| Quantitative analysis of complex protein mixtures using isotope-coded affinity tags SP Gygi, B Rist, SA Gerber, F Turecek, MH Gelb, R Aebersold Nature biotechnology 17 (10), 994-999, 1999 | 6580 | 1999 |
| A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis P Boström, J Wu, MP Jedrychowski, A Korde, L Ye, JC Lo, KA Rasbach, ... Nature 481 (7382), 463-468, 2012 | 5410 | 2012 |
| Correlation between protein and mRNA abundance in yeast SP Gygi, Y Rochon, BR Franza, R Aebersold Molecular and cellular biology, 1999 | 5079 | 1999 |
| The impact of microRNAs on protein output D Baek, J Villén, C Shin, FD Camargo, SP Gygi, DP Bartel Nature 455 (7209), 64-71, 2008 | 4386 | 2008 |
| Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry JE Elias, SP Gygi Nature methods 4 (3), 207-214, 2007 | 4170 | 2007 |
| Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 JT Rodgers, C Lerin, W Haas, SP Gygi, BM Spiegelman, P Puigserver Nature 434 (7029), 113-118, 2005 | 3793 | 2005 |
| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ... science 303 (5666), 2011-2015, 2004 | 3773 | 2004 |
| ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage S Matsuoka, BA Ballif, A Smogorzewska, ER McDonald III, KE Hurov, ... science 316 (5828), 1160-1166, 2007 | 3538 | 2007 |
| Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer K Rikova, A Guo, Q Zeng, A Possemato, J Yu, H Haack, J Nardone, K Lee, ... Cell 131 (6), 1190-1203, 2007 | 2735 | 2007 |
| Identification of a unique TGF-β–dependent molecular and functional signature in microglia O Butovsky, MP Jedrychowski, CS Moore, R Cialic, AJ Lanser, G Gabriely, ... Nature neuroscience 17 (1), 131-143, 2014 | 2490 | 2014 |
| Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS SA Gerber, J Rush, O Stemman, MW Kirschner, SP Gygi Proceedings of the National Academy of Sciences 100 (12), 6940-6945, 2003 | 2269 | 2003 |
| A proteomics approach to understanding protein ubiquitination J Peng, D Schwartz, JE Elias, CC Thoreen, D Cheng, G Marsischky, ... Nature biotechnology 21 (8), 921-926, 2003 | 2015 | 2003 |
| Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology SP Gygi, GL Corthals, Y Zhang, Y Rochon, R Aebersold Proceedings of the National Academy of Sciences 97 (17), 9390-9395, 2000 | 1978 | 2000 |
| Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC− MS/MS) for large-scale protein analysis: the yeast proteome J Peng, JE Elias, CC Thoreen, LJ Licklider, SP Gygi Journal of proteome research 2 (1), 43-50, 2003 | 1966 | 2003 |
| A quantitative atlas of mitotic phosphorylation N Dephoure, C Zhou, J Villén, SA Beausoleil, CE Bakalarski, SJ Elledge, ... Proceedings of the National Academy of Sciences 105 (31), 10762-10767, 2008 | 1904 | 2008 |
| A tissue-specific atlas of mouse protein phosphorylation and expression EL Huttlin, MP Jedrychowski, JE Elias, T Goswami, R Rad, SA Beausoleil, ... Cell 143 (7), 1174-1189, 2010 | 1777 | 2010 |
| Systematic and quantitative assessment of the ubiquitin-modified proteome W Kim, EJ Bennett, EL Huttlin, A Guo, J Li, A Possemato, ME Sowa, ... Molecular cell 44 (2), 325-340, 2011 | 1765 | 2011 |
| Large-scale characterization of HeLa cell nuclear phosphoproteins SA Beausoleil, M Jedrychowski, D Schwartz, JE Elias, J Villén, J Li, ... Proceedings of the National Academy of Sciences 101 (33), 12130-12135, 2004 | 1708 | 2004 |
| Network organization of the human autophagy system C Behrends, ME Sowa, SP Gygi, JW Harper Nature 466 (7302), 68-76, 2010 | 1688 | 2010 |
| A probability-based approach for high-throughput protein phosphorylation analysis and site localization SA Beausoleil, J Villén, SA Gerber, J Rush, SP Gygi Nature biotechnology 24 (10), 1285-1292, 2006 | 1680 | 2006 |
