| Chromatographic hydrophobicity index by fast-gradient RP-HPLC: a high-throughput alternative to log P/log D K Valkó, C Bevan, D Reynolds Analytical chemistry 69 (11), 2022-2029, 1997 | 476 | 1997 |
| Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity K Valko, S Nunhuck, C Bevan, MH Abraham, DP Reynolds Journal of pharmaceutical sciences 92 (11), 2236-2248, 2003 | 394 | 2003 |
| An excellent reagent for the removal of the t-butyldimethylsilyl protecting group RF Newton, DP Reynolds, MAW Finch, DR Kelly, SM Roberts Tetrahedron Letters 20 (41), 3981-3982, 1979 | 265 | 1979 |
| Application of hydrogen bonding calculations in property based drug design MH Abraham, A Ibrahim, AM Zissimos, YH Zhao, J Comer, DP Reynolds Drug Discovery Today 7 (20), 1056-1063, 2002 | 207 | 2002 |
| Rapid method for the estimation of octanol/water partition coefficient (log Poct) from gradient RP-HPLC retention and a hydrogen bond acidity term (Sigma alpha2H) K Valko, C Du, C Bevan, DP Reynolds, MH Abraham Current medicinal chemistry 8 (9), 1137-1146, 2001 | 189 | 2001 |
| Rapid‐gradient HPLC method for measuring drug interactions with immobilized artificial membrane: Comparison with other lipophilicity measures K Valko, CM Du, CD Bevan, DP Reynolds, MH Abraham Journal of pharmaceutical sciences 89 (8), 1085-1096, 2000 | 180 | 2000 |
| Rapid gradient RP-HPLC method for lipophilicity determination: a solvation equation based comparison with isocratic methods CM Du, K Valko, C Bevan, D Reynolds, MH Abraham Analytical Chemistry 70 (20), 4228-4234, 1998 | 173 | 1998 |
| Predicting penetration across the blood-brain barrier from simple descriptors and fragmentation schemes YH Zhao, MH Abraham, A Ibrahim, PV Fish, S Cole, ML Lewis, ... Journal of chemical information and modeling 47 (1), 170-175, 2007 | 156 | 2007 |
| Relationships between the chromatographic hydrophobicity indices and solute descriptors obtained by using several reversed-phase, diol, nitrile, cyclodextrin and immobilised … K Valko, M Plass, C Bevan, D Reynolds, MH Abraham Journal of chromatography A 797 (1-2), 41-55, 1998 | 150 | 1998 |
| High-Throughput Measurement of pKa Values in a Mixed-Buffer Linear pH Gradient System K Box, C Bevan, J Comer, A Hill, R Allen, D Reynolds Analytical chemistry 75 (4), 883-892, 2003 | 131 | 2003 |
| Calculation of Abraham descriptors from experimental data from seven HPLC systems; evaluation of five different methods of calculation AM Zissimos, MH Abraham, CM Du, K Valko, C Bevan, D Reynolds, ... Journal of the Chemical Society, Perkin Transactions 2, 2001-2010, 2002 | 123 | 2002 |
| Characterizing the selectivity of stationary phases and organic modifiers in reversed-phase high-performance liquid chromatographic systems by a general solvation equation … CM Du, K Valko, C Bevan, D Reynolds, MH Abraham Journal of chromatographic science 38 (11), 503-511, 2000 | 85 | 2000 |
| On the mechanism of human intestinal absorption MH Abraham, YH Zhao, J Le, A Hersey, CN Luscombe, DP Reynolds, ... European journal of medicinal chemistry 37 (7), 595-605, 2002 | 83 | 2002 |
| Ionization-specific analysis of human intestinal absorption DP Reynolds, K Lanevskij, P Japertas, R Didziapetris, A Petrauskas Journal of pharmaceutical sciences 98 (11), 4039-4054, 2009 | 44 | 2009 |
| RAPID METHOD FOR ESTIMATING OCTANOL-WATER PARTITION COEFFICIENT (LOG POCT) FROM ISOCRATIC RP-HPLC AND A HYDROGEN BOND … CM Du, K Valko, C Bevan, D Reynolds, MH Abraham Journal of liquid chromatography & related technologies 24 (5), 635-649, 2001 | 40 | 2001 |
| High-throughput physicochemical and in vitro ADMET screening: A role in pharmaceutical profiling K Valko, DP Reynolds American Journal of Drug Delivery 3, 83-100, 2005 | 25 | 2005 |
| Enantio-complementary total asymmetric syntheses of prostaglandin E 2 and prostaglandin F 2α J Davies, SM Roberts, DP Reynolds, RF Newton Journal of the Chemical Society, Perkin Transactions 1, 1317-1320, 1981 | 24 | 1981 |
| Substrate non-enantiospecific and product enantioselective reduction of bicyclo [3.2. 0] hept-2-en-6-one using yeast RF Newton, J Paton, DP Reynolds, S Young, SM Roberts Journal of the Chemical Society, Chemical Communications, 908-909, 1979 | 23 | 1979 |
| A short and efficient total synthesis of (±) prostaglandin D 2 methyl ester involving a new method for the cleavage of a dimethyl-t-butylsilyl ether RF Newton, DP Reynolds, CF Webb, SM Roberts Journal of the Chemical Society, Perkin Transactions 1, 2055-2058, 1981 | 20 | 1981 |
| In silico technology for identification of potentially toxic compounds in drug discovery R Didziapetris, DP Reynolds, P Japertas, D Zmuidinavicius, A Petrauskas Current Computer-Aided Drug Design 2 (2), 95-103, 2006 | 18 | 2006 |
Klara ValkoDirector, Honorary Professor UCL School of PharmacyVerified email at ucl.ac.uk
