| The Rap1-RIAM-talin axis of integrin activation and blood cell function F Lagarrigue, C Kim, MH Ginsberg Blood, The Journal of the American Society of Hematology 128 (4), 479-487, 2016 | 139 | 2016 |
| Shigella flexneri Infection Generates the Lipid PI5P to Alter Endocytosis and Prevent Termination of EGFR Signaling D Ramel, F Lagarrigue, V Pons, J Mounier, S Dupuis-Coronas, ... Science signaling 4 (191), ra61-ra61, 2011 | 115 | 2011 |
| A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration F Lagarrigue, P Vikas Anekal, HS Lee, AI Bachir, JN Ablack, AF Horwitz, ... Nature communications 6 (1), 8492, 2015 | 103 | 2015 |
| Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations MA Lopez-Ramirez, G Fonseca, HA Zeineddine, R Girard, T Moore, ... Journal of Experimental Medicine 214 (11), 3331-3346, 2017 | 94 | 2017 |
| Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1 J Viaud, F Lagarrigue, D Ramel, S Allart, G Chicanne, L Ceccato, ... Nature communications 5 (1), 4080, 2014 | 75 | 2014 |
| Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice MA Lopez-Ramirez, A Pham, R Girard, T Wyseure, P Hale, A Yamashita, ... Blood, The Journal of the American Society of Hematology 133 (3), 193-204, 2019 | 67 | 2019 |
| Matrix metalloproteinase-9 is upregulated in nucleophosmin-anaplastic lymphoma kinase–positive anaplastic lymphomas and activated at the cell surface by the chaperone heat … F Lagarrigue, S Dupuis-Coronas, D Ramel, G Delsol, H Tronchère, ... Cancer research 70 (17), 6978-6987, 2010 | 63 | 2010 |
| Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem AR Gingras, F Lagarrigue, MN Cuevas, AJ Valadez, M Zorovich, ... Journal of Cell Biology 218 (6), 1799-1809, 2019 | 59 | 2019 |
| Talin-1 is the principal platelet Rap1 effector of integrin activation F Lagarrigue, DS Paul, AR Gingras, AJ Valadez, H Sun, J Lin, MN Cuevas, ... Blood, The Journal of the American Society of Hematology 136 (10), 1180-1190, 2020 | 56 | 2020 |
| Elevated levels of PtdIns5P in NPM-ALK transformed cells: implication of PIKfyve S Coronas, F Lagarrigue, D Ramel, G Chicanne, G Delsol, B Payrastre, ... Biochemical and biophysical research communications 372 (2), 351-355, 2008 | 47 | 2008 |
| ALK+ALCLs induce cutaneous, HMGB-1–dependent IL-8/CXCL8 production by keratinocytes through NF-κB activation E Dejean, M Foisseau, F Lagarrigue, L Lamant, N Prade, A Marfak, ... Blood, The Journal of the American Society of Hematology 119 (20), 4698-4707, 2012 | 43 | 2012 |
| PtdIns5P protects Akt from dephosphorylation through PP2A inhibition D Ramel, F Lagarrigue, S Dupuis-Coronas, G Chicanne, N Leslie, ... Biochemical and biophysical research communications 387 (1), 127-131, 2009 | 42 | 2009 |
| Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation MA Lopez-Ramirez, CC Lai, SI Soliman, P Hale, A Pham, EJ Estrada, ... The Journal of clinical investigation 131 (13), 2021 | 37 | 2021 |
| Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation F Lagarrigue, AR Gingras, DS Paul, AJ Valadez, MN Cuevas, H Sun, ... Blood advances 2 (18), 2358-2368, 2018 | 34 | 2018 |
| Distinct integrin activation pathways for effector and regulatory T cell trafficking and function H Sun, F Lagarrigue, H Wang, Z Fan, MA Lopez-Ramirez, JT Chang, ... Journal of Experimental Medicine 218 (2), 2021 | 32 | 2021 |
| The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness S Dupuis-Coronas, F Lagarrigue, D Ramel, G Chicanne, E Saland, ... Journal of Biological Chemistry 286 (37), 32105-32114, 2011 | 27 | 2011 |
| Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development H Sun, F Lagarrigue, AR Gingras, Z Fan, K Ley, MH Ginsberg Journal of Cell Biology 217 (4), 1453-1465, 2018 | 25 | 2018 |
| SnapShot: talin and the modular nature of the integrin adhesome F Ye, F Lagarrigue, MH Ginsberg Cell 156 (6), 1340-1340. e1, 2014 | 24 | 2014 |
| Cutting Edge: Loss of T cell RIAM precludes conjugate formation with APC and prevents immune-mediated diabetes F Lagarrigue, FB Gertler, MH Ginsberg, JM Cantor The Journal of Immunology 198 (9), 3410-3415, 2017 | 15 | 2017 |
| The Connection Between Rap1 and Talin1 in the Activation of Integrins in Blood Cells H Sun, F Lagarrigue, MH Ginsberg Frontiers in Cell and Developmental Biology 10, 908622, 2022 | 7 | 2022 |
Mark H GinsbergUniversity of California San DiegoGeverifieerd e-mailadres voor ucsd.edu
