Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome RW Tothill, AV Tinker, J George, R Brown, SB Fox, S Lade, DS Johnson, ... Clinical cancer research 14 (16), 5198-5208, 2008 | 1217 | 2008 |
Whole–genome characterization of chemoresistant ovarian cancer AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ... Nature 521 (7553), 489-494, 2015 | 946 | 2015 |
Next-generation sequencing for cancer diagnostics: a practical perspective C Meldrum, MA Doyle, RW Tothill The Clinical Biochemist Reviews 32 (4), 177, 2011 | 466 | 2011 |
Options available—from start to finish—for obtaining data from DNA microarrays II AJ Holloway, RK Van Laar, RW Tothill, DDL Bowtell Nature genetics 32 (4), 481-489, 2002 | 371 | 2002 |
CONTRA: copy number analysis for targeted resequencing J Li, R Lupat, KC Amarasinghe, ER Thompson, MA Doyle, GL Ryland, ... Bioinformatics 28 (10), 1307-1313, 2012 | 276 | 2012 |
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas D Etemadmoghadam, A Defazio, R Beroukhim, C Mermel, J George, ... Clinical cancer research 15 (4), 1417-1427, 2009 | 248 | 2009 |
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ... The Lancet Oncology 17 (10), 1386-1395, 2016 | 232 | 2016 |
An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin RW Tothill, A Kowalczyk, D Rischin, A Bousioutas, I Haviv, RK Van Laar, ... Cancer research 65 (10), 4031-4040, 2005 | 231 | 2005 |
Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles ER Thompson, MA Doyle, GL Ryland, SM Rowley, DYH Choong, ... PLoS Genet 8 (9), e1002894, 2012 | 200 | 2012 |
UV-associated mutations underlie the etiology of MCV-negative Merkel cell carcinomas SQ Wong, K Waldeck, IA Vergara, J Schröder, J Madore, JS Wilmott, ... Cancer research 75 (24), 5228-5234, 2015 | 189 | 2015 |
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells L Pirola, A Balcerczyk, RW Tothill, I Haviv, A Kaspi, S Lunke, M Ziemann, ... Genome research 21 (10), 1601-1615, 2011 | 185 | 2011 |
BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage VJ Mar, SQ Wong, J Li, RA Scolyer, C McLean, AT Papenfuss, RW Tothill, ... Clinical Cancer Research 19 (17), 4589-4598, 2013 | 118 | 2013 |
Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors MS Anglesio, JM Arnold, J George, AV Tinker, R Tothill, N Waddell, ... Molecular cancer research 6 (11), 1678-1690, 2008 | 117 | 2008 |
An evolutionarily conserved function of polycomb silences the MHC Class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer Cell 36 (4), 385-401. e8, 2019 | 99 | 2019 |
68 Ga-DOTATATE and 18 F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity CA Chang, DA Pattison, RW Tothill, G Kong, TJ Akhurst, RJ Hicks, ... Cancer Imaging 16 (1), 1-12, 2016 | 92 | 2016 |
Massively‐parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary RW Tothill, J Li, L Mileshkin, K Doig, T Siganakis, P Cowin, A Fellowes, ... The Journal of pathology 231 (4), 413-423, 2013 | 85 | 2013 |
Loss of heterozygosity: what is it good for? GL Ryland, MA Doyle, D Goode, SE Boyle, DYH Choong, SM Rowley, J Li, ... BMC medical genomics 8 (1), 1-12, 2015 | 75 | 2015 |
Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads J Schröder, A Hsu, SE Boyle, G Macintyre, M Cmero, RW Tothill, ... Bioinformatics 30 (8), 1064-1072, 2014 | 75 | 2014 |
The genomic landscape of phaeochromocytoma A Flynn, D Benn, R Clifton‐Bligh, B Robinson, AH Trainer, P James, ... The Journal of pathology 236 (1), 78-89, 2015 | 61 | 2015 |
A signature predicting poor prognosis in gastric and ovarian cancer represents a coordinated macrophage and stromal response RA Busuttil, J George, RW Tothill, K Ioculano, A Kowalczyk, C Mitchell, ... Clinical cancer research 20 (10), 2761-2772, 2014 | 58 | 2014 |