Brian Law, Ph.D.
Brian Law, Ph.D.
Associate Professor of Pharmacology, University of Florida
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Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription
ME Engel, MA McDonnell, BK Law, HL Moses
Journal of Biological Chemistry 274 (52), 37413-37420, 1999
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production
ME Waltner-Law, XL Wang, BK Law, RK Hall, M Nawano, DK Granner
Journal of Biological Chemistry 277 (38), 34933-34940, 2002
Activation of the Erk pathway is required for TGF-β1-induced EMT in vitro
L Xie, BK Law, AM Chytil, KA Brown, ME Aakre, HL Moses
Neoplasia 6 (5), 603-610, 2004
Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition
T Lin, A Ponn, X Hu, BK Law, J Lu
Oncogene 29 (35), 4896-4904, 2010
Rapamycin: an anti-cancer immunosuppressant?
BK Law
Critical reviews in oncology/hematology 56 (1), 47-60, 2005
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line
L Xie, BK Law, ME Aakre, M Edgerton, Y Shyr, NA Bhowmick, HL Moses
Breast Cancer Research 5 (6), 1-12, 2003
ErbB2/Neu-Induced, Cyclin D1-Dependent Transformation Is Accelerated in p27-Haploinsufficient Mammary Epithelial Cells but Impaired in p27-Null Cells
RS Muraoka, AEG Lenferink, B Law, E Hamilton, DM Brantley, ...
Molecular and cellular biology 22 (7), 2204-2219, 2002
TGF-β signaling is essential for joint morphogenesis
A Spagnoli, L O'Rear, RL Chandler, F Granero-Molto, DP Mortlock, ...
The Journal of cell biology 177 (6), 1105-1117, 2007
A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors
D Akin, SK Wang, P Habibzadegah-Tari, B Law, D Ostrov, M Li, XM Yin, ...
Autophagy 10 (11), 2021-2035, 2014
Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation
Y Liu, BK Law, H Luesch
Molecular pharmacology 76 (1), 91-104, 2009
Rapamycin potentiates transforming growth factor β-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
BK Law, A Chytil, N Dumont, EG Hamilton, ME Waltner-Law, ME Aakre, ...
Molecular and cellular biology 22 (23), 8184-8198, 2002
Inactivation of TGF-β signaling in hepatocytes results in an increased proliferative response after partial hepatectomy
J Romero-Gallo, EG Sozmen, A Chytil, WE Russell, R Whitehead, ...
Oncogene 24 (18), 3028-3041, 2005
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor
Y Liu, LA Salvador, S Byeon, Y Ying, JC Kwan, BK Law, J Hong, ...
Journal of Pharmacology and Experimental Therapeutics 335 (2), 351-361, 2010
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen
BK Law, ME Waltner-Law, AJ Entingh, A Chytil, ME Aakre, P Nørgaard, ...
Journal of Biological Chemistry 275 (49), 38261-38267, 2000
The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide
B Law, S Rossie
Journal of Biological Chemistry 270 (21), 12808-12813, 1995
Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway
JL McConnell, RJ Gomez, LRA McCorvey, BK Law, BE Wadzinski
Oncogene 26 (41), 6021-6030, 2007
Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) α and TGFα/neu transgenic mice by inhibition of …
P Nørgaard, B Law, H Joseph, DL Page, Y Shyr, D Mays, JA Pietenpol, ...
Clinical cancer research 5 (1), 35-42, 1999
Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2AC, PP4C, and PP6C) and analysis of the interaction of PP2AC with …
S Kloeker, R Reed, JL McConnell, D Chang, K Tran, RS Westphal, ...
Protein expression and purification 31 (1), 19-33, 2003
Cyclin-dependent kinase inhibitors as anticancer therapeutics
ME Law, PE Corsino, S Narayan, BK Law
Molecular pharmacology 88 (5), 846-852, 2015
Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents
H Yang, CE Pinello, J Luo, D Li, Y Wang, LY Zhao, SC Jahn, ...
Molecular cancer therapeutics 12 (5), 610-620, 2013
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