| The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus I Lauritzen, R Pardossi-Piquard, C Bauer, E Brigham, JD Abraham, ... Journal of Neuroscience 32 (46), 16243-16255, 2012 | 203 | 2012 |
| The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus I Lauritzen, R Pardossi-Piquard, C Bauer, E Brigham, JD Abraham, ... Journal of Neuroscience 32 (46), 16243-16255, 2012 | 203 | 2012 |
| Are N-and C-terminally truncated Aβ species key pathological triggers in Alzheimer's disease? J Dunys, A Valverde, F Checler Journal of Biological Chemistry 293 (40), 15419-15428, 2018 | 101 | 2018 |
| Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation T Goiran, E Duplan, L Rouland, W El Manaa, I Lauritzen, J Dunys, H You, ... Cell Death & Differentiation, 1-12, 2018 | 96 | 2018 |
| The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model M Cissé, E Duplan, T Lorivel, J Dunys, C Bauer, X Meckler, Y Gerakis, ... Molecular psychiatry 22 (11), 1562-1575, 2017 | 96 | 2017 |
| 6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes α-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation. CA da Costa, J Dunys, F Brau, S Wilk, R Cappai, F Checler The Journal of Biological Chemistry 288 (29), 21208, 2013 | 65* | 2013 |
| Induced pluripotent stem cell-derived vascular smooth muscle cells: methods and application BC Dash, Z Jiang, C Suh, Y Qyang Biochemical Journal 465 (2), 185-194, 2015 | 60 | 2015 |
| Neprilysin activity and expression are controlled by nicastrin R Pardossi‐Piquard, J Dunys, G Yu, P St. George‐Hyslop, ... Journal of neurochemistry 97 (4), 1052-1056, 2006 | 59 | 2006 |
| β-Amyloid precursor protein intracellular domain controls mitochondrial function by modulating phosphatase and tensin homolog–induced kinase 1 transcription in cells and in … T Goiran, E Duplan, M Chami, A Bourgeois, W El Manaa, L Rouland, ... Biological psychiatry 83 (5), 416-427, 2018 | 52 | 2018 |
| Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB … G Barthet, J Dunys, Z Shao, Z Xuan, Y Ren, J Xu, N Arbez, G Mauger, ... Neurobiology of aging 34 (2), 499-510, 2013 | 52 | 2013 |
| γ-Secretase-mediated regulation of neprilysin: influence of cell density and aging and modulation by imatinib C Bauer, R Pardossi-Piquard, J Dunys, M Roy, F Checler Journal of Alzheimer's Disease 27 (3), 511-520, 2011 | 48 | 2011 |
| p53 is regulated by and regulates members of the γ-secretase complex F Checler, J Dunys, R Pardossi-Piquard, C Alves da Costa Neurodegenerative Diseases 7 (1-3), 50-55, 2010 | 41 | 2010 |
| The transcription factor X-box binding protein-1 in neurodegenerative diseases J Dunys, E Duplan, F Checler Molecular neurodegeneration 9, 1-8, 2014 | 34 | 2014 |
| p53-dependent Aph-1 and Pen-2 anti-apoptotic phenotype requires the integrity of the γ-secretase complex but is independent of its activity J Dunys, T Kawarai, J Sevalle, V Dolcini, PS George-Hyslop, ... Journal of biological chemistry 282 (14), 10516-10525, 2007 | 34 | 2007 |
| p53‐Dependent control of cell death by nicastrin: lack of requirement for presenilin‐dependent γ‐secretase complex R Pardossi‐Piquard, J Dunys, E Giaime, MV Guillot‐Sestier, ... Journal of neurochemistry 109 (1), 225-237, 2009 | 28 | 2009 |
| Response to correspondence: Pardossi-Piquard et al.,“Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and … R Pardossi-Piquard, J Dunys, T Kawarai, C Sunyach, CA da Costa, ... Neuron 53 (4), 483-486, 2007 | 28 | 2007 |
| Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1 Y Gerakis, J Dunys, C Bauer, F Checler Scientific Reports 6 (1), 37436, 2016 | 25 | 2016 |
| Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins J Dunys, T Kawarai, S Wilk, P St. George-Hyslop, C Alves Da Costa, ... Biochemical Journal 394 (2), 501-509, 2006 | 23 | 2006 |
| p53-dependent control of transactivation of the Pen2 promoter by presenilins J Dunys, J Sevalle, E Giaime, R Pardossi-Piquard, MP Vitek, P Renbaum, ... Journal of cell science 122 (21), 4003-4008, 2009 | 22 | 2009 |
| TMP21 regulates Aβ production but does not affect caspase-3, p53, and neprilysin V Dolcini, J Dunys, J Sevalle, F Chen, MV Guillot-Sestier, ... Biochemical and biophysical research communications 371 (1), 69-74, 2008 | 21 | 2008 |
