Laura Blair
Laura Blair
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LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ...
Journal of neuroinflammation 7 (1), 1-16, 2010
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ...
The Journal of clinical investigation 123 (10), 4158-4169, 2013
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
Journal of Neuroscience 33 (22), 9498-9507, 2013
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
Journal of Neuroscience 30 (2), 591-599, 2010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5 (1), 1-11, 2010
DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ...
The EMBO journal 35 (14), 1537-1549, 2016
Chaperone signalling complexes in Alzheimer's disease
J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ...
Journal of cellular and molecular medicine 13 (4), 619-630, 2009
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
LJ Blair, HD Frauen, B Zhang, BA Nordhues, S Bijan, YC Lin, F Zamudio, ...
Acta neuropathologica communications 3 (1), 1-22, 2015
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450-1459, 2013
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51
JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ...
PloS one 6 (9), e24840, 2011
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
Journal of Neuroscience 30 (46), 15374-15382, 2010
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren III, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of biological chemistry 285 (4), 2498-2505, 2010
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary III, SI Borysov, JR Jones, Q Li, J Koren III, ...
Journal of biological chemistry 285 (22), 16798-16805, 2010
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy
C Dickey, C Kraft, U Jinwal, J Koren, A Johnson, L Anderson, L Lebson, ...
The American journal of pathology 174 (1), 228, 2009
The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease
LJ Blair, JD Baker, JJ Sabbagh, CA Dickey
Journal of neurochemistry 133 (1), 1-13, 2015
Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease
LJ Blair, JJ Sabbagh, CA Dickey
Expert opinion on therapeutic targets 18 (10), 1219-1232, 2014
Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency
JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ...
PloS one 9 (9), e107241, 2014
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism
A Suntharalingam, JF Abisambra, JC O'Leary III, J Koren III, B Zhang, ...
Journal of Biological Chemistry 287 (48), 40661-40669, 2012
The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau
JR Jones, MD Lebar, UK Jinwal, JF Abisambra, J Koren III, L Blair, ...
Journal of natural products 74 (1), 38-44, 2011
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