Alexander Skupin
Alexander Skupin
Luxembourg Centre for Systems Biomedicine, University Luxembourg
Geverifieerd e-mailadres voor uni.lu - Homepage
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Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival
A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ...
PloS one 10 (5), e0126522, 2015
2742015
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ...
Nature communications 10 (1), 1-16, 2019
2222019
Cell fate decision as high-dimensional critical state transition
M Mojtahedi, A Skupin, J Zhou, IG Castaño, RYY Leong-Quong, H Chang, ...
PLoS biology 14 (12), e2000640, 2016
2102016
How does intracellular Ca2+ oscillate: by chance or by the clock?
A Skupin, H Kettenmann, U Winkler, M Wartenberg, H Sauer, SC Tovey, ...
Biophysical journal 94 (6), 2404-2411, 2008
1852008
Pro-inflammatory macrophages sustain pyruvate oxidation through pyruvate dehydrogenase for the synthesis of itaconate and to enable cytokine expression
J Meiser, L Krämer, SC Sapcariu, N Battello, J Ghelfi, AF D'Herouel, ...
Journal of Biological Chemistry 291 (8), 3932-3946, 2016
1382016
Clustering of InsP 3 receptors by InsP 3 retunes their regulation by InsP 3 and Ca 2+
A Skupin, M Falcke, CW Taylor
Nature 458 (7238), 655-659, 2009
1162009
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ...
EMBO reports 19 (11), e46171, 2018
1022018
Calcium signals driven by single channel noise
A Skupin, H Kettenmann, M Falcke
PLoS computational biology 6 (8), e1000870, 2010
992010
Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes
K Thurley, SC Tovey, G Moenke, VL Prince, A Meena, AP Thomas, ...
Science signaling 7 (331), ra59-ra59, 2014
922014
Fundamental properties of Ca2+ signals
K Thurley, A Skupin, R Thul, M Falcke
Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (8), 1185-1194, 2012
872012
Critical transitions in chronic disease: transferring concepts from ecology to systems medicine
C Trefois, PMA Antony, J Goncalves, A Skupin, R Balling
Current opinion in biotechnology 34, 48-55, 2015
762015
Aneuploidy underlies a multicellular phenotypic switch
Z Tan, M Hays, GA Cromie, EW Jeffery, AC Scott, V Ahyong, A Sirr, ...
Proceedings of the National Academy of Sciences 110 (30), 12367-12372, 2013
702013
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1/ zebrafish
S Soman, M Keatinge, M Moein, M Da Costa, H Mortiboys, A Skupin, ...
European Journal of Neuroscience 45 (4), 528-535, 2017
572017
Protocols and programs for high-throughput growth and aging phenotyping in yeast
PP Jung, N Christian, DP Kay, A Skupin, CL Linster
PloS one 10 (3), e0119807, 2015
522015
From puffs to global signals: How molecular properties shape global signals
A Skupin, M Falcke
Chaos: An Interdisciplinary Journal of Nonlinear Science 19 (3), 037111, 2009
502009
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality
J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ...
Stem cell reports 12 (5), 878-889, 2019
452019
Temperature and nitric oxide control spontaneous calcium transients in astrocytes
CG Schipke, A Heidemann, A Skupin, O Peters, M Falcke, H Kettenmann
Cell calcium 43 (3), 285-295, 2008
432008
Carbohydrate‐active enzymes exemplify entropic principles in metabolism
Ö Kartal, S Mahlow, A Skupin, O Ebenhöh
Molecular systems biology 7 (1), 542, 2011
422011
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
J Meiser, S Delcambre, A Wegner, C Jäger, J Ghelfi, AF d'Herouel, ...
Neurobiology of disease 89, 112-125, 2016
332016
Describing the complexity of systems: Multivariable “set complexity” and the information basis of systems biology
DJ Galas, NA Sakhanenko, A Skupin, T Ignac
Journal of Computational Biology 21 (2), 118-140, 2014
312014
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Artikelen 1–20