Thomas Blacker
Thomas Blacker
Research Associate, University College London
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Cellular and molecular mechanisms of mitochondrial function
LD Osellame, TS Blacker, MR Duchen
Best Practice & Research Clinical Endocrinology & Metabolism 26 (6), 711-723, 2012
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
TS Blacker, ZF Mann, JE Gale, M Ziegler, AJ Bain, G Szabadkai, ...
Nature communications 5, 3936, 2014
Investigating mitochondrial redox state using NADH and NADPH autofluorescence
TS Blacker, MR Duchen
Free Radical Biology and Medicine 100, 53-65, 2016
Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure
AG Nickel, A von Hardenberg, M Hohl, JR Löffler, M Kohlhaas, J Becker, ...
Cell metabolism 22 (3), 472-484, 2015
The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α
A Tosatto, R Sommaggio, C Kummerow, RB Bentham, TS Blacker, ...
EMBO Molecular Medicine 8 (5), 569-585, 2016
NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction
E Gaude, C Schmidt, PA Gammage, A Dugourd, T Blacker, SP Chew, ...
Molecular cell 69 (4), 581-593. e7, 2018
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells
E Haythorne, M Rohm, M van de Bunt, MF Brereton, AI Tarasov, ...
Nature communications 10 (1), 1-17, 2019
Activated barrier crossing dynamics in the non-radiative decay of NADH and NADPH
TS Blacker, RJ Marsh, MR Duchen, AJ Bain
Chemical Physics 422, 184-194, 2013
CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism
LW Thomas, C Esposito, JM Stephen, ASH Costa, C Frezza, TS Blacker, ...
Cancer & metabolism 7 (1), 1-17, 2019
Polarized Two-Photon Absorption and Heterogeneous Fluorescence Dynamics in NAD (P) H
TS Blacker, N Nicolaou, MR Duchen, AJ Bain
The Journal of Physical Chemistry B 123 (22), 4705-4717, 2019
Photoactivated cell-killing involving a low molecular weight, donor–acceptor diphenylacetylene
DR Chisholm, R Lamb, T Pallett, V Affleck, C Holden, J Marrison, ...
Chemical science 10 (17), 4673-4683, 2019
Decellularized Cartilage Directs Chondrogenic Differentiation: Creation of a Fracture Callus Mimetic
WJ Vas, M Shah, TS Blacker, MR Duchen, P Sibbons, SJ Roberts
Tissue Engineering Part A 24 (17-18), 1364-1376, 2018
Investigating State Restriction in Fluorescent Protein FRET Using Time-Resolved Fluorescence and Anisotropy
TS Blacker, WY Chen, E Avezov, RJ Marsh, MR Duchen, CF Kaminski, ...
The Journal of Physical Chemistry C 121 (3), 1507–1514, 2017
Assessment of Cellular Redox State Using NAD (P) H Fluorescence Intensity and Lifetime
TS Blacker, T Berecz, MR Duchen, G Szabadkai
Bio-protocol 7 (2), 2017
Polarized two-photon photoselection in EGFP: Theory and experiment
TA Masters, RJ Marsh, TS Blacker, DA Armoogum, B Larijani, AJ Bain
The Journal of Chemical Physics 148 (13), 134311, 2018
Metabolic Profiling of Live Cancer Tissues Using NAD (P) H Fluorescence Lifetime Imaging
TS Blacker, MDE Sewell, G Szabadkai, MR Duchen
Cancer Metabolism, 365-387, 2019
Time-resolved stimulated emission depletion and energy transfer dynamics in two-photon excited EGFP
TA Masters, NA Robinson, RJ Marsh, TS Blacker, DA Armoogum, ...
The Journal of Chemical Physics 148 (13), 134312, 2018
Characterizing Metabolic States Using Fluorescence Lifetime Imaging Microscopy (FLIM) of NAD (P) H
TS Blacker, MR Duchen
Techniques to Investigate Mitochondrial Function in Neurons, 133-150, 2017
Cellular localisation of structurally diverse diphenylacetylene fluorophores
DR Chisholm, JG Hughes, TS Blacker, R Humann, C Adams, ...
Organic & Biomolecular Chemistry 18 (45), 9231-9245, 2020
Multiphoton NAD (P) H FLIM reveals metabolic changes in individual cell types of the intact cochlea upon sensorineural hearing loss
P Majumder, TS Blacker, LS Nolan, MR Duchen, JE Gale
Scientific Reports 9 (1), 1-10, 2019
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