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Lasse Staby
Lasse Staby
Verified email at bio.ku.dk
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Year
Eukaryotic transcription factors: paradigms of protein intrinsic disorder
L Staby, C O'Shea, M Willemoës, F Theisen, BB Kragelund, K Skriver
Biochemical Journal 474 (15), 2509-2532, 2017
1262017
Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub protein radical-induced cell death1
C O'Shea, L Staby, SK Bendsen, FG Tidemand, A Redsted, M Willemoës, ...
Journal of Biological Chemistry 292 (2), 512-527, 2017
572017
Temperature Dependence of Intrinsically Disordered Proteins in Simulations: What are We Missing?
S Jephthah, L Staby, BB Kragelund, M Skepö
Journal of chemical theory and computation 15 (4), 2672-2683, 2019
542019
Characterization of dynamic IDP complexes by NMR spectroscopy
A Prestel, K Bugge, L Staby, R Hendus-Altenburger, BB Kragelund
Methods in enzymology 611, 193-226, 2018
342018
Structure of radical-induced cell death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks
K Bugge, L Staby, KR Kemplen, C O'Shea, SK Bendsen, MK Jensen, ...
Structure 26 (5), 734-746. e7, 2018
282018
Dynamical oligomerisation of histidine rich intrinsically disordered proteins is regulated through zinc-histidine interactions
C Cragnell, L Staby, S Lenton, BB Kragelund, M Skepö
Biomolecules 9 (5), 168, 2019
242019
Quantification of conformational entropy unravels effect of disordered flanking region in coupled folding and binding
FF Theisen, L Staby, FG Tidemand, C O’Shea, A Prestel, M Willemoes, ...
Journal of the American Chemical Society 143 (36), 14540-14550, 2021
212021
Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome
LF Christensen, L Staby, K Bugge, C O’Shea, BB Kragelund, K Skriver
Scientific reports 9 (1), 1-15, 2019
202019
αα-hub domains and intrinsically disordered proteins–a decisive combo
K Bugge, L Staby, E Salladini, RG Falbe-Hansen, BB Kragelund, ...
Journal of Biological Chemistry, jbc. REV120. 012928, 2020
172020
Flanking disorder of the folded αα-hub domain from radical induced cell death1 affects transcription factor binding by ensemble redistribution
L Staby, AD Due, MBA Kunze, MLM Jørgensen, K Skriver, BB Kragelund
Journal of Molecular Biology 433 (24), 167320, 2021
152021
Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime
S Elkjær, AD Due, LF Christensen, FF Theisen, L Staby, BB Kragelund, ...
Communications Biology 6 (1), 63, 2023
112023
Connecting the αα-hubs: same fold, disordered ligands, new functions
L Staby, K Bugge, RG Falbe-Hansen, E Salladini, K Skriver, ...
Cell Communication and Signaling 19 (1), 1-5, 2021
92021
Αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes
FF Theisen, E Salladini, R Davidsen, CJ Rasmussen, L Staby, ...
Journal of Biological Chemistry 298 (6), 2022
72022
Disorder in a two-domain neuronal Ca 2+-binding protein regulates domain stability and dynamics using ligand mimicry
L Staby, KR Kemplen, A Stein, M Ploug, J Clarke, K Skriver, ...
Cellular and Molecular Life Sciences, 1-16, 2020
42020
A glutamine-based single α-helix scaffold to target globular proteins
A Escobedo, J Piccirillo, J Aranda, T Diercks, B Mateos, C Garcia-Cabau, ...
Nature communications 13 (1), 7073, 2022
32022
Effects of Salt or Cosolvent Addition on Thermal Stability of a Protein: Relevance to those on Solubility of a Hydrophobic Solute in Water
S Murakami, T Hayashi, M Kinoshita
Biophysical journal 112 (3), 58a, 2017
22017
Selection by disorder in the folded cellular hub Radical-Induced Cell Death1
L Staby
Department of Biology, Faculty of Science, University of Copenhagen, 2019
2019
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Articles 1–17