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Ty D. Troutman
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IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
KM Lin, W Hu, TD Troutman, M Jennings, T Brewer, X Li, S Nanda, ...
Proceedings of the National Academy of Sciences 111 (2), 775-780, 2014
3132014
Niche-specific reprogramming of epigenetic landscapes drives myeloid cell diversity in nonalcoholic steatohepatitis
JS Seidman, TD Troutman, M Sakai, A Gola, NJ Spann, H Bennett, ...
Immunity 52 (6), 1057-1074. e7, 2020
2832020
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity
M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ...
Immunity 51 (4), 655-670. e8, 2019
2632019
Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K
TD Troutman, JF Bazan, C Pasare
Cell cycle 11 (19), 3559-3567, 2012
2382012
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
TD Troutman, W Hu, S Fulenchek, T Yamazaki, T Kurosaki, JF Bazan, ...
Proceedings of the National Academy of Sciences 109 (1), 273-278, 2012
2072012
Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function
VM Link, SH Duttke, HB Chun, IR Holtman, E Westin, MA Hoeksema, ...
Cell 173 (7), 1796-1809. e17, 2018
1592018
TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation
RA Irizarry-Caro, MM McDaniel, GR Overcast, VG Jain, TD Troutman, ...
Proceedings of the National Academy of Sciences 117 (48), 30628-30638, 2020
1482020
Neutralization of oxidized phospholipids ameliorates non-alcoholic steatohepatitis
X Sun, JS Seidman, P Zhao, TD Troutman, NJ Spann, X Que, F Zhou, ...
Cell metabolism 31 (1), 189-206. e8, 2020
1382020
Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment
W Hu, TD Troutman, R Edukulla, C Pasare
Immunity 35 (6), 1010-1022, 2011
1342011
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages
ED Muse, S Yu, CR Edillor, J Tao, NJ Spann, TD Troutman, JS Seidman, ...
Proceedings of the National Academy of Sciences 115 (20), E4680-E4689, 2018
982018
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells
KA Allison, E Sajti, JG Collier, D Gosselin, TD Troutman, EL Stone, ...
Elife 5, e10134, 2016
802016
Heterogeneity of HSC s in a Mouse Model of NASH
SB Rosenthal, X Liu, S Ganguly, D Dhar, MP Pasillas, E Ricciardelli, RZ Li, ...
Hepatology 74 (2), 667-685, 2021
792021
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages
DZ Eichenfield, TD Troutman, VM Link, MT Lam, H Cho, D Gosselin, ...
elife 5, e13024, 2016
712016
BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation
K Deason, TD Troutman, A Jain, DK Challa, R Mandraju, T Brewer, ...
Journal of Experimental Medicine 215 (9), 2413-2428, 2018
542018
Epigenetic regulation of kupffer cell function in health and disease
H Bennett, TD Troutman, M Sakai, CK Glass
Frontiers in Immunology 11, 609618, 2021
442021
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice
SM Moore, JS Seidman, J Ellegood, R Gao, A Savchenko, TD Troutman, ...
Translational psychiatry 9 (1), 24, 2019
372019
Exploiting dynamic enhancer landscapes to decode macrophage and microglia phenotypes in health and disease
TD Troutman, E Kofman, CK Glass
Molecular cell 81 (19), 3888-3903, 2021
352021
Mannose-containing oligosaccharides of non-specific human secretory immunoglobulin A mediate inhibition of Vibrio cholerae biofilm formation
AK Murthy, BKR Chaganty, T Troutman, MN Guentzel, JJ Yu, SK Ali, ...
PLoS One 6 (2), e16847, 2011
352011
Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis
K Arimoto, S Miyauchi, TD Troutman, Y Zhang, M Liu, SA Stoner, ...
Nature Communications 14 (1), 251, 2023
182023
Breaking down the complex pathophysiology of eosinophilic esophagitis
B Underwood, TD Troutman, JT Schwartz
Annals of Allergy, Asthma & Immunology 130 (1), 28-39, 2023
172023
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Artikelen 1–20