Intracellular delivery of nanomaterials: how to catch endosomal escape in the act TF Martens, K Remaut, J Demeester, SC De Smedt, K Braeckmans Nano Today 9 (3), 344-364, 2014 | 209 | 2014 |
Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides K Remaut, B Lucas, K Braeckmans, J Demeester, SC De Smedt Journal of controlled release 117 (2), 256-266, 2007 | 135 | 2007 |
Nucleic acid delivery: Where material sciences and bio-sciences meet K Remaut, NN Sanders, BG De Geest, K Braeckmans, J Demeester, ... Materials Science and Engineering: R: Reports 58 (3-5), 117-161, 2007 | 114 | 2007 |
Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes K Remaut, NN Sanders, F Fayazpour, J Demeester, SC De Smedt Journal of controlled release 115 (3), 335-343, 2006 | 108 | 2006 |
Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples K Braeckmans, K Remaut, RE Vandenbroucke, B Lucas, SC De Smedt, ... Biophysical journal 92 (6), 2172-2183, 2007 | 91 | 2007 |
Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines D Vercauteren, H Deschout, K Remaut, JFJ Engbersen, AT Jones, ... ACS nano 5 (10), 7874-7884, 2011 | 84 | 2011 |
Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy TF Martens, K Remaut, H Deschout, JFJ Engbersen, WE Hennink, ... Journal of controlled release 202, 83-92, 2015 | 83 | 2015 |
PEGylation of biodegradable dextran nanogels for siRNA delivery B Naeye, K Raemdonck, K Remaut, B Sproat, J Demeester, SC De Smedt European journal of pharmaceutical sciences 40 (4), 342-351, 2010 | 81 | 2010 |
In situ analysis of single-stranded and duplex siRNA integrity in living cells K Raemdonck, K Remaut, B Lucas, NN Sanders, J Demeester, ... Biochemistry 45 (35), 10614-10623, 2006 | 76 | 2006 |
The proton sponge hypothesis: Fable or fact? LMP Vermeulen, SC De Smedt, K Remaut, K Braeckmans European Journal of Pharmaceutics and Biopharmaceutics 129, 184-190, 2018 | 75 | 2018 |
Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles LMP Vermeulen, T Brans, SK Samal, P Dubruel, J Demeester, ... ACS nano 12 (3), 2332-2345, 2018 | 69 | 2018 |
Mechanistic profiling of the siRNA delivery dynamics of lipid–polymer hybrid nanoparticles S Colombo, D Cun, K Remaut, M Bunker, J Zhang, B Martin-Bertelsen, ... Journal of controlled release 201, 22-31, 2015 | 63 | 2015 |
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine K Remaut, B Lucas, K Raemdonck, K Braeckmans, J Demeester, ... Biomacromolecules 8 (4), 1333-1340, 2007 | 61 | 2007 |
Evading innate immunity in nonviral mRNA delivery: don’t shoot the messenger J Devoldere, H Dewitte, SC De Smedt, K Remaut Drug discovery today 21 (1), 11-25, 2016 | 60 | 2016 |
Measuring the intravitreal mobility of nanomedicines with single-particle tracking microscopy TF Martens, D Vercauteren, K Forier, H Deschout, K Remaut, R Paesen, ... Nanomedicine 8 (12), 1955-1968, 2013 | 57 | 2013 |
Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis—Mission possible? GR Dakwar, M Shariati, W Willaert, W Ceelen, SC De Smedt, K Remaut Advanced drug delivery reviews 108, 13-24, 2017 | 56 | 2017 |
Colloidal stability of nano-sized particles in the peritoneal fluid: Towards optimizing drug delivery systems for intraperitoneal therapy GR Dakwar, E Zagato, J Delanghe, S Hobel, A Aigner, H Denys, ... Acta Biomaterialia 10 (7), 2965-2975, 2014 | 55 | 2014 |
FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery K Remaut, B Lucas, K Braeckmans, NN Sanders, SC De Smedt, ... Journal of controlled release 103 (1), 259-271, 2005 | 54 | 2005 |
Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles K Braeckmans, K Buyens, B Naeye, D Vercauteren, H Deschout, ... Journal of Controlled Release 148 (1), 69-74, 2010 | 53 | 2010 |
Studying biophysical barriers to DNA delivery by advanced light microscopy SC De Smedt, K Remaut, B Lucas, K Braeckmans, NN Sanders, ... Advanced drug delivery reviews 57 (1), 191-210, 2005 | 53 | 2005 |