi, ... Molecular Therapy 25 (4), 892-903, 2017 | 37 | 2017 |
Mucopolysaccharidosis-like phenotype in feline Sandhoff disease and partial correction after AAV gene therapy HL Gray-Edwards, BL Brunson, M Holland, AM Hespel, AM Bradbury, ... Molecular genetics and metabolism 116 (1-2), 80-87, 2015 | 35 | 2015 |
Biomarkers for disease progression and AAV therapeutic efficacy in feline Sandhoff disease AM Bradbury, HL Gray-Edwards, JL Shirley, VJ McCurdy, AN Colaco, ... Experimental neurology 263, 102-112, 2015 | 33 | 2015 |
AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease AM Bradbury, TA Peterson, AL Gross, SZ Wells, VJ McCurdy, KG Wolfe, ... Neuroscience 340, 117-125, 2017 | 28 | 2017 |
7T MRI predicts amelioration of neurodegeneration in the brain after AAV gene therapy HL Gray-Edwards, AS Maguire, N Salibi, LE Ellis, TL Voss, EB Diffie, ... Molecular Therapy-Methods & Clinical Development 17, 258-270, 2020 | 20 | 2020 |
Vascular hamartoma in the tongue of a horse BL Brunson, J Taintor, J Newton, J Schumacher, U Christman Journal of equine veterinary science 26 (6), 275-277, 2006 | 10 | 2006 |
Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis AL Gross, HL Gray-Edwards, CN Bebout, NL Ta, K Nielsen, BL Brunson, ... Brain 145 (2), 655-669, 2022 | 8 | 2022 |
Intracranial AAV gene therapy extends the life span of GM2 gangliosidosis cats> four-fold with no clinical evidence of vector toxicity AM Bradbury, VJ McCurdy, AK Johnson, H Gray-Edwards, BL Brunson, ... Molecular Therapy 21, S226-S226, 2013 | 3 | 2013 |
605. Cerebrospinal Fluid for Delivery of AAV Gene Therapy in GM1 Gangliosidosis AL Gross, H Gray-Edwards, B Murdock, A Taylor, B Brunson, AN Randle, ... Molecular Therapy 24, S240, 2016 | 1 | 2016 |
Characterization of adiponectin in the canine BL Brunson Auburn University, 2007 | 1 | 2007 |
Life‐Limiting Peripheral Organ Dysfunction in Feline Sandhoff Disease Emerges after Effective CNS Gene Therapy AK Johnson, VJ McCurdy, HL Gray‐Edwards, AS Maguire, JN Cochran, ... Annals of Neurology 94 (5), 969-986, 2023 | | 2023 |
Intravenous Delivery of AAV Gene Therapy in GM1 Gangliosidosis AL Gross, HL Gray-Edwards, CN Bebout, K Neilson, BL Brunson, ... MOLECULAR THERAPY 27 (4), 191-191, 2019 | | 2019 |