Nanobodies as therapeutics: big opportunities for small antibodies S Steeland, RE Vandenbroucke, C Libert Drug discovery today 21 (7), 1076-1113, 2016 | 404 | 2016 |
A new venue of TNF targeting S Steeland, C Libert, RE Vandenbroucke International journal of molecular sciences 19 (5), 1442, 2018 | 140 | 2018 |
Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease S Steeland, N Gorlé, C Vandendriessche, S Balusu, M Brkic, ... EMBO molecular medicine 10 (4), e8300, 2018 | 90 | 2018 |
Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1 S Steeland, L Puimège, RE Vandenbroucke, F Van Hauwermeiren, ... Journal of Biological Chemistry 290 (7), 4022-4037, 2015 | 76 | 2015 |
TNFR1 inhibition with a Nanobody protects against EAE development in mice S Steeland, S Van Ryckeghem, G Van Imschoot, R De Rycke, ... Scientific Reports 7 (1), 13646, 2017 | 49 | 2017 |
Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR 1 L Puimège, F Van Hauwermeiren, S Steeland, S Van Ryckeghem, ... EMBO molecular medicine 7 (8), 1004-1017, 2015 | 46 | 2015 |
Topical imiquimod yields systemic effects due to unintended oral uptake L Grine, S Steeland, S Van Ryckeghem, M Ballegeer, S Lienenklaus, ... Scientific reports 6 (1), 20134, 2016 | 41 | 2016 |
Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8 D Demeestere, E Dejonckheere, S Steeland, P Hulpiau, J Haustraete, ... Molecular Therapy 24 (5), 890-902, 2016 | 25 | 2016 |
Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis S Steeland, S Van Ryckeghem, J Vandewalle, M Ballegeer, ... Critical care medicine 46 (1), e67-e75, 2018 | 15 | 2018 |
A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice J Vandewalle, S Steeland, S Van Ryckeghem, M Eggermont, ... Frontiers in Immunology 10, 2574, 2019 | 14 | 2019 |
Efficient analysis of mouse genome sequences reveal many nonsense variants S Steeland, S Timmermans, S Van Ryckeghem, P Hulpiau, Y Saeys, ... Proceedings of the National Academy of Sciences 113 (20), 5670-5675, 2016 | 6 | 2016 |
Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer’s disease puzzle S Steeland, RE Vandenbroucke Neural Regeneration Research 14 (7), 1144-1147, 2019 | 5 | 2019 |
脉络丛中的肿瘤坏死因子受体 1: 复杂阿尔茨海默病困局中的神经炎症因子 S Steeland, RE Vandenbroucke 中国神经再生研究 (英文版) 14 (7), 1144, 2019 | | 2019 |
Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases S Steeland Ghent University, 2017 | | 2017 |
Online Data Supplement Methods and materials S Steeland, S Van Ryckeghem, J Vandewalle, M Ballegeer, ... | | |